50 completed, 8 not yet recruiting, 8 unknown, 5 recruiting. 74 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 74 | Completed 50, Not yet recruiting 8, Unknown 8, Recruiting 5, Active not recruiting 3 |
| Phase 2 | 7 | Completed 3, Recruiting 3, Not yet recruiting 1 |
Follow Gingival Diseases: new trials by email Literature Review of Gingival Diseases trials Research Report on Gingival Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences Toothpaste Tablet, Conventional Toothpaste - Gingival Inflammation, Dental Caries | Phase 3 | Not yet recruiting | Loma Linda University | 50 | 2026-12-01 | 2026-07-10 |
| Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis 0.412% stannous fluoride toothpaste and flat trimmed toothbrush, 0.76% Na MFP and flat trimmed toothbrush - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 84 | 2026-10-09 | 2026-11-10 |
| Clinical Study Examining the Control of Plaque and Gingivitis Silica Free Meridol, Meridol, Colgate Dental Product - Gingivitis | Phase 3 | Not yet recruiting | Colgate Palmolive | 135 | 2026-10-01 | 2026-09-25 |
| Surgical Treatment for Gingival Recessions After Orthodontic Treatment Coronally advanced flap and a de-epithelialized soft tissue graft, Coronally advanced flap and a subepithelial connective tissue graft, Coronally advanced flap and Mucoderm soft tissue collagen graft - Gingival Recessions, Generalized | Phase 2 / Phase 3 | Recruiting | Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors | 75 | 2026-09-01 | 2026-08-13 |
| Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal Treatment Active Oral Hygiene Regimen, Placebo Oral Hygiene Regimen - Periodontal Disease, Gingival Inflammation and Bleeding | Phase 3 | Not yet recruiting | Colgate Palmolive | 100 | 2026-09-01 | 2026-09-03 |
| New In Situ Model Design for Caries and Erosion 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste - Caries, Erosive Tooth Wear | Phase 3 | Active not recruiting | Indiana University | 12 | 2026-08-03 | 2026-09-30 |
| Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste - Plaque, Dental Plaque | Phase 3 | Recruiting | Colgate Palmolive | 120 | 2026-07-20 | 2026-09-25 |
| Topical Phenytoin for Management of Gingival Recession phenytoin cream, Placebo - Gingival Recession | Phase 2 / Phase 3 | Not yet recruiting | Cairo University | 30 | 2026-06-01 | 2026-05-15 |
| Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2026-05-18 | 2026-09-24 |
| To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis. Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB - Plaque, Dental, Gingivitis | Phase 3 | Active not recruiting | Colgate Palmolive | 85 | 2026-05-11 | 2026-05-27 |
| Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding Toothpaste containing chitosan, Colgate Cavity Protection Toothpaste - Plaque, Dental, Gingivitis | Phase 3 | Not yet recruiting | Colgate Palmolive | 90 | 2026-04-01 | 2026-04-13 |
| Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial Xylitol Chewing gum, Sorbitol chewing gum - Preterm Birth, Low Birthweight Neonate | Phase 2 / Phase 3 | Recruiting | University of Washington | 6000 | 2026-03-26 | 2026-09-10 |
| Homemade Herbal Mouthwash in Gingivitis. A Randomized Clinical Trial. Chlorhexidine 0,12%, herbal Mouthwash - Gingivitis | Phase 3 | Not yet recruiting | Cairo University | 12 | 2026-02-01 | 2026-02-10 |
| Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis. 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque | Phase 3 | Completed | Colgate Palmolive | 134 | 2026-01-26 | 2026-05-22 |
| Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes CHX mouthwash, Oxygen-enriched mouthwash - Periodontal Disease, Periodontal Diseases Inflammation | Phase 3 | Completed | Cairo University | 72 | 2025-12-01 | 2026-10-06 |
| Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control Mouthwash cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash, sodium fluoride Mouthwash - Gingivitis, Plaque, Dental | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-12-01 | 2026-05-26 |
| The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 130 | 2025-10-14 | 2026-10-29 |
| Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children 0.12% Chlorhexidine Mouthwash ( Hexitol ), Triphila mouthwash - Plaque Accumulation, Gingival Inflammation | Phase 3 | Not yet recruiting | Cairo University | 36 | 2025-09-01 | 2025-06-12 |
| Clinical Investigation of PerioGard (Test) Regimen PeriGuard regimen, Colgate Dental Cream regimen - Gingivitis | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-08-18 | 2026-03-18 |
Showing 20 of 74. Sign in to see all of them.
Gingivitis (52) · Dental Plaque (16) · Plaque, Amyloid (16) · Gingival Recession (11) · Periodontal Diseases (8) · Gingival Hemorrhage (7) · Periodontitis (5) · Consumer Behavior (2) · Gingival Hyperplasia (2) · Hemorrhage (2) · Mouth Diseases (2) · Premature Birth (2) · Bronchiolitis Obliterans Syndrome (1) · Chronic Periodontitis (1)
Stomatognathic Diseases (74) · Mouth Diseases (72) · Periodontal Diseases (66) · Infections (52) · Pathological Conditions, Signs and Symptoms (23) · Tooth Diseases (20) · Dental Deposits (17) · Pathological Conditions, Anatomical (16) · Pathologic Processes (11) · Periodontal Atrophy (11) · Oral Hemorrhage (7) · Hemorrhage (6) · Behavior (3) · Signs and Symptoms (3)
Triclosan (8) · Fluorides (7) · hydrated silica gel-based toothpaste (6) · Toothpastes (5) · Cetylpyridinium (4) · fluorophosphate (4) · Chlorhexidine (3) · Supersmile (3) · Dental Devices, Home Care (2) · Hyaluronic Acid (2) · Hydrogen Peroxide (2) · chlorhexidine gluconate (2) · cytidylyl-(3'-5')-cytidine (2) · Betaine (1) · Bicarbonates (1)
Colgate Palmolive (32) · Cairo University (6) · University of Baghdad (4) · Loma Linda University (2) · University of British Columbia (2) · University of Milan (2) · Aga Khan University (1) · Al-Mustansiriyah University (1) · Alexandria University (1) · All India Institute of Medical Sciences (1) · Anahuac Mayab University (1) · Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors (1) · Bulent Ecevit University (1) · Can Tho University of Medicine and Pharmacy (1) · Dow University of Health Sciences (1)
United States (15) · Italy (6) · Brazil (5) · China (5) · Egypt (5) · Iraq (5) · Spain (3) · Thailand (3) · Canada (2) · Croatia (2) · India (2) · Mexico (2) · Pakistan (2) · Puerto Rico (2) · Azerbaijan (1)
Cassiano K Rosing, PhD (2) · Deyu Hu, DDS, MS (2) · Giampietro Farronato, Professor (2) · Gianguido Cossellu, Fellow (2) · Luigi Montesani, DDS (2) · So Ran Kwon, DDS, MS, PhD (2) · Yanfang Ren, DDS (2) · Ana Badovinac, assoc prof (1) · Anderson Hara, DDS, PhD (1) · Antonio Cepeda-Bravo, D.D.S., M.S (1) · Augusto E Boneta, DDS (1) · Augusto R Elias-Boneta, DMD, MSD (1) · Augusto R. Elias-Boneta, DMD.MSD (1) · Daniel Erchick, PhD (1)
PMID 12839405, PMID 21085810, PMID 21482950, PMID 21513473, PMID 21897640, PMID 24698829, PMID 24850703, PMID 25277459, PMID 25478471, PMID 25624634, PMID 26427569, PMID 32216778, PMID 34134691, PMID 35287956, PMID 35968157, PMID 38217757, PMID 38594113, PMID 38745306, PMID 39275820, PMID 41328922, PMID 41981946
R01HD119029 (1), R01HD119055 (1)