11 completed, 8 recruiting, 6 unknown, 1 active not recruiting. 16 Not applicable, 4 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Recruiting 6, Completed 5, Unknown 4, Withdrawn 1 |
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Generalized Anxiety: new trials by email Literature Review of Generalized Anxiety trials Research Report on Generalized Anxiety
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neural Mechanisms of Real-world Emotions and Internalizing Academic Performance Feedback - Major Depression, Generalized Anxiety | Not applicable | Recruiting | University of Miami | 144 | 2026-08-24 | 2026-10-23 |
| Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders Group ultra-brief transdiagnostic cognitive-behavioral therapy, Group brief transdiagnostic cognitive-behavioral therapy, Individual ultra-brief transdiagnostic cognitive-behavioral therapy - Depression - Major Depressive Disorder, Generalized Anxiety Disorder | Not applicable | Recruiting | Universidad de Córdoba | 184 | 2026-04-28 | 2026-10-02 |
| Optimization of Late Imagery Rescripting Research Using Generative Artificial Intelligence Imagery Rescripting Intervention - Generalized Anxiety, Fear of Failure | Not applicable | Recruiting | University of Social Sciences and Humanities, Warsaw | 40 | 2026-04-01 | 2026-05-07 |
| Enhancing Health in Rural Populations: Music as Therapy Music Based Intervention - Stress, Generalized Anxiety | Not applicable | Recruiting | Northern Arizona University | 60 | 2026-03-12 | 2026-04-20 |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence Imagery Rescripting Intervention (AI-Generated) - Generalized Anxiety, Fear of Failure | Not applicable | Recruiting | University of Social Sciences and Humanities, Warsaw | 80 | 2025-06-01 | 2025-09-24 |
| P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety Centanafadine, Placebo - ADHD, Anxiety | Phase 3 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 315 | 2025-03-26 | 2026-05-06 |
| Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study. New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale) - Generalized Anxiety, Introspective & Anxiety-Prone Patient | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 545 | 2025-03-18 | 2026-07-31 | |
| Common Factors Group Psychotherapy for General Mental Health Concerns Common Factors Group Psychotherapy - Major Depression, Generalized Anxiety | Not applicable | Withdrawn | University of Alabama at Birmingham | 2025-01-17 | 2026-06-18 | |
| Cerina-A Pilot Randomized Controlled Trial Treatment - Treatment Adherence, Generalized Anxiety | Not applicable | Unknown | Cerina Therapeutics | 90 | 2023-04-24 | 2023-12-20 |
| Imagery Rescripting and Imaginal Exposure for Anxiety Symptoms Imaginal exposure for memories, Imaginal exposure for future events, Imagery rescripting for memories - Social Anxiety, Generalized Anxiety | Not applicable | Unknown | Hebrew University of Jerusalem | 460 | 2022-04-14 | 2022-10-26 |
| Scaling Mental Healthcare in COVID-19 With Voice Biomarkers Major Depressive Disorder, Generalized Anxiety | Completed | Kintsugi Mindful Wellness, Inc. | 20 | 2022-01-12 | 2022-09-30 | |
| Experiences of Anger in Patients in Primary Health Care With Symptoms of Generalized Anxiety No intervention - Generalized Anxiety, Anger | Recruiting | Kronoberg County Council | 40 | 2020-10-19 | 2025-04-16 | |
| Brain Stimulation & Generalized Anxiety Study Cranial Electrotherapy Stimulator (CES) Device - Anxiety, Generalized Anxiety Disorder | Phase 4 | Active not recruiting | ProofPilot | 150 | 2020-10-15 | 2021-02-12 |
| The Impact of Information Sources on Mental Health During the COVID-19 Pandemic Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health - Depression, Generalized Anxiety | Unknown | University of Oslo | 4000 | 2020-06-22 | 2020-06-23 | |
| Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety Online Cognitive Behavioural Therapy - Prenatal Anxiety, Generalized Anxiety | Not applicable | Unknown | University of Zurich | 300 | 2020-06-01 | 2019-12-03 |
| Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in Oman During COVID-19 Pandemic Therapist Guided E-Therapy, Self-Help Therapy - Depressive Symptoms, Generalized Anxiety | Phase 3 | Unknown | Sultan Qaboos University | 70 | 2020-06-01 | 2020-05-08 |
| Meditation and Kundalini Yoga for Heightened Anxiety Related to COVID-19 Anxiety Reduction Training, Kundalini Yoga and Anxiety Reduction Training, Meditation and Anxiety Reduction Training - Generalized Anxiety, Health Anxiety | Not applicable | Completed | Research Foundation for Mental Hygiene, Inc. | 256 | 2020-05-25 | 2024-09-19 |
| The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's) Cross-sectional study investigating the association of NPIs with mental health - Depression, Generalized Anxiety | Completed | University of Oslo | 10084 | 2020-03-31 | 2020-04-24 | |
| Improving Access to Child Anxiety Treatment Exposure Therapy - Obsessive-Compulsive Disorder, Anxiety Disorders | Not applicable | Unknown | Bradley Hospital | 379 | 2018-07-01 | 2022-08-03 |
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Generalized Anxiety Disorder (27) · Anxiety Disorders (10) · Depression (6) · Depressive Disorder, Major (5) · Panic Disorder (5) · Phobia, Social (5) · Agoraphobia (2) · Anxiety, Separation (2) · Mutism (2) · Obsessive-Compulsive Disorder (2) · Phobic Disorders (2) · Rumination Syndrome (2) · Stress Disorders, Post-Traumatic (2) · Anorexia (1) · Attention Deficit Disorder with Hyperactivity (1)
Mental Disorders (26) · Anxiety Disorders (17) · Behavior (7) · Behavioral Symptoms (6) · Depressive Disorder (5) · Mood Disorders (5) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Neurodevelopmental Disorders (3) · Neurologic Manifestations (3) · Phobic Disorders (3) · Communication Disorders (2) · Digestive System Diseases (2) · Feeding and Eating Disorders (2) · Gastrointestinal Diseases (2)
SR 48968 (2) · Cognitive Behavioral Therapy (1) · Early Detection of Cancer (1) · Escitalopram (1) · Implosive Therapy (1) · Meditation (1) · Mental Health (1) · Prospective Studies (1) · Rehabilitation, Vocational (1) · Therapeutics (1)
Amager Hospital (2) · Bradley Hospital (2) · Sanofi (2) · University of Oslo (2) · University of Social Sciences and Humanities, Warsaw (2) · Centre Hospitalier Universitaire de Saint Etienne (1) · Cerina Therapeutics (1) · Hebrew University of Jerusalem (1) · Kintsugi Mindful Wellness, Inc. (1) · Kronoberg County Council (1) · Northern Arizona University (1) · Nova Scotia Health Authority (1) · Otsuka Pharmaceutical Development & Commercialization, Inc. (1) · ProofPilot (1) · Research Foundation for Mental Hygiene, Inc. (1)
United States (10) · Canada (2) · Denmark (2) · France (2) · Poland (2) · Sweden (2) · Australia (1) · Belgium (1) · Finland (1) · Israel (1) · Italy (1) · Norway (1) · Puerto Rico (1) · Spain (1) · Switzerland (1)
Asle Hoffart, PhD (2) · Sverre Urnes Johnson, PhD (2) · Aaron S Heller, PhD (1) · Brian A Fallon, MD (1) · Drew Whittington, MS, MA (1) · Gerard Leavey, Prof. dr (1) · Janine Olthuis, PhD (1) · Jennifer Freeman, PhD (1) · Jonathan D Huppert, PhD (1) · Kelly C. Berg, PhD (1) · Lene F Eplov, MD PhD (1)
PMID 28814317, PMID 29197414, PMID 33203365, PMID 33512323, PMID 34678750, PMID 34916330, PMID 36849841, PMID 38950994, PMID 41066166, PMID 42678901
R01MH142713 (1), U54MD012388 (1)