57 completed, 16 recruiting, 16 unknown, 6 not yet recruiting. 80 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
Follow Rumination Syndrome: new trials by email Literature Review of Rumination Syndrome trials Research Report on Rumination Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message - Psychosis, Anxiety | Not applicable | Not yet recruiting | Mclean Hospital | 10 | 2027-01-15 | 2026-10-05 |
| Rumination-Tailored Guided Internet-Based CBT-I for University Students Guided Internet-Based Cognitive Behavioral Therapy for Insomnia (iCBT-I), Rumination-Tailored Rule-Based Personalized Feedback - Insomnia, Insomnia Disorder | Not applicable | Active not recruiting | Shahid Beheshti University of Medical Sciences | 70 | 2026-07-04 | 2026-07-14 |
| Psychoeducation Based on Acceptance and Commitment Therapy Acceptance and Commitment Therapy-Based Psychoeducation, control group - Panic Disorder | Not applicable | Completed | Muğla Sıtkı Koçman University | 50 | 2026-06-21 | 2026-10-13 |
| Metacognitive Bibliotherapy for Anxiety, Depression, and Metacognitions in University Students The Art of Letting Go - How to Stop Rumination | Book 1, Anchored | Book 2 - Anxiety, Depression | Not applicable | Not yet recruiting | Istanbul Nisantasi University | 110 | 2026-06-15 | 2026-06-04 |
| Optimization of Late Imagery Rescripting Research Using Generative Artificial Intelligence Imagery Rescripting Intervention - Generalized Anxiety, Fear of Failure | Not applicable | Recruiting | University of Social Sciences and Humanities, Warsaw | 40 | 2026-04-01 | 2026-05-07 |
| The Role of Rumination and Worry in Pain and Functional Limitation in Knee Osteoarthritis Osteo Arthritis Knee, Worries; Pain or Disability | Completed | Fatih Sultan Mehmet Training and Research Hospital | 103 | 2026-03-01 | 2026-09-01 | |
| The Effect of Psychoeducation Program Applied to Older Adults Based on Psychosocial Development Theory on Self-critical Rumination, Self-esteem and Psychological Well-being Psychoeducation Program - Older Adults (65 Years and Older) | Not applicable | Completed | Necmettin Erbakan University | 49 | 2026-02-06 | 2026-09-09 |
| Personalized TACS to Reduce Rumination in Patients with Active Suicidal Ideation Sham alpha-tACS, alpha-tACS - Suicidal Ideation Active, Depression Disorders | Not applicable | Not yet recruiting | Sebastian Olbrich | 50 | 2026-01-01 | 2025-02-18 |
| Readiness and Progress in Emotion Regulation Therapy Emotion Regulation Therapy via Telehealth - Rumination, Worry | Not applicable | Recruiting | Teachers College, Columbia University | 36 | 2025-10-24 | 2026-10-20 |
| The Effect of Cognitive Behavioral Therapy (CBT)-Based Psychoeducation on Cognitive Flexibility and Rumination in the Elderly Cognitive Behavioral Approach-Based Psychoeducation Program - Cognitive Flexibility, Rumination | Not applicable | Not yet recruiting | Ataturk University | 38 | 2025-09-01 | 2025-09-04 |
| Modulation of Cortical Brain Activity During Attentional Control Positive sham neurofeedback, Negative sham neurofeedback, Control - Rumination, Chronic Pain | Recruiting | National Council of Scientific and Technical Research, Argentina | 35 | 2025-07-01 | 2025-09-25 | |
| A Compassionate-focused Intervention for Older People with Bipolar Disorder Compassionate-focused therapy - Bipolar Disorder I or II | Not applicable | Not yet recruiting | University of Manchester | 6 | 2025-07-01 | 2025-03-18 |
| Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence Imagery Rescripting Intervention (AI-Generated) - Generalized Anxiety, Fear of Failure | Not applicable | Recruiting | University of Social Sciences and Humanities, Warsaw | 80 | 2025-06-01 | 2025-09-24 |
| Neurobiological Mechanisms of Pathological Rumination and Effects of Aripiprazole Escitalopram, Aripiprazole 5mg - Major Depressive Disorder (MDD), Rumination | Not applicable | Active not recruiting | Central South University | 108 | 2025-05-08 | 2026-06-12 |
| Treatment of Rumination Biofeedback, Placebo - Rumination Syndrome | Not applicable | Recruiting | Hospital Universitari Vall d'Hebron Research Institute | 40 | 2025-05-02 | 2025-07-09 |
| RCT Protocol for 'OverThinking': A Mobile EMI for Reducing Experiential Avoidance OverThinking - Depression, Anxiety | Not applicable | Not yet recruiting | University of Social Sciences and Humanities, Warsaw | 60 | 2025-05-01 | 2025-05-02 |
| Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants Culturally adapted i-CBT - Depressive Symptoms, Anxiety Symptoms | Not applicable | Recruiting | Karolinska Institutet | 128 | 2025-03-25 | 2025-12-12 |
| Affirmation-Based Podcast Education for Fear of Childbirth and Rumination in Pregnant Women Affirmation-based podcast training - Fear of Childbirth, Rumination | Not applicable | Completed | Istinye University | 120 | 2025-02-14 | 2026-05-15 |
| Effect of Environment on the Central and Peripheral Nervous System Built environment, Natural environment - Rumination | Not applicable | Enrolling by invitation | University of South Florida | 95 | 2025-02-14 | 2025-03-25 |
| Sleep to Reduce Incident Depression Effectively in Peripartum Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU) - Insomnia, Depression | Phase 2 | Recruiting | Henry Ford Health System | 500 | 2024-12-10 | 2026-04-17 |
Showing 20 of 101. Sign in to see all of them.
Depression (36) · Anxiety Disorders (27) · Depressive Disorder, Major (15) · Emotional Regulation (9) · Sleep Initiation and Maintenance Disorders (8) · Generalized Anxiety Disorder (6) · Psychological Well-Being (5) · Stress, Psychological (5) · Fibromyalgia (4) · Bipolar Disorder (3) · Chronic Pain (3) · Depressive Disorder (3) · Feeding and Eating Disorders (3) · Mood Disorders (3)
Digestive System Diseases (101) · Gastrointestinal Diseases (100) · Mental Disorders (100) · Feeding and Eating Disorders (98) · Behavior (48) · Behavioral Symptoms (45) · Mood Disorders (19) · Depressive Disorder (17) · Pathological Conditions, Signs and Symptoms (16) · Nervous System Diseases (15) · Signs and Symptoms (14) · Social Behavior (9) · Dyssomnias (8) · Self-Control (8) · Sleep Disorders, Intrinsic (8)
Biofeedback, Psychology (5) · Mindfulness (4) · Surveys and Questionnaires (3) · Therapeutics (3) · Baclofen (2) · Cognitive Behavioral Therapy (2) · Exercise (2) · Meditation (2) · Amyloid (1) · Aripiprazole (1) · Autogenic Training (1) · Built Environment (1) · Control Groups (1) · Eating (1) · Escitalopram (1)
Massachusetts General Hospital (5) · Henry Ford Health System (4) · Hospital Universitari Vall d'Hebron Research Institute (4) · Centre Hospitalier Universitaire, Amiens (3) · Erasmus Medical Center (3) · Teachers College, Columbia University (3) · University of Social Sciences and Humanities, Warsaw (3) · Claude Bernard University (2) · Columbia University (2) · Istituto Auxologico Italiano (2) · Karolinska Institutet (2) · Lawrence University (2) · Mclean Hospital (2) · Modum Bad (2) · Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (2)
United States (34) · Turkey (Türkiye) (12) · France (8) · United Kingdom (5) · Spain (4) · Belgium (3) · Iran (3) · Netherlands (3) · Germany (2) · Hong Kong (2) · Israel (2) · Italy (2) · Norway (2) · Poland (2) · Romania (2)
Ann-Christine Ehlis, Dr. (2) · Asle Hoffart, PhD (2) · Christopher L Drake, PhD (2) · Douglas S Mennin (2) · Fernando Azpiroz, MD (2) · Lori M Hilt, PhD (2) · Ryan J Jacoby, Ph.D. (2) · Sverre Urnes Johnson, PhD (2) · Allison Nitsch, MD (1) · Amit Bernstein, Ph.D. (1)
PMID 21360283, PMID 24768808, PMID 26075389, PMID 26260007, PMID 27185077, PMID 27880789, PMID 29206813, PMID 31710876, PMID 32559716, PMID 33719795, PMID 33871377, PMID 33892684, PMID 34314285, PMID 34555554, PMID 35054039, PMID 35268378, PMID 35436228, PMID 36055535, PMID 36279218, PMID 36457045, PMID 36617964, PMID 36622879, PMID 36892940, PMID 37137739, PMID 37695740, PMID 37839195, PMID 37848857, PMID 38534105, PMID 38551617, PMID 39137411, PMID 39350528, PMID 39626971, PMID 39970439, PMID 40424024, PMID 41426462, PMID 41702143, PMID 42056628, PMID 42387276
K23MH120351 (1), K99AT004945 (1), R01AG043463 (1), R61MH116080 (1), R61MH132072 (1)