14 completed, 3 recruiting, 1 unknown. 11 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 8, Recruiting 2, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Mutism: new trials by email Literature Review of Mutism trials Research Report on Mutism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| VR Homework Exercises for Selective Mutism Treatment 'Speaking at school, a matter of doing' combined with VR homework exercises - Selective Mutism, Anxiety Disorder of Childhood | Not applicable | Recruiting | Luuk Stapersma | 15 | 2025-08-01 | 2026-10-01 |
| Efficacy of Character Strengths Intervention in Enhancing Character Strengths and Self-esteem Among Adolescents Character Strengths Intervention - Mental Health Issue, Mutism | Not applicable | Completed | Fatima Jinnah Women University | 94 | 2023-09-23 | 2024-02-01 |
| Evaluating an Online Adjunctive Support Following Intensive Services (OASIS) Strategy for Youth With Selective Mutism Remote Caregiver Training, Remote Intensive Group Behavioral Treatment (IGBT) - Selective Mutism | Not applicable | Completed | Florida International University | 11 | 2020-03-06 | 2020-12-16 |
| Improving Access to Child Anxiety Treatment Exposure Therapy - Obsessive-Compulsive Disorder, Anxiety Disorders | Not applicable | Unknown | Bradley Hospital | 379 | 2018-07-01 | 2022-08-03 |
| Factors Influencing Selective Mutism Psychometric questionnaire study - Selective Mutism | Completed | Susanne Walitza | 92 | 2017-08-01 | 2020-01-18 | |
| The Efficacy of Integrated Behavioral Therapy for Selective Mutism Integrated Behavioral Therapy for Selective Mutism - Selective Mutism | Not applicable | Completed | Rabin Medical Center | 60 | 2017-05-14 | 2024-04-16 |
| Evaluating Intensive Group Behavioral Treatment for Children With Selective Mutism Intensive Group Behavioral Treatment (IGBT) - Selective Mutism | Not applicable | Completed | Florida International University | 29 | 2017-02-11 | 2018-08-15 |
| Treatment of Social Anxiety Disorder and Selective Mutism Taming Sneaky Fears, Parent Psycho-education and Child Socialization - Social Anxiety Disorder, Selective Mutism | Not applicable | Completed | The Hospital for Sick Children | 93 | 2015-09-01 | 2019-10-29 |
| Cerebellar Mutism Syndrome Study Infratentorial Neoplasms, Mutism | Recruiting | Copenhagen University Hospital, Rigshospitalet | 2000 | 2014-10-01 | 2026-08-12 | |
| Brief Behavioral Treatment for Anxiety in Young Children Parent-Led Exposure Therapy, Treatment As Usual - Obsessive-compulsive Disorder, Social Phobia | Phase 1 / Phase 2 | Completed | University of South Florida | 58 | 2014-01-01 | 2016-10-06 |
| Evaluating the Results of Physician and Parent Decisions to Treat Selective Mutism With Fluoxetine Fluoxetine - Selective Mutism, Social Anxiety | Phase 2 | Completed | Michigan State University | 6 | 2014-01-01 | 2022-05-18 |
| Posterior Fossa Mutism on Quality of Life Posterior Fossa Mutism | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 24 | 2011-07-01 | 2024-08-28 | |
| Randomised Controlled Treatment Study of Selective Mutism Stimulus fading procedures, Guidance on defocused communication - Selective Mutism | Phase 2 | Completed | Regionsenter for barn og unges psykiske helse | 24 | 2009-06-01 | 2014-06-20 |
| What Treatment Works for Children With Selective Mutism? Interventions at home, in the kindergarten/school - Selective Mutism | Not applicable | Completed | Regionsenter for barn og unges psykiske helse | 7 | 2007-11-01 | 2010-11-25 |
| Integrated Behavioral Therapy for Treating Children With Selective Mutism Integrated behavioral therapy (BT) - Selective Mutism | Not applicable | Completed | University of California, Los Angeles | 21 | 2006-01-01 | 2016-11-28 |
| Web-Based CBT Protocol for Treatment of Selective Mutism Meeky Mouse program, Computer Games - Selective Mutism | Not applicable | Completed | National Healthcare Group, Singapore | 38 | 2005-07-01 | 2014-05-20 |
| Treatment of Childhood Social Phobia Social Effectiveness Therapy for Children (SET-C), Fluoxetine, Pill Placebo - Social Phobia | Phase 3 | Completed | University of Central Florida | 139 | 2001-04-01 | 2013-08-01 |
Anxiety Disorders (6) · Phobia, Social (5) · Anxiety, Separation (3) · Generalized Anxiety Disorder (3) · Obsessive-Compulsive Disorder (3) · Phobic Disorders (3) · Agoraphobia (2) · Panic Disorder (2) · Infratentorial Neoplasms (1) · Musculoskeletal Diseases (1) · Neoplasms (1) · Phobia, Specific (1)
Communication Disorders (18) · Language Disorders (18) · Mental Disorders (18) · Nervous System Diseases (18) · Neurobehavioral Manifestations (18) · Neurodevelopmental Disorders (18) · Neurologic Manifestations (18) · Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (18) · Speech Disorders (18) · Anxiety Disorders (2) · Phobic Disorders (2) · Brain Diseases (1) · Brain Neoplasms (1) · Central Nervous System Diseases (1)
Fluoxetine (2) · Cognitive Behavioral Therapy (1) · Implosive Therapy (1) · Schools (1) · Therapeutics (1)
Bradley Hospital (2) · Florida International University (2) · Regionsenter for barn og unges psykiske helse (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Copenhagen University Hospital, Rigshospitalet (1) · Fatima Jinnah Women University (1) · Luuk Stapersma (1) · Michigan State University (1) · National Healthcare Group, Singapore (1) · Rabin Medical Center (1) · Susanne Walitza (1) · The Hospital for Sick Children (1) · University of California, Los Angeles (1) · University of Central Florida (1) · University of South Florida (1)
United States (9) · Norway (3) · Netherlands (2) · Austria (1) · Belgium (1) · Canada (1) · Czechia (1) · Denmark (1) · Finland (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · Lithuania (1) · Pakistan (1)
Daniel Fung, MBBS, MMed (1) · Hanne Kristensen, MD, PhD (1) · Hanne Kristensen, Ph.D. (1) · Jed Magen, DO (1) · Jennifer Freeman, PhD (1) · Joel Sanchez, MD (1) · John Carlson, PhD (1) · Justin Barterian, MA (1) · Karsten Nysom, MD (1) · Kjeld Schmiegelow, MD, Dr. med (1) · Natalie Hong, M.S. (1) · R. Lindsey Bergman, PhD (1) · Suneeta Monga, MD (1)
PMID 18030084, PMID 20013046, PMID 21391024, PMID 23933108, PMID 25267381, PMID 28637445, PMID 29357099, PMID 32878377, PMID 34390394, PMID 35690008, PMID 40178678, PMID 40643729, PMID 40982141, PMID 41639295
R01MH053703 (1), R34MH070938 (1)