16 completed, 5 unknown, 4 recruiting, 1 suspended. 28 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 28 | Completed 16, Unknown 5, Recruiting 4, Suspended 1, Terminated 1, Withdrawn 1 |
Follow Enterobacteriaceae Infections: new trials by email Literature Review of Enterobacteriaceae Infections trials Research Report on Enterobacteriaceae Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care Pivmecillinam, Standard of Care (Investigator Choice) - Febrile Urinary Tract Infection | Phase 4 | Recruiting | Uppsala University | 560 | 2025-12-01 | 2025-12-17 |
| This Randomized Controlled Trial Evaluates the Comparative Efficacy of Intravenous Meropenem Alone Versus Intravenous Meropenem Combined With Oral Azithromycin in Children Aged 6 Months to Under 5 Years Diagnosed With Blood Culture-confirmed Extensively Drug-resistant Uncomplicated Typhoid Fever Meropenem, Azithromycin + Metronidazole - Extensively Drug-Resistant Typhoid Fever, Typhoid Fever | Phase 4 | Completed | Sheikh Zayed Medical College | 90 | 2025-05-14 | 2026-03-03 |
| Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever Azithromycin, Meropenem Injection - Enteric Fever | Phase 4 | Recruiting | Indus Hospital and Health Network | 40 | 2025-04-22 | 2026-05-08 |
| Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccines Oral typhoid fever vaccine, Oral cholera vaccine - Vaccine-Preventable Diseases, Typhoid Fever | Phase 4 | Completed | Helsinki University Central Hospital | 65 | 2023-10-25 | 2024-12-05 |
| Vellore Typhoid Vaccine Impact Trial Typhoid conjugate Vaccine - Typhoid Fever | Phase 4 | Completed | Christian Medical College, Vellore, India | 72400 | 2023-05-01 | 2026-03-17 |
| PipEracillin/Tazobactam Versus mERoPENem for Treatment of AmpC Producing Blood Stream Infections Piperacillin / Tazobactam Injection, Meropenem - Beta Lactam Resistant Bacterial Infection, Enterobacteriaceae Infections | Phase 4 | Withdrawn | Rambam Health Care Campus | 2022-07-01 | 2025-07-24 | |
| Effectiveness of a Typhoid Conjugate Vaccine in DRC Vi-TT - Typhoid Fever | Phase 4 | Unknown | International Vaccine Institute | 48000 | 2022-02-11 | 2023-04-18 |
| Oral Fosfomycin as Sequential Oral Treatment for Multidrug-Resistant Escherichia Coli in Acute Bacterial Prostatitis Fosfomycin Trometamol Salt, control group - Prostatitis, Escherichia Coli Infection | Phase 4 | Completed | Hospital Mutua de Terrassa | 88 | 2022-01-25 | 2026-10-28 |
| The Immunogenicity and Safety of the Vaccination of Human Papillomavirus Vaccine and Measles-Mumps-Rubella Vaccine HPV+MMR（0d），HPV（6m）, HPV（0d），HPV（6m），MMR（7m）, MMR（0d），HPV（1m），HPV（7m） - Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18 | Phase 4 | Unknown | Zhejiang Provincial Center for Disease Control and Prevention | 300 | 2021-08-25 | 2022-03-29 |
| Evaluation of Typhoid Conjugate Vaccine Effectiveness in Ghana Vi-TT, MCV-A vaccine - Typhoid Fever | Phase 4 | Unknown | International Vaccine Institute | 23000 | 2021-08-24 | 2024-03-08 |
| The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial) Azithromycin, Cefixime, Placebo - Typhoid Fever | Phase 4 | Completed | Oxford University Clinical Research Unit, Vietnam | 2150 | 2021-05-23 | 2026-01-15 |
| Preventing Urinary Tract Infections With E. Coli Nissle: E. coli Nissle, Placebo control - Urinary Tract Infections in Children, Secondary Prevention | Phase 4 | Unknown | University of Oulu | 530 | 2021-01-18 | 2022-07-06 |
| Immunomodulation Therapy for Urinary Tract Infections Uro-Vaxom, Placebo oral tablet - Spinal Cord Injuries, Urinary Tract Infections | Phase 4 | Completed | Swiss Paraplegic Research, Nottwil | 24 | 2020-06-01 | 2023-11-07 |
| Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery Ciprofloxacin, Azithromycin - Dysentery, Shigella, Shigellosis | Phase 4 | Completed | Oxford University Clinical Research Unit, Vietnam | 364 | 2019-12-11 | 2023-06-07 |
| Comparison of Two Drugs Regimen in Treatment of Complicated Typhoid Fever in Children Meropenem Injection, Azithromycin Powder - Typhoid Fever | Phase 4 | Completed | Ziauddin University | 126 | 2019-06-20 | 2021-06-16 |
| PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) Piperacillin/tazobactam, Meropenem - Beta Lactam Resistant Bacterial Infection, Enterobacteriaceae Infections | Phase 4 | Recruiting | Rambam Health Care Campus | 1084 | 2019-05-01 | 2025-08-01 |
| Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae Meropenem, Ertapenem 1000 MG, Piperacillin, Tazobactam 4-0.5G Solution for Injection - Urinary Tract Infections, Enterobacteriaceae Infections | Phase 4 | Suspended | Universidad del Norte | 198 | 2019-04-01 | 2024-12-06 |
| Typhoid Fever: Combined vs. Single Antibiotic Therapy ceftriaxone, ceftriaxone and azithromycin, azithromycin - Typhoid Fever | Phase 4 | Unknown | Sheba Medical Center | 120 | 2013-08-01 | 2014-08-27 |
| Gatifloxacin Versus Ceftriaxone in the Treatment of Enteric Fever Ceftriaxone, Gatifloxacin - Enteric Fever, Typhoid Fever | Phase 4 | Completed | Oxford University Clinical Research Unit, Vietnam | 300 | 2011-09-01 | 2016-10-04 |
| Enterobacteriaceae Producing Extended-spectrum β-lactamases (ESBL) Decolonization Study Decolonization, Placebo (Decolonization) - Enterobacteriaceae Infections | Phase 4 | Completed | University Hospital, Geneva | 58 | 2009-06-01 | 2012-08-07 |
Showing 20 of 28. Sign in to see all of them.
Typhoid Fever (15) · Escherichia coli Infections (8) · Paratyphoid Fever (4) · Urinary Tract Infections (4) · Bacteremia (2) · Diarrhea (2) · Cholera (1) · Dysentery (1) · Dysentery, Bacillary (1) · Granulomatosis with Polyangiitis (1) · Lung Diseases, Obstructive (1) · Malaria (1) · Measles (1) · Mumps (1)
Bacterial Infections (28) · Bacterial Infections and Mycoses (28) · Gram-Negative Bacterial Infections (28) · Infections (28) · Salmonella Infections (14) · Male Urogenital Diseases (5) · Urogenital Diseases (5) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Pathological Conditions, Signs and Symptoms (4) · Urologic Diseases (4) · Inflammation (2) · Lung Diseases (2) · Pathologic Processes (2)
Meropenem (6) · Azithromycin (5) · Vi polysaccharide vaccine, typhoid (4) · Hepatitis A Vaccines (3) · Cefixime (2) · Ceftriaxone (2) · Piperacillin, Tazobactam Drug Combination (2) · Amdinocillin Pivoxil (1) · Cholera Vaccines (1) · Ciprofloxacin (1) · Control Groups (1) · Cryoelectron Microscopy (1) · Cryosurgery (1) · Cryotherapy (1) · Dukoral (1)
International Vaccine Institute (6) · Oxford University Clinical Research Unit, Vietnam (3) · Rambam Health Care Campus (2) · CSA Medical, Inc. (1) · Centers for Disease Control and Prevention (1) · Christian Medical College, Vellore, India (1) · Helsinki University Central Hospital (1) · Hospital Mutua de Terrassa (1) · Indus Hospital and Health Network (1) · Medical University of Vienna (1) · Sheba Medical Center (1) · Sheikh Zayed Medical College (1) · Swiss Paraplegic Research, Nottwil (1) · Universidad del Norte (1) · University Hospital, Geneva (1)
Pakistan (4) · Nepal (3) · China (2) · Finland (2) · India (2) · Israel (2) · Switzerland (2) · United States (2) · Vietnam (2) · Austria (1) · Canada (1) · Colombia (1) · Democratic Republic of the Congo (1) · Ghana (1) · Kenya (1)
Florian Marks, PhD (2) · Mical Paul, MD (2) · Noa Eliakim-Raz, MD (2) · Roni Bitterman, MD (2) · Alaa Atamna, MD (1) · Andres F Estupinan Bohorquez, MD (1) · Anu Kantele, MD, PhD (1) · Buddha Basnyat, MBBS,Msc,MD (1) · Buddha Basnyat, MD (1) · Canh G Do, MD (1) · Cristina Mussini, MD (1) · Dafna Yahav, MD (1) · Diego F Viasus Perez, MD. PhD. (1) · Dong Baiqing, MD (1) · Eli Schwartz, MD, DTMH (1)
PMID 10348767, PMID 17145784, PMID 18493312, PMID 19625715, PMID 19684008, PMID 22718054, PMID 23719234, PMID 26809813, PMID 29684022, PMID 33558347, PMID 34607600, PMID 35097222, PMID 40229352, PMID 41276263, PMID 42624818
2019 (1), 2023 (1)