5 completed, 3 recruiting, 2 not yet recruiting, 1 terminated. 6 Phase 4, 3 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 4, Recruiting 2 |
| Phase 3 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Terminated 1 |
Follow Amdinocillin Pivoxil: new trials by email Literature Review of Amdinocillin Pivoxil trials Research Report on Amdinocillin Pivoxil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prediction and Prevention of Bloodstream Infections After Kidney Transplantation Pivmecillinam, Placebo - Kidney Transplant Infection, Bloodstream Infection | Phase 3 | Not yet recruiting | Susanne Dam Nielsen, MD, DMSc | 180 | 2027-01-01 | 2026-10-16 |
| A Study to Investigate Pivmecillinam Versus Nitrofurantoin in Female Adolescents 12 to Less Than 18 Years of Age With Uncomplicated Urinary Tract Infection Pivya (Pivmecillinam 185 mg), Nitrofurantoin 100 mg (nitrofurantoin monohydrate/macrocrystalline capsule) - Uncomplicated Urinary Tract Infections | Phase 2 | Not yet recruiting | Alembic Therapeutics | 100 | 2026-10-24 | 2026-10-13 |
| Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care Pivmecillinam, Standard of Care (Investigator Choice) - Febrile Urinary Tract Infection | Phase 4 | Recruiting | Uppsala University | 560 | 2025-12-01 | 2025-12-17 |
| Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis Pivmecillinam, Amoxicillin clavulanic acid, Amoxicillin - Cystectomy, Bladder Cancer Requiring Cystectomy | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 248 | 2025-01-07 | 2025-01-09 |
| Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs Pivmecillinam and amoxicillin/clavulanic acid, Standard treatment, ciprofloxacin, trimethoprim/sulfamethoxazole or ertapenem depending on susceptibility - Urinary Tract Infections, Bacteremia | Phase 3 | Recruiting | Lund University | 330 | 2023-05-29 | 2023-08-28 |
| Clinical Trial of Pivmecillinam Hydrochloride Tablets in the Treatment of Uncomplicated Urinary Tract Infection Pivmecillinam hydrochloride tablets, Fosfomycin Tromethamine Granules - Uncomplicated Urinary Tract Infection | Phase 3 | Completed | Benova (Tianjin) Innovative medicine Research Co., Ltd. | 299 | 2022-09-29 | 2024-04-17 |
| Clinical Effectiveness and Bacteriological Eradication of 4 Short-course Antibiotics for Uncomplicated UTIs in Women. Fosfomycin Trometamol Salt, Nitrofurantoin, Pivmecillinam - Urinary Tract Infections | Phase 4 | Completed | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 1000 | 2021-11-02 | 2025-09-08 |
| Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy. Ciprofloxacin, Trimethoprim/Sulfamethoxazole, Fosfomycin - Complication, Infection | Phase 4 | Completed | Radboud University Medical Center | 1538 | 2018-04-03 | 2022-05-10 |
| Treating Pyelonephritis an Urosepsis With Pivmecillinam pivmecillinam - Pyelonephritis, Urinary Tract Infections | Phase 4 | Completed | Sykehuset i Vestfold HF | 53 | 2017-09-29 | 2020-04-22 |
| Mecillinam for Treatment of Genital Chlamydia Infection Pivmecillinamhydrochlorid - Chlamydia Trachomatis Infection, Chlamydial Urethritis | Phase 2 | Terminated | Oslo University Hospital | 20 | 2014-03-01 | 2015-06-19 |
| Ibuprofen Versus Mecillinam for Uncomplicated Cystitis Ibuprofen, Mecillinam - Acute Cystitis (Excl in Pregnancy) | Phase 4 | Completed | University of Oslo | 383 | 2013-04-01 | 2017-11-06 |
Urinary Tract Infections (5) · Infections (2) · Bacteremia (1) · Bacteriuria (1) · Escherichia coli Infections (1) · Genital Diseases, Male (1) · Prostatic Neoplasms (1) · Pyelonephritis (1) · Sepsis (1) · Urethritis (1)
Alembic Therapeutics (1) · Benova (Tianjin) Innovative medicine Research Co., Ltd. (1) · Copenhagen University Hospital, Rigshospitalet (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Lund University (1) · Oslo University Hospital (1) · Radboud University Medical Center (1) · Susanne Dam Nielsen, MD, DMSc (1) · Sykehuset i Vestfold HF (1) · University of Oslo (1) · Uppsala University (1)
Norway (4) · Denmark (2) · Sweden (2) · China (1) · Netherlands (1) · Spain (1) · United States (1)
Anne Olaug Olsen, MD, PhD (1) · Heiman Wertheim, Prof. dr. (1) · Oskar Ljungquist, MD, PhD. (1) · Rosa Morros, MD PhD (1) · Tore Stenstad, MD, PhD (1) · Xiangdong Yang, PhD (1)
PMID 25516016, PMID 27165786, PMID 29763434, PMID 32868350, PMID 34824124, PMID 35590284, PMID 36419331, PMID 37101774, PMID 37660037, PMID 39698942, PMID 40722189, PMID 42026010
2016 (1), 2023 (1)