8 completed, 1 recruiting. 4 Phase 4, 2 Not applicable, 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 4 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow Paratyphoid Fever: new trials by email Literature Review of Paratyphoid Fever trials Research Report on Paratyphoid Fever
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults TYP04A Low Dose without Alum investigational vaccine, TYP04B Full Dose without Alum investigational vaccine, TYP03A Low Dose with Alum investigational vaccine - Typhoid Fever | Phase 1 | Completed | GlaxoSmithKline | 97 | 2022-11-28 | 2025-01-24 |
| Transcriptomic Responses for the Identification of Pathogens 5-gene transcription signature - Enteric Fever, Acute Febrile Illness | Recruiting | University of Sheffield | 2000 | 2022-05-02 | 2025-03-03 | |
| Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge Study Salmonella Typhi, Salmonella Paratyphi - Typhoid Fever, Paratyphoid Fever | Not applicable | Completed | University of Oxford | 125 | 2014-12-01 | 2022-06-02 |
| Understanding Paratyphoid Infection Salmonella enterica serovar Paratyphi A (strain NVGH308) - Enteric Fever Caused by Salmonella Enterica Serovar Paratyphi A | Not applicable | Completed | University of Oxford | 80 | 2014-03-01 | 2022-03-14 |
| TY800 Dose Escalation (Typhoid) Ty800, Placebo - Typhoid and Paratyphoid Fevers | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 47 | 2006-02-01 | 2011-06-10 |
| Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever Typhoid Vi vaccine, Hepatitis A vaccine - Typhoid, Paratyphoid Fever | Phase 4 | Completed | International Vaccine Institute | 37673 | 2003-05-01 | 2008-08-26 |
| Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam Typhoid Vi vaccine, Hepatitis A (control) - Typhoid, Paratyphoid Fever | Phase 4 | Completed | International Vaccine Institute | 100742 | 2001-12-01 | 2008-03-13 |
| Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, China Typhoid Vi vaccine, Meningococcal A (control) - Typhoid, Paratyphoid Fever | Phase 4 | Completed | International Vaccine Institute | 96468 | 2001-10-01 | 2008-03-13 |
| Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood Typhoid Vi vaccine, Hepatitis A vaccine - Typhoid, Paratyphoid Fever | Phase 4 | Completed | International Vaccine Institute | 27231 | 2001-10-01 | 2008-08-26 |
Typhoid Fever (9) · Fever (1) · Salmonella Infections (1)
Bacterial Infections (9) · Bacterial Infections and Mycoses (9) · Enterobacteriaceae Infections (9) · Gram-Negative Bacterial Infections (9) · Infections (9) · Salmonella Infections (8) · Body Temperature Changes (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Vi polysaccharide vaccine, typhoid (5) · Hepatitis A Vaccines (3) · Adjuvants, Vaccine (1) · Boostrix (1) · Vaccines (1)
International Vaccine Institute (4) · University of Oxford (2) · GlaxoSmithKline (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · University of Sheffield (1)
India (2) · United Kingdom (2) · Belgium (1) · China (1) · Pakistan (1) · United States (1) · Vietnam (1)
Andrew Pollard, FRCPCH, PhD (1) · Andrew Pollard, MBBS (1) · Canh G Do, MD (1) · Dong Baiqing, MD (1) · Sujit K Bhatttacharya, MD (1) · Thomas Darton (1) · Zulfiqar A Bhutta, MBBS, PhD (1)
PMID 19625715, PMID 26082464, PMID 28158395, PMID 29343684, PMID 31877141, PMID 41587557, PMID 42234814