25 completed. 25 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 25 | Completed 25 |
Follow Endothelial Dysfunction: new trials by email Literature Review of Endothelial Dysfunction trials Research Report on Endothelial Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Novel Therapeutics and Endothelial Dysfunction in T1DM Patients Semaglutide Pen Injector [Ozempic], Empagliflozin 10 MG - Endothelial Dysfunction, Diabetes Mellitus, Type 1 | Phase 4 | Completed | General and Teaching Hospital Celje | 90 | 2021-12-15 | 2023-05-12 |
| Endothelial Injury Mechanism in Elderly Patients Undergoing Major Surgery Dexmedetomidine, Saline - Endothelial Dysfunction, Blood Brain Barrier Defect | Phase 4 | Completed | The First Affiliated Hospital of Anhui Medical University | 464 | 2019-07-01 | 2021-02-10 |
| Functional Assessment of the Infart-related Artery With Bioactive and Polymer-free Coronary Stents (The FUNCOMBO Trial) Stent implantation in the infart-related artery in patients with ST elevation myocardial infarction - Endothelial Dysfunction, Coronary Microvascular Disease | Phase 4 | Completed | Institut d'Investigació Biomèdica de Bellvitge | 60 | 2018-11-05 | 2020-10-26 |
| Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis Methotrexate, Sulfasalazine, Other DMARDs - Rheumatoid Arthritis, Stiffness, Aortic | Phase 4 | Completed | Flinders University | 124 | 2017-10-01 | 2025-02-26 |
| Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments Paroxetine, Placebo oral capsule - Postmenopausal Flushing, Cardiovascular Risk Factor | Phase 4 | Completed | Rio de Janeiro State University | 140 | 2016-03-01 | 2018-04-12 |
| Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI Ticagrelor, Clopidogrel - Myocardial Ischemia, Coronary Artery Disease | Phase 4 | Completed | University Hospital of Limerick | 61 | 2015-07-01 | 2016-03-11 |
| Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28) OctaplasLG®, Fresh frozen plasma - Aortic Aneurysm, Thoracic, Endothelial Dysfunction | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 44 | 2014-11-01 | 2016-12-20 |
| Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension Glibenclamide, Vildagliptin - Type 2 Diabetes Mellitus, Hypertension | Phase 4 | Completed | Dr. José Fernando Vilela-Martin MD PhD | 50 | 2013-07-01 | 2016-08-16 |
| Functional Change in Endothelium After Cardiac cAtheterization, With and Without Music Therapy Music therapy - Coronary Artery Disease, Endothelial Dysfunction | Phase 4 | Completed | Emmanouil Brilakis | 70 | 2012-06-01 | 2013-10-29 |
| The Effect of Cilostazol Compared to Aspirin on Endothelial Function in Acute Cerebral Ischemia Patients Cilostazol 100mg, Aspirin - Ischemic Stroke, Endothelial Dysfunction | Phase 4 | Completed | Ajou University School of Medicine | 80 | 2012-03-01 | 2017-04-17 |
| Effects of Diet-induced Weight Loss in Obese Men Optifast, Conventional diet counseling - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 70 | 2010-12-01 | 2015-07-29 |
| Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men weight loss counselling - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 90 | 2010-07-01 | 2015-07-29 |
| Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men Exercise and diet - Sexual Dysfunction, Endothelial Dysfunction | Phase 4 | Completed | Changi General Hospital | 70 | 2010-07-01 | 2015-07-29 |
| Effects of Magnesium Supplementation on Vascular Structure and Function in Hypertensive Patients magnesium, placebo - Hypertension, Endothelial Dysfunction | Phase 4 | Completed | Rio de Janeiro State University | 52 | 2010-03-01 | 2013-01-07 |
| Correlation Study of Vascular Parameters in Hypertensive Men With Erectile Dysfunction Vardenafil - Erectile Dysfunction, Arterial Hypertension | Phase 4 | Completed | Hospital Universitario Pedro Ernesto | 100 | 2010-01-01 | 2011-04-18 |
| Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury rosuvastatin, atorvastatin 3 days, placebo - Ischemia Reperfusion Injury, Endothelial Dysfunction | Phase 4 | Completed | Radboud University Medical Center | 48 | 2009-09-01 | 2010-04-28 |
| Simvastatin Effect on Inflammation and Endothelial Function After Myocardial Infarction Simvastatin - Myocardial Infarction, Inflammation | Phase 4 | Completed | Brasilia Heart Study Group | 58 | 2008-11-01 | 2011-06-23 |
| Endothelial Effects of Basal Insulin: Detemir Versus Glargine Glargine, Detemir - Type 2 Diabetes, Endothelial Dysfunction | Phase 4 | Completed | University of Padova | 50 | 2008-05-01 | 2010-08-17 |
| Cardiovascular Effects of Chronic Sildenafil in Men With Type 2 Diabetes Sildenafil, Placebo - Diabetes Mellitus, Type 2, Endothelial Dysfunction | Phase 4 | Completed | University of Roma La Sapienza | 59 | 2008-01-01 | 2013-05-08 |
| The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation Atorvastatin, Placebo - Atrial Fibrillation, Arrhythmia | Phase 4 | Completed | Mayo Clinic | 125 | 2007-12-01 | 2014-04-23 |
Showing 20 of 25. Sign in to see all of them.
Inflammation (5) · Diabetes Mellitus, Type 2 (4) · Coronary Artery Disease (3) · Diabetes Mellitus (3) · Hypertension (3) · Multiple Endocrine Neoplasia Type 1 (3) · Obesity (3) · Sexual Dysfunction, Physiological (3) · Atherosclerosis (2) · Myocardial Infarction (2) · Acute Coronary Syndrome (1) · Aortic Aneurysm, Thoracic (1) · Arrhythmias, Cardiac (1) · Arthritis, Rheumatoid (1) · Atrial Fibrillation (1)
Cardiovascular Diseases (13) · Vascular Diseases (12) · Endocrine System Diseases (9) · Nutritional and Metabolic Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (8) · Glucose Metabolism Disorders (6) · Heart Diseases (6) · Metabolic Diseases (6) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Genital Diseases (4) · Myocardial Ischemia (4) · Signs and Symptoms (4) · Urogenital Diseases (4)
Atorvastatin (3) · Rosuvastatin Calcium (2) · Aspirin (1) · Cilostazol (1) · Clopidogrel (1) · Dexmedetomidine (1) · Diet (1) · Exercise (1) · Ezetimibe (1) · Glyburide (1) · Insulin Detemir (1) · Insulin Glargine (1) · Magnesium (1) · Metformin (1) · Methotrexate (1)
Changi General Hospital (3) · Rio de Janeiro State University (2) · Ajou University School of Medicine (1) · Brasilia Heart Study Group (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dr. José Fernando Vilela-Martin MD PhD (1) · Emmanouil Brilakis (1) · Flinders University (1) · General and Teaching Hospital Celje (1) · Hippocration General Hospital (1) · Hospital Universitario Pedro Ernesto (1) · Institut d'Investigació Biomèdica de Bellvitge (1) · Laboratorios Silanes S.A. de C.V. (1) · Mayo Clinic (1) · Odense University Hospital (1)
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Alin O Stirban, Dr (1) · Andrea Lenzi, MD, PhD (1) · Andrei C Sposito, MD, PhD (1) · Andrej Janez, prof PhD (1) · Angelo Avogaro, M.D. (1) · Ciciliana MZ Rech (1) · Dimitris Tousoulis (1) · Emmanouil S Brilakis, MD, PhD (1) · Jakob Stensballe, MD, PhD (1) · Ji Man Hong (1) · Joan J Khoo, MRCP (1) · Joan Khoo, MBBS,MRCP (1) · Joan Khoo, MRCP (1) · Jose F Vilela-Martin, MD PhD (1)
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2015 (1)