9 completed, 4 unknown, 2 recruiting, 1 not yet recruiting. 18 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Completed 9, Unknown 4, Recruiting 2, Not yet recruiting 1, Suspended 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 3, Recruiting 1, Unknown 1 |
Follow Encephalomyelitis: new trials by email Literature Review of Encephalomyelitis trials Research Report on Encephalomyelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1 Study Evaluating the Safety, Tolerability, and Immunogenicity of V4020 Vaccine in Healthy Volunteers V4020 - Venezuelan Equine Encephalitis, Venezuelan Equine Encephalitis Virus Infection | Phase 1 | Not yet recruiting | Medigen, Inc. | 39 | 2025-08-15 | 2025-07-28 |
| Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Lumbrokinase - Long Covid, Post-treatment Lyme Disease Syndrome | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 120 | 2024-10-09 | 2026-03-13 |
| Effect of Stellate Ganglion Block on ME/CFS Bupivacaine Injection - Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome | Phase 1 | Completed | Neuroversion, Inc. | 10 | 2023-03-15 | 2024-12-06 |
| Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome Heart Rhythm Biofeedback, Hydrogen Water, Combined treatment: Heart rhythm biofeedback plus hydrogen water - Chronic Fatigue Syndrome | Phase 1 | Unknown | Stony Brook University | 39 | 2022-05-23 | 2022-05-31 |
| Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes. [Zr-89]Oxine-labeled leukocytes PET/MRI - Fibromyalgia, Chronic Fatigue Syndrome | Phase 1 | Suspended | University of Alabama at Birmingham | 120 | 2021-10-05 | 2026-06-02 |
| Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects MVA-BN-WEV Dose 1, MVA-BN-WEV Dose 2, MVA-BN-WEV Dose 3 - Equine Encephalitis | Phase 1 | Completed | Bavarian Nordic | 45 | 2019-10-07 | 2020-08-20 |
| VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy Adults VRC-WEVVLP073-00-VP, VRC-GENMIX083-AL-VP - Venezuelan Equine Encephalitis, Western Equine Encephalitis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2019-04-02 | 2021-03-24 |
| Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714. DPA-714 PET/MRI - Fibromyalgia, Chronic Fatigue Syndrome | Phase 1 | Recruiting | University of Alabama at Birmingham | 120 | 2019-02-03 | 2026-06-02 |
| Clinical Trial to Investigate CT38 in the Treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome CT38 - Myalgic Encephalomyelitis, Chronic Fatigue Syndrome | Phase 1 / Phase 2 | Completed | LUCINDA BATEMAN, MD | 17 | 2018-07-23 | 2020-05-12 |
| Venezuelan Equine Encephalitis Monovalent Virus-Like Particle Vaccine Vaccinations on Day 0, Day 28, and Day 140 - Encephalitis, Encephalitis, Viral | Phase 1 | Unknown | SRI International | 48 | 2018-07-17 | 2021-02-23 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Efficacy of BC 007 in Healthy Subjects BC 007, NaCl 0.9 % - Healthy Volunteers | Phase 1 | Completed | Berlin Cures GmbH | 74 | 2016-08-01 | 2018-07-18 |
| Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients Normal Saline, Oral Rehydration Solution - Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | Phase 1 | Unknown | New York Medical College | 45 | 2016-02-01 | 2021-06-10 |
| Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy Volunteers Venezuelan Equine Encephalitis Virus DNA Vaccine Candidate, 0.9% saline placebo - Venezuelan Equine Encephalitis Virus Infection | Phase 1 | Completed | Ichor Medical Systems Incorporated | 42 | 2013-12-01 | 2015-08-26 |
| Treatment of Chronic Fatigue Syndrome (CFS) With Iodinated Activated Charcoal (IodoCarb®) IodoCarb (r), Placebo - Chronic Fatigue Syndrome | Phase 1 / Phase 2 | Unknown | PharmaLundensis AB | 40 | 2013-02-01 | 2013-02-15 |
| Behavioral Insomnia Therapy With Chronic Fatigue Syndrome Cognitive Behavioral Therapy, Usual Care for Chronic Fatigue Syndrome (Active Control Group) - Chronic Fatigue Syndrome, Behavioral Therapy Targeted to Sleep Problems | Phase 1 / Phase 2 | Completed | Duke University | 24 | 2007-09-01 | 2013-03-01 |
| Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV) valganciclovir - Chronic Fatigue Syndrome | Phase 1 / Phase 2 | Completed | Stanford University | 30 | 2007-05-01 | 2022-05-27 |
| Autonomic Nervous System and Chronic Fatigue Syndrome Autonomic Function Testing, Saline infusions, L-NMMA trimethaphan - Chronic Fatigue Syndrome, Orthostatic Intolerance | Phase 1 | Completed | Vanderbilt University | 170 | 2007-04-01 | 2017-01-18 |
| Safety, Tolerability and Immunogenicity of the Venezuelan Equine Encephalitis (VEE) Attenuated Live-Virus Vaccine VEE 3526 - Venezuelan Equine Encephalitis | Phase 1 | Withdrawn | DynPort Vaccine Company LLC, A GDIT Company | 2005-07-01 | 2015-09-18 |
Fatigue Syndrome, Chronic (12) · Encephalomyelitis, Venezuelan Equine (5) · Orthostatic Intolerance (3) · Alphavirus Infections (2) · Encephalomyelitis, Equine (2) · Fibromyalgia (2) · Multiple Sclerosis (2) · Postural Orthostatic Tachycardia Syndrome (2) · Brain Diseases (1) · Cardiomyopathies (1) · Central Nervous System Diseases (1) · Central Nervous System Infections (1) · Central Nervous System Viral Diseases (1) · Encephalitis (1) · Encephalitis, Viral (1)
Neuroinflammatory Diseases (18) · Nervous System Diseases (17) · Chronic Disease (12) · Disease Attributes (12) · Muscular Diseases (12) · Musculoskeletal Diseases (12) · Neuromuscular Diseases (12) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Infections (8) · Vector Borne Diseases (7) · Virus Diseases (7) · Arbovirus Infections (6) · Encephalitis, Arbovirus (6)
Bupivacaine (1) · Cognitive Behavioral Therapy (1) · Methyldopa (1) · ORALIT (1) · Saline Solution (1) · Sodium Chloride (1) · Valganciclovir (1) · Water (1) · World Health Organization oral rehydration solution (1) · aluminum sulfate (1) · lumbrokinase (1)
University of Alabama at Birmingham (2) · Bavarian Nordic (1) · Berlin Cures GmbH (1) · Duke University (1) · DynPort Vaccine Company LLC, A GDIT Company (1) · Icahn School of Medicine at Mount Sinai (1) · Ichor Medical Systems Incorporated (1) · LUCINDA BATEMAN, MD (1) · Medigen, Inc. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Neuroversion, Inc. (1) · New York Medical College (1) · PharmaLundensis AB (1) · SRI International (1) · Stanford University (1)
United States (16) · Germany (1) · Sweden (1)
Anders Luts, MD, PhD (1) · Andrew Krystal, M.D. (1) · Angela Sinn, Dr. (1) · Carlos Fierro, MD (1) · David Putrino, PhD, PT (1) · Deborah L Duricka, PhD (1) · Grace Chen, MD (1) · Italo Biaggioni, MD (1) · Jonathan McConathy, MD,PhD (1) · Jose G Montoya, MD (1) · Julie E Ledgerwood, DO (1) · Lucinda Bateman, MD (1) · Mark Mayo (1) · Marvin S. Medow, Ph.D. (1)
PMID 21906029, PMID 23959519, PMID 27206386, PMID 32222912, PMID 34539356, PMID 35568049, PMID 37326674, PMID 38494412, PMID 42825819
2015 (1), R01NS109529 (1), R21NR010539 (1), R21NS094644 (1)