7 completed, 6 unknown, 1 recruiting, 1 terminated. 15 Phase 2, 4 Phase 1, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 7, Unknown 6, Recruiting 1, Terminated 1 |
| Phase 1 | 4 | Unknown 3, Completed 1 |
| Phase 3 | 4 | Completed 2, Terminated 1, Unknown 1 |
Follow Diverticular Diseases: new trials by email Literature Review of Diverticular Diseases trials Research Report on Diverticular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis MBK-01 - Diverticulitis, Diverticulitis of Sigmoid | Phase 2 | Recruiting | Mikrobiomik Healthcare Company S.L. | 81 | 2025-04-03 | 2025-06-05 |
| Transversus Abdominis Plane Blocks With and Without Dexamethasone Dexamethasone - Colorectal Disorders, Regional Anesthesia Morbidity | Phase 1 / Phase 2 | Unknown | University of Saskatchewan | 60 | 2022-09-01 | 2023-12-07 |
| Combination of Curcumin and Berberine Therapy in the Treatment of Post Acute Diverticulitis (SUDD) Curcumin-Berberine (coptis), Placebo - Diverticulitis | Phase 2 | Unknown | Dr. Adi Lahat | 40 | 2022-08-14 | 2023-12-08 |
| Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. Rifaximin delayed released 400mg Tablet, Placebo - Diverticulitis | Phase 2 / Phase 3 | Terminated | Alfasigma S.p.A. | 193 | 2018-07-02 | 2021-10-20 |
| The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery Near-infrared ICG fluorescence imaging, Traditional bowel anastomosis, FireFly™ - Colon Neoplasms, Rectal Neoplasms | Phase 2 / Phase 3 | Unknown | Acibadem University | 102 | 2015-11-01 | 2015-11-24 |
| Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery Laparoscopic surgery, Skin sealant - Complications of Surgical Procedures, Surgical Site Infection | Phase 2 | Unknown | First Affiliated Hospital, Sun Yat-Sen University | 100 | 2015-02-01 | 2015-08-13 |
| Single-port Versus Conventional Laparoscopic Colorectal Surgery Single-port access surgery, Conventional Laparoscopic Access - Colorectal Cancer, Inflammatory Bowel Disease | Phase 1 / Phase 2 | Unknown | North Tees and Hartlepool NHS Foundation Trust | 50 | 2014-01-01 | 2016-03-24 |
| Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program Spinal analgesia, Patient Control Analgesia (PCA) Morphine - Colon Cancer, Inflammatory Bowel Diseases | Phase 1 / Phase 2 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 40 | 2010-10-01 | 2011-11-28 |
| Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine Lidocaine, Thoracic epidural block - Colon Cancer, Inflammatory Bowel Diseases | Phase 2 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 60 | 2009-06-01 | 2011-11-28 |
| Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery epidural, PCA, Spinal - Neoplasm, Diverticular Disease | Phase 1 / Phase 2 | Unknown | Minimal Access Therapy Training Unit | 99 | 2007-12-01 | 2008-09-05 |
| Asacol Acute Diverticulitis(DIVA)Study Mesalamine, Probiotic, Placebo - Diverticulitis | Phase 2 | Completed | Warner Chilcott | 117 | 2007-11-01 | 2013-04-22 |
| Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation Hartmann's operation, Primary anastomosis - Surgery, Diverticulitis | Phase 2 / Phase 3 | Completed | University of Zurich | 62 | 2006-05-01 | 2012-05-28 |
| Mesalamine for Uncomplicated Diverticular Disease: a Randomized, Double-blind, Placebo-controlled Study Mesalamine, Placebo - Colonic Diverticulosis | Phase 2 | Completed | Dr. Falk Pharma GmbH | 123 | 2002-05-01 | 2016-01-21 |
| Hartmann vs R/A in Peritonitis by Perforated Diverticulitis Primary sigmoid resection with end colostomy (Hartmann), Primary sigmoid resection and immediate anastomosis with diverting stoma (PRA) - Peritonitis Caused by Perforated Left-sided Colon Diverticulitis | Phase 2 / Phase 3 | Completed | Ente Ospedaliero Ospedali Galliera | 100 | 2000-01-01 | 2010-11-15 |
| End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study Niti CAR - Colorectal Cancer, Diverticulitis | Phase 2 | Completed | Niti Medical Technologies Ltd. | 2011-06-29 |
Diverticulitis (9) · Inflammatory Bowel Diseases (5) · Colorectal Neoplasms (4) · Colonic Neoplasms (3) · Agnosia (2) · Diverticulum (2) · Neoplasms (2) · Anastomotic Leak (1) · Crohn Disease (1) · Diverticulosis, Colonic (1) · Gastrointestinal Stromal Tumors (1) · Intestinal Perforation (1) · Pain, Postoperative (1) · Postoperative Complications (1)
Digestive System Diseases (15) · Gastroenteritis (15) · Gastrointestinal Diseases (15) · Intestinal Diseases (9) · Colonic Diseases (8) · Digestive System Neoplasms (7) · Gastrointestinal Neoplasms (7) · Intestinal Neoplasms (7) · Neoplasms (7) · Neoplasms by Site (7) · Pathological Conditions, Signs and Symptoms (6) · Rectal Diseases (5) · Pathologic Processes (4) · Colorectal Neoplasms (3)
Mesalamine (2) · Passive Cutaneous Anaphylaxis (2) · Anesthesia, Spinal (1) · Anti-Bacterial Agents (1) · Colectomy (1) · Coptis extract (1) · Dexamethasone (1) · Fecal Microbiota Transplantation (1) · Indocyanine Green (1) · Injections, Epidural (1) · Laparoscopy (1) · Lidocaine (1) · Morphine (1) · Nutrition Assessment (1) · Probiotics (1)
McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Acibadem University (1) · Alfasigma S.p.A. (1) · Dr. Adi Lahat (1) · Dr. Falk Pharma GmbH (1) · Ente Ospedaliero Ospedali Galliera (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Mikrobiomik Healthcare Company S.L. (1) · Minimal Access Therapy Training Unit (1) · Niti Medical Technologies Ltd. (1) · North Tees and Hartlepool NHS Foundation Trust (1) · University of Saskatchewan (1) · University of Zurich (1) · Warner Chilcott (1)
Canada (3) · United Kingdom (3) · Germany (2) · Italy (2) · Spain (2) · Belgium (1) · China (1) · France (1) · Israel (1) · Netherlands (1) · Switzerland (1) · Turkey (Türkiye) (1) · United States (1)
Adi Lahat-Zok, MD (1) · Alberto Serventi (1) · Ana Balske, MD, PhD (1) · Bilgi Baca, MD,Prof.Dr. (1) · David N Ginther, MD (1) · Franco Carli, Professor (1) · Gian Andrea Binda (1) · Mingkwan Wongyingsinn, Fellow (1) · Roberto Bergamaschi, MD (1) · Stefan Breitenstein, MD (1) · Tim Rockall, FRCS (1) · Wolfgang Kruis, MD (1)
PMID 21519309, PMID 23095627, PMID 23414061, PMID 23426454, PMID 24566744, PMID 25451666
2017 (1), 2023 (1)