4 unknown, 3 completed, 3 recruiting, 1 withdrawn. 3 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Unknown 2 |
| Phase 3 | 2 | Unknown 2 |
| Phase 4 | 1 | Recruiting 1 |
Follow Disc Disease: new trials by email Literature Review of Disc Disease trials Research Report on Disc Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease Cervical Fusion (ZetaFuse™ Bone Graft) - Radiculopathy, Cervical, Myelopathy Cervical | Not applicable | Recruiting | Zetagen Therapeutics, Inc | 10 | 2026-09-01 | 2025-04-24 |
| Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF Dexamethasone, Normal saline - Spinal Stenosis Lumbar, Disc Degeneration | Phase 4 | Recruiting | Potsawat Surabotsopon | 60 | 2024-05-01 | 2025-09-08 |
| The Effectiveness of Lumber Regression Technique on Disc Bulge Randomized Control Trial Advanced Physiotherapy, Conventional Physiotherapy Techniques - Disc Disease | Not applicable | Unknown | Superior University | 22 | 2023-10-01 | 2024-08-12 |
| Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment OP-Tracker App - Disc Disease, Instabilities Lumbar | Recruiting | Cantonal Hospital of St. Gallen | 400 | 2023-06-12 | 2026-03-19 | |
| Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs Bone Marrow Concentrate - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Stem Cures | 80 | 2018-11-21 | 2020-09-22 |
| Fibrin for Chronic Multi-level Discogenic Low Back Pain Fibrin sealant - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Pauza, Kevin, MD | 400 | 2018-06-11 | 2020-11-09 |
| Predictors of Clinical Response After Interlaminar Cervical Epidural Steroid Injection for Cervical Radiculopathy Radiculopathy, Cervical Region, Neck Pain | Completed | Mersin University | 107 | 2018-01-01 | 2026-04-17 | |
| Galeazzi Spine Surgery RegistryGaleazzi Spine Registry: Prospective Study for Clinical Monitoring Spine Surgery - Patients Undergoing Spine Surgery, Scoliosis | Unknown | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 10000 | 2015-11-10 | 2020-01-27 | |
| Retrospective Study on the Evaluation of Intra-disc Infiltration in the Active Disc Disease Disc Disease | Withdrawn | Fondation Hôpital Saint-Joseph | 2015-05-01 | 2017-02-17 | ||
| Outcome After Lumbar Epidural Steroid Injection Disc Disease | Completed | Scuderi, Gaetano J., M.D. | 26 | 2008-03-01 | 2010-03-02 | |
| Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity Methylprednisolone - Disc Disease | Not applicable | Completed | Northern Orthopaedic Division, Denmark | 200 | 2001-05-01 | 2014-09-15 |
Radiculopathy (5) · Intervertebral Disc Degeneration (4) · Low Back Pain (2) · Spinal Stenosis (2) · Alzheimer Disease (1) · Aneurysm (1) · Brain Neoplasms (1) · Neck Pain (1) · Nervous System Malformations (1) · Sciatica (1) · Scoliosis (1) · Spinal Cord Diseases (1) · Spinal Fractures (1)
Nervous System Diseases (7) · Bone Diseases (5) · Musculoskeletal Diseases (5) · Neuromuscular Diseases (5) · Peripheral Nervous System Diseases (5) · Spinal Diseases (5) · Neurologic Manifestations (3) · Pain (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Back Pain (2) · Central Nervous System Diseases (2) · Back Injuries (1) · Brain Diseases (1) · Cardiovascular Diseases (1)
Dexamethasone (1) · Fibrin Tissue Adhesive (1) · Methylprednisolone (1) · Saline Solution (1)
Cantonal Hospital of St. Gallen (1) · Fondation Hôpital Saint-Joseph (1) · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio (1) · Mersin University (1) · Northern Orthopaedic Division, Denmark (1) · Pauza, Kevin, MD (1) · Potsawat Surabotsopon (1) · Scuderi, Gaetano J., M.D. (1) · Stem Cures (1) · Superior University (1) · Zetagen Therapeutics, Inc (1)
United States (2) · Australia (1) · Denmark (1) · France (1) · Italy (1) · Pakistan (1) · Switzerland (1) · Thailand (1) · Turkey (Türkiye) (1)
Gaetano J Scuderi, MD (1) · Kevin Pauza, MD (1) · Sairam Atluri, MD (1) · Sten Rasmussen, M.D.Sci. (1)
PMID 16757774, PMID 21799397, PMID 24464507, PMID 25932600, PMID 26213843, PMID 27683674, PMID 29337717, PMID 31587982, PMID 37000218, PMID 40142224