8 completed, 3 not yet recruiting, 1 active not recruiting, 1 recruiting. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 8, Not yet recruiting 3, Active not recruiting 1, Recruiting 1, Unknown 1 |
Follow Diabetic Kidney Disease: new trials by email Literature Review of Diabetic Kidney Disease trials Research Report on Diabetic Kidney Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Finerenone in African American Veterans With Diabetic Kidney Disease Finerenone 10 MG, Empagliflozin 10 MG - Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Washington D.C. Veterans Affairs Medical Center | 30 | 2026-10-01 | 2026-08-21 |
| Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study Finerenone, Spironolactone (drug) - Heart Failure, Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Hospital de Messejana Dr. Carlos Alberto Studart Gomes | 60 | 2026-04-01 | 2026-05-13 |
| Clinical Trial of Keluoxin Capsules in the Treatment of Diabetic Kidney Disease with Diabetic Retinopathy Keluoxin Capsules, Keluoxin Capsule Simulants, Irbesartan - Diabetic Kidney Disease, Diabetic Retinopathy | Phase 4 | Not yet recruiting | Chinese PLA General Hospital | 460 | 2024-10-01 | 2024-10-28 |
| Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes dapagliflozin, ACE inhibitor - Diabetic Kidney Disease, Type 1 Diabetes | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 54 | 2024-07-01 | 2024-08-01 |
| Mechanism of SGLT2 Inhibition in the Kidney SGLT2 inhibitor - Type 2 Diabetes, Diabetic Kidney Disease | Phase 4 | Recruiting | University of Michigan | 20 | 2024-01-01 | 2026-06-11 |
| DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study Salt-Diet and/or Ertugliflozin, Ertugliflozin 15 mg - Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 41 | 2023-07-03 | 2026-04-15 |
| Basal Plus GLP1-ra on Glycemic Variability in CKD Dulaglutide, Insulin Degludec, Continuous glucose monitor - Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Elaine Chow | 95 | 2022-01-28 | 2024-12-03 |
| Study of Roxadustat's Effect on Anemia in Patients With Diabetic Kidney Disease Roxadustat - Diabetic Kidney Disease, Anemia | Phase 4 | Completed | Second Xiangya Hospital of Central South University | 124 | 2021-11-02 | 2026-01-26 |
| Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study. Ertugliflozin 15 mg - Type 2 Diabetes Mellitus, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 40 | 2020-12-10 | 2023-05-01 |
| Renohemodynamic Effects of Combined empagliflOzin and LosARtan Empagliflozin 10 MG, Losartan 50Mg Tab, Placebo - Diabetes Mellitus, Type 2, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 24 | 2020-11-04 | 2021-10-08 |
| Pentoxifylline in Diabetic Kidney Disease Pentoxifylline, Placebo - Diabetic Kidney Disease | Phase 4 | Active not recruiting | VA Office of Research and Development | 2376 | 2019-11-18 | 2026-04-13 |
| Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes sodium bicarbonate - Type 1 Diabetes, Diabetic Nephropathy | Phase 4 | Completed | University of Colorado, Denver | 45 | 2017-01-01 | 2026-06-17 |
| Antiproteinuric Effects of Liraglutide Treatment Liraglutide, placebo - Diabetic Kidney Disease | Phase 4 | Completed | Steno Diabetes Center Copenhagen | 32 | 2015-04-01 | 2016-08-10 |
| Effect of LIXIsenatide on the Renal System Lixisenatide, Insulin glulisine - Diabetic Kidney Disease, Diabetic Nephropathy | Phase 4 | Completed | Amsterdam UMC, location VUmc | 40 | 2014-09-01 | 2016-04-29 |
Diabetic Nephropathies (14) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 2 (3) · Diabetes Mellitus, Type 1 (2) · Renal Insufficiency, Chronic (2) · Anemia (1) · Cardio-Renal Syndrome (1) · Diabetic Retinopathy (1) · Heart Failure (1) · Hyperkalemia (1) · Hypertension (1)
Diabetes Complications (14) · Endocrine System Diseases (14) · Female Urogenital Diseases (14) · Female Urogenital Diseases and Pregnancy Complications (14) · Kidney Diseases (14) · Male Urogenital Diseases (14) · Urogenital Diseases (14) · Urologic Diseases (14) · Diabetes Mellitus (10) · Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10) · Glucose Metabolism Disorders (9) · Cardiovascular Diseases (3) · Autoimmune Diseases (2) · Chronic Disease (2)
empagliflozin (2) · ertugliflozin (2) · finerenone (2) · Angiotensin-Converting Enzyme Inhibitors (1) · Canagliflozin (1) · Irbesartan (1) · Liraglutide (1) · Losartan (1) · Pentoxifylline (1) · Pharmaceutical Preparations (1) · Sodium Bicarbonate (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · Spironolactone (1) · dapagliflozin (1) · dulaglutide (1)
Amsterdam UMC, location VUmc (4) · Chinese PLA General Hospital (1) · Elaine Chow (1) · Hospital de Messejana Dr. Carlos Alberto Studart Gomes (1) · Second Xiangya Hospital of Central South University (1) · Steno Diabetes Center Copenhagen (1) · The First Affiliated Hospital with Nanjing Medical University (1) · University of Colorado, Denver (1) · University of Michigan (1) · VA Office of Research and Development (1) · Washington D.C. Veterans Affairs Medical Center (1)
Netherlands (4) · United States (4) · China (2) · Denmark (1) · Hong Kong (1)
Daniel van Raalte, MD PhD (1) · David J Leehey (1) · Lin Sun, doctor (1) · Markus Bitzer, MD (1) · Mei Zhang (1) · Peter Rossing, MD (1) · Sabyasachi Sen, MD, PhD (1)
PMID 27753201, PMID 28449402, PMID 34400461, PMID 37752566, PMID 37916745, PMID 38449081, PMID 38682786, PMID 38770818, PMID 39963952, PMID 42216096
2014 (1)