58 completed, 21 unknown, 19 recruiting, 13 not yet recruiting. 37 Phase 2, 30 Not applicable, 16 Phase 3, 14 Phase 4, 10 Phase 1.
Follow Diabetic Kidney Disease: new trials by email Literature Review of Diabetic Kidney Disease trials Research Report on Diabetic Kidney Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Predictors and Therapeutic Gaps in CKM Syndrome Among Adults With Type 2 Diabetes clinical and laboratory CKM staging evaluation - Type 2 Diabetes Mellitus, Cardiovascular-Kidney-Metabolic Syndrome | Not yet recruiting | Assiut University | 231 | 2026-10-20 | 2026-10-02 | |
| Role of Finerenone in African American Veterans With Diabetic Kidney Disease Finerenone 10 MG, Empagliflozin 10 MG - Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Washington D.C. Veterans Affairs Medical Center | 30 | 2026-10-01 | 2026-08-21 |
| Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney Disease Diabetic Kidney Disease, Diabetic Nephropathies | Not yet recruiting | Assiut University | 120 | 2026-09-01 | 2026-08-19 | |
| Evaluating the Effectiveness of a Smart Screening and Tiered Management Tool for Diabetic Kidney Disease in Primary Care: A Cluster Randomized Trial Intervention Name Clinical decision support system for diabetic kidney disease (DKD-CDSS), Routine guideline-based diabetes management - Type 2 Diabetes Mellitus, Diabetic Kidney Disease | Not applicable | Not yet recruiting | First Affiliated Hospital of Chongqing Medical University | 3000 | 2026-07-30 | 2026-07-16 |
| Finerenone for the Treatment of Type 2 Diabetes-Related Kidney Disease: Efficacy Observation and Related Factor Analysis Finerenone - Type 2 Diabetes Mellitus, Diabetic Kidney Disease | Not yet recruiting | First Affiliated Hospital of Chongqing Medical University | 425 | 2026-07-30 | 2026-07-21 | |
| Effect of Chinese Herbal Medicine on Renal Function in Diabetic Kidney Disease Chinese herbal formula DKD-1 - Diabetic Kidney Disease | Not applicable | Not yet recruiting | China Medical University Hospital | 66 | 2026-06-11 | 2026-06-18 |
| Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease MTX-439, Placebo - Healthy Adult Participants, Diabetic Kidney Disease | Phase 1 | Recruiting | Mediar Therapeutics | 88 | 2026-05-19 | 2026-06-29 |
| Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study Finerenone, Spironolactone (drug) - Heart Failure, Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Hospital de Messejana Dr. Carlos Alberto Studart Gomes | 60 | 2026-04-01 | 2026-05-13 |
| Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual Care Usual care for diabetic kidney disease management without primary care provider., Pharmacist-led validated diabetic kidney disease decision support algorithm. - Diabetic Kidney Disease, Type 2 Diabetes | Not applicable | Recruiting | Nova Scotia Health Authority | 120 | 2026-03-01 | 2026-03-18 |
| Gut Microbiota and Serum Metabolites as Predictors of Glycemic Variability and Outcomes in Diabetic Kidney Disease Diabetic Kidney Disease | Not yet recruiting | Eighth Affiliated Hospital, Sun Yat-sen University | 270 | 2026-02-01 | 2026-01-20 | |
| Immune System in Diabetic Kidney Disease Diabetes, Diabetic Kidney Disease | Enrolling by invitation | University Medical Centre Ljubljana | 90 | 2025-12-01 | 2026-02-23 | |
| Formoterol in Diabetes Formoterol furmarate (20 μg) - Diabetic Nephropathies, Diabetic Kidney Disease | Phase 2 | Recruiting | Medical University of South Carolina | 120 | 2025-12-01 | 2026-02-05 |
| Oxygen Therapy in Diabetic Kidney Disease Oxygen Therapy - Diabetic Kidney Disease | Not applicable | Not yet recruiting | Assiut University | 80 | 2025-08-01 | 2025-05-06 |
| P2a Open Label Study to Evaluate 2-HPβCD in Subjects With Diabetic Kidney Disease 2HPβCD - Diabetic Kidney Disease | Phase 2 | Withdrawn | ZyVersa Therapeutics, Inc. | 2025-06-11 | 2025-11-25 | |
| Efficacy and Safety of LC-Z300-01 on Proteinuria in Diabetic Patients Sugar cane polysaccharide, Control - Diabetic Kidney Disease | Not applicable | Not yet recruiting | Shanghai Changzheng Hospital | 60 | 2025-04-01 | 2025-04-02 |
| A Study to Evaluate the Safety, Tolerability, PK and PD of AP303 in DKD Patients AP303 150μg, Placebo 150μg - Diabetic Kidney Disease | Phase 1 | Recruiting | Alebund Pharmaceuticals | 18 | 2025-02-27 | 2025-09-11 |
| Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With Diabetes and Kidney Disease Hypoxia administration study group, Renal clairance study - Diabetes, Diabetic Kidney Disease | Not applicable | Recruiting | Poitiers University Hospital | 30 | 2025-02-13 | 2025-04-09 |
| "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Centers)" Standard Peritoneal Dialysis, Incremental Peritonal Dialysis - Chronic Kidney Disease, Diabetic Kidney Disease | Not applicable | Active not recruiting | Instituto Mexicano del Seguro Social | 100 | 2024-11-01 | 2026-01-13 |
| Revealing Engagement Dynamics Among Diabetic Kidney Disease Patients Diabetic Kidney Disease | Not yet recruiting | Power Life Sciences Inc. | 500 | 2024-11-01 | 2023-10-26 | |
| The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease. R3R01, Placebo - Diabetic Kidney Disease | Phase 2 | Recruiting | River 3 Renal Corp. | 60 | 2024-10-10 | 2026-09-23 |
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Diabetic Nephropathies (143) · Diabetes Mellitus, Type 2 (38) · Diabetes Mellitus (27) · Renal Insufficiency, Chronic (23) · Diabetes Mellitus, Type 1 (13) · Kidney Diseases (9) · Albuminuria (8) · Diabetes Complications (6) · Obesity (5) · Hypertension (4) · Proteinuria (4) · Cardiovascular Diseases (3) · Pediatric Obesity (3) · Diabetic Retinopathy (2) · Disease (2)
Endocrine System Diseases (143) · Female Urogenital Diseases (143) · Female Urogenital Diseases and Pregnancy Complications (143) · Male Urogenital Diseases (143) · Urogenital Diseases (143) · Urologic Diseases (143) · Diabetes Complications (137) · Kidney Diseases (134) · Diabetes Mellitus (116) · Nutritional and Metabolic Diseases (69) · Glucose Metabolism Disorders (66) · Metabolic Diseases (66) · Pathological Conditions, Signs and Symptoms (44) · Pathologic Processes (27) · Disease Attributes (24)
p-Aminohippuric Acid (7) · Iohexol (6) · empagliflozin (5) · finerenone (5) · dapagliflozin (3) · semaglutide (3) · Angiotensin-Converting Enzyme Inhibitors (2) · Canagliflozin (2) · Cholecalciferol (2) · Dextrans (2) · Irbesartan (2) · Liraglutide (2) · Losartan (2) · Magnetic Resonance Imaging (2) · Pentoxifylline (2)
University of Colorado, Denver (10) · Assiut University (7) · Amsterdam UMC, location VUmc (4) · Renalytix AI, Inc. (4) · Bayer (3) · Chinese PLA General Hospital (3) · Duke University (3) · Gilead Sciences (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · Prokidney (3) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Steno Diabetes Center Copenhagen (3) · Eli Lilly and Company (2) · First Affiliated Hospital of Chongqing Medical University (2) · Medical University of South Carolina (2)
United States (57) · China (24) · Denmark (10) · Canada (9) · Australia (8) · France (7) · Hong Kong (6) · Italy (6) · Netherlands (6) · South Korea (6) · Egypt (5) · Israel (5) · Japan (5) · Mexico (5) · Sweden (5)
Petter Bjornstad, MD (4) · Helen C Looker (2) · Pringgodigdo Nugroho, MD (2) · Aida Lydia, MD, PhD (1) · Alex R Chang, MD, MS (1) · Anna Solini, MD, PhD (1) · Ari Cisneros, Bachelor (1) · Ashraf Anwar Thabet, Professor (1) · Ayub Akbari, MD (1) · Carel le Roux, MBBS PhD (1)
PMID 38682786, PMID 38770818, PMID 39171639, PMID 39963952, PMID 41805697, PMID 14704836, PMID 14768849, PMID 15780110, PMID 16952978, PMID 17035611, PMID 19584489, PMID 20727043, PMID 22245613, PMID 22638939, PMID 22737281, PMID 22777106, PMID 23929927, PMID 24391410, PMID 26180085, PMID 27430216, PMID 27753201, PMID 28449402, PMID 29649631, PMID 30964439, PMID 31018581, PMID 31194487, PMID 31506292, PMID 31659655, PMID 31665733, PMID 31864393, PMID 32600374, PMID 32685766, PMID 33184642, PMID 33280027, PMID 33358451, PMID 33436470, PMID 34400461, PMID 34449181, PMID 34775784, PMID 34879977, PMID 34886001, PMID 35072046, PMID 35333363, PMID 35369650, PMID 35613364, PMID 35679002, PMID 35846333, PMID 36251465, PMID 36287567, PMID 36328655
2014 (2), 2015 (2), 1KL2RR025015-01 (1), 2016 (1), 2017 (1), 2018 (1), K23HL159292 (1), P30DK017047 (1), R21AT002367 (1), R34DK102166 (1), T32DK063687 (1), UL1TR002535 (1)