13 completed, 7 unknown, 4 recruiting, 2 active not recruiting. 23 Not applicable, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 12, Unknown 6, Recruiting 3, Active not recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Depression in Old Age: new trials by email Literature Review of Depression in Old Age trials Research Report on Depression in Old Age
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Leveraging Adult Protective Service Interaction to Offer Evidence-Based Treatment for Depression in Elder Neglect/Self Neglect APS Treatment as Usual, Intervention-Behavioral Activation (BA) - Depression in Old Age | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 50 | 2026-05-15 | 2026-06-30 |
| Research on Three-level Prevention and Intervention for Elderly Depression in Urban Community universal prevention, selective prevention, targeted prevention - Depression in Old Age | Not applicable | Completed | Affiliated Hospital of Yunnan University | 327 | 2024-07-01 | 2025-12-10 |
| Developing a Peer Support Intervention for Depression in SCD PeersCOG - Subjective Cognitive Decline, Depression in Old Age | Not applicable | Active not recruiting | Massachusetts General Hospital | 30 | 2024-05-01 | 2026-07-13 |
| Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures Duloxetine 30 mg - Depression in Old Age, Fragility Fracture | Phase 4 | Recruiting | Wake Forest University Health Sciences | 100 | 2024-04-08 | 2026-03-12 |
| Protocol for a Feasibility Cluster Randomised Controlled Trial of a Home-based Depression Care for Older People Delivered by Lay Providers in Nigeria emhGAP-Age - Depression in Old Age | Not applicable | Unknown | University of Ibadan | 110 | 2024-02-01 | 2023-11-09 |
| RCT of MBCT vs HEP for Late-Life Depression Mindfulness-Based Cognitive Therapy, Health Enhancement Program - Depression in Old Age, Quality of Life | Not applicable | Terminated | Lady Davis Institute | 100 | 2023-10-01 | 2025-06-10 |
| Engage for Late-Life Depression and Comorbid Executive Dysfunction Engage - Depression in Old Age, Psychotherapy | Not applicable | Unknown | University of Nevada, Las Vegas | 20 | 2023-09-24 | 2024-08-06 |
| Efficacy of Metacognitive Training in Older Adults With Depression Metacognitive Training-Silver - Depression in Old Age | Not applicable | Completed | Istanbul University - Cerrahpasa | 50 | 2023-09-15 | 2025-08-26 |
| Improving Adult Protective Services Client Outcomes: A Stepped-Care Social and Mental Health Engagement Program Stepped-care social and mental health engagement, APS Usual care - Depression in Old Age | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 400 | 2023-08-09 | 2026-06-03 |
| Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE) Transcranial Magnetic Stimulation - Aging, Dementia Alzheimers | Enrolling by invitation | Chinese University of Hong Kong | 488 | 2023-06-15 | 2025-01-14 | |
| Study of the Reduction of the Prescriptions of Benzodiazepines and Related Depression in Old Age | Unknown | University Hospital, Strasbourg, France | 150 | 2023-03-01 | 2023-10-30 | |
| Enhancing Processing Speed and Executive Functioning in Depressed Older Adults With Computerized Cognitive Training Experimental: Computerized Cognitive Training, Experimental: Open-label antidepressant treatment, Active Comparator: Solitaire Training - Depression in Old Age, Depression | Phase 1 | Withdrawn | Queens College, The City University of New York | 2023-01-31 | 2023-03-28 | |
| Internet Delivered Psychotherapy for Older Adults Problem-Solving Therapy for Older Adults - Depression in Old Age, Depression, Anxiety | Not applicable | Unknown | University of Calgary | 13 | 2023-01-01 | 2024-04-09 |
| PEERS Plus mHealth Enhanced Peer Support Peers plus - Depression in Old Age | Not applicable | Completed | Massachusetts General Hospital | 34 | 2022-12-15 | 2025-10-08 |
| Assessment of Depression (iCGI) in Older People, According to Their Presentation in a Wheelchair or an Ordinary Chair. Wheelchair - Depression in Old Age | Not applicable | Completed | Hospital Center Guillaume Régnier | 100 | 2021-11-22 | 2024-06-07 |
| Fitness for Brain Optimization for Late-Life Depression On-site AE, At-home AE, Social Engagement (SE) - Depression in Old Age | Not applicable | Completed | University of Pittsburgh | 46 | 2021-08-04 | 2025-11-28 |
| Programme Evaluation on Effectiveness of The Use of Movement-based x 'Elderspirituality - Fu Le Mun Sum' Intervention to Support Elderly People With Depressive Symptoms Dance Movement Therapy (DMT) - Depression in Old Age | Not applicable | Completed | The University of Hong Kong | 135 | 2021-03-01 | 2023-05-09 |
| Creating a Virtual Village for People Aging With HIV During COVID-19 Virtual Village - Hiv, Depression in Old Age | Not applicable | Unknown | University of California, Riverside | 80 | 2021-03-01 | 2021-09-29 |
| High-definition Transcranial Direct Current Stimulation (HD-tDCS) in Late-life Depression (LLD) High-definition Transcranial Direct Current Stimulation - Depression in Old Age | Not applicable | Unknown | The University of Hong Kong | 58 | 2021-02-22 | 2022-04-12 |
| Development of a Healthcare Service Platform for Successful Aging Living-lab digital intervention group - Depression in Old Age, Chronic Pain | Not applicable | Recruiting | Sunmi Song | 84 | 2020-10-21 | 2024-02-21 |
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Depression (11) · Cognitive Dysfunction (4) · Anxiety Disorders (2) · Sleep Initiation and Maintenance Disorders (2) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Chronic Pain (1) · Motor Activity (1) · Parkinson Disease (1) · Pick Disease of the Brain (1) · Psychological Well-Being (1) · Recurrence (1) · Sleep Wake Disorders (1) · Social Isolation (1) · Social Stigma (1)
Behavior (13) · Behavioral Symptoms (11) · Mental Disorders (9) · Neurocognitive Disorders (5) · Cognition Disorders (4) · Nervous System Diseases (3) · Dyssomnias (2) · Pathological Conditions, Signs and Symptoms (2) · Sleep Disorders, Intrinsic (2) · Social Behavior (2) · Basal Ganglia Diseases (1) · Blood-Borne Infections (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Communicable Diseases (1)
Aging (1) · Cognitive Behavioral Therapy (1) · Duloxetine Hydrochloride (1) · Endotoxins (1) · Exercise (1) · Ketamine (1) · Mindfulness-Based Cognitive Therapy (1) · Transcranial Magnetic Stimulation (1) · Wheelchairs (1) · engage 8200 (1)
Massachusetts General Hospital (2) · The University of Hong Kong (2) · The University of Texas Health Science Center, Houston (2) · Weill Medical College of Cornell University (2) · Affiliated Hospital of Yunnan University (1) · Chiayi Christian Hospital (1) · Chinese University of Hong Kong (1) · Hospital Center Guillaume Régnier (1) · Instituto Mexicano del Seguro Social (1) · Istanbul University - Cerrahpasa (1) · Lady Davis Institute (1) · Michael Irwin, MD (1) · Queens College, The City University of New York (1) · Sunmi Song (1) · University Hospital, Strasbourg, France (1)
United States (15) · Hong Kong (3) · Canada (2) · France (2) · China (1) · Mexico (1) · Norway (1) · South Korea (1) · Taiwan (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Adam JZ Kadri (1) · Amruta Barve, MPH (1) · Brenna Renn, PhD (1) · Bruce E Wexler (1) · Hanna LU, PhD (1) · Jason Burnett, PhD (1) · Jo Anne Sirey, Ph.D. (1) · Joel R Sneed, PhD (1) · Julia Kirkham, MD (1) · Junesun Kim, PhD (1) · Lara Guedes de Pinho, Assoc Prof, PhD, RN (1)
PMID 20434997, PMID 21665534, PMID 21840287, PMID 22104190, PMID 23615118, PMID 25179996, PMID 26329381, PMID 27056623, PMID 27965533, PMID 29111077, PMID 29169814, PMID 31695391, PMID 36118690, PMID 36307858, PMID 37256193, PMID 38885033, PMID 40668551, PMID 41023858, PMID 41298372, PMID 42061838
P50MH113838 (2), K23MH125074 (1), P30AG086563 (1), P50MH115837 (1), R01MH121384 (1), R33MH126187 (1)