Developing a Peer Support Intervention for Depression in SCD

NCT06358404 — Not applicable, Active not recruiting, 30 participants, Massachusetts General Hospital

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Registry	NCT06358404
Status	Active not recruiting
Phase	Not applicable
Study type	Interventional; na, single group, masking: none, health services research
Enrollment	30 (Estimated)
Sponsor	Massachusetts General Hospital (Other); collaborators: National Institutes of Health (NIH)
Conditions	Subjective Cognitive Decline, Depression in Old Age
Interventions	PeersCOG (Behavioral)
Dates	start 2024-05-01, primary completion 2027-05-31 (estimated), completion 2027-05-31 (estimated), first posted 2024-04-10, last updated 2026-07-13
Locations	1 site in United States

-Summary

The purpose of this study is to assess the feasibility, acceptability, and fidelity of an 8-week intervention where peer coaches will deliver depression care to adults 60 years of age or older who have depression and subjective cognitive decline.

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+Detailed description

With support from the MADRC ORE Core, we will recruit 30 community-dwelling older adults to conduct an open pilot study of PeersCOG. Trained and supervised peer coaches will deliver depression care to adults 60 years of age and older with depression and subjective cognitive decline in an 8-week intervention using video chats and texts. We will use mixed methods to assess feasibility, acceptability, and fidelity. We will use validated instruments to assess the preliminary outcomes, including depression, SCD, functioning, and social factors at baseline, 8 weeks, and 3 months, and we will conduct post-intervention interviews with stakeholders at 8 weeks. Older adult participants will be asked to name a study partner who will support the older adult throughout the study in terms of study enrollment. They may also have additional perspectives on the impact of impaired cognition and depression on daily living and related needs. The older adult will not be excluded if the study partner is not available.

+Arms and interventions

Arm	Type	Interventions	Description
Intervention	Other	Behavioral: PeersCOG	Peer coaches will deliver the PeersCOG intervention to participants.

PeersCOG (Behavioral): . The intervention will consist of 8 weekly video chats focused on emotional, appraisal, and informational support delivered by community-based older adult peer coaches to adults 60 years of age and older with subthreshold depression and SCD.

+Outcome measures

Primary outcomes

Feasibility of Intervention [Measured at baseline enrollment]: Level of participant engagement: how many screened older adults agree to participate in the intervention and complete baseline assessments
Acceptability of Intervention [Measured during intervention (8 weeks)]: Number of meetings older adults complete with peer coach
Fidelity of Intervention [Measured during intervention (8 weeks)]: Degree of adherence to intervention

+Eligibility

Sex: All, ages: 60 Years to any

Inclusion Criteria:

* Older adults aged 60+
* Endorse subjective cognitive decline
* Endorse depressive symptoms
* not currently experiencing suicidal ideation nor active, untreated manic, psychotic, or substance use disorder
* fluent in English and able to give informed consent

Exclusion Criteria:

* Meets diagnostic criteria for mild cognitive impairment or Alzheimer's dementia
* Meets diagnostic criteria for a current major depressive disorder
* have a history of neurological and psychiatric comorbidities such as major depressive disorder in the past 12 months

+Locations (1)

Facility	City	Country	Status
Massachusetts General Hospital	Boston, Massachusetts	United States