127 completed, 32 unknown, 27 recruiting, 20 not yet recruiting. 195 Not applicable, 2 Phase 4, 1 Early Phase 1, 1 Phase 2.
Follow Social Isolation: new trials by email Literature Review of Social Isolation trials Research Report on Social Isolation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Experiment Among Smokers in Which Two Variables Are Manipulated: Ostracism and Concealability Do men and women differ in their reactions to the experimental conditions. - Ostracism | Not applicable | Not yet recruiting | Dickinson College | 340 | 2028-05-01 | 2024-06-17 |
| Testing a Peer-Support Group for Veterans Who Hear Voices Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP) - Psychotic Disorders, Hallucinations, Auditory | Not applicable | Not yet recruiting | VA Office of Research and Development | 160 | 2027-04-01 | 2026-04-29 |
| Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study Social Judgment Paradigm - Schizotypy | Not applicable | Not yet recruiting | Central Connecticut State University | 100 | 2027-01-01 | 2026-09-21 |
| A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement Social Reminder System - Memory Disorders, Mild Cognitive Impairment | Not applicable | Not yet recruiting | University of Minnesota | 200 | 2026-11-01 | 2026-08-19 |
| Does Attachment Anxiety Moderate the Influence of Social Rejection on Alcohol Use Among Young Adults? Social Rejection Feedback, Social Acceptance - Social Rejection, Attachement Style | Not applicable | Recruiting | University of North Carolina, Wilmington | 152 | 2026-10-05 | 2026-10-29 |
| The BASIC-S Feasibility Study for Vascular Risk Reduction BASIC-S Intervention, Standard / Usual Care - Hypertension (HTN), Vascular Diseases | Not applicable | Not yet recruiting | Andrew Appleton | 120 | 2026-10-01 | 2026-08-25 |
| The Women Veteran's Health Mission Online Web-based Health Promotion - Chronic Pain, Poor Sleep Quality | Not applicable | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 500 | 2026-10-01 | 2026-05-27 |
| The Impact of Long-term Isolation in Antarctica on Social Touch and Its Underlying Biological Mechanisms in Winter-over Crew Members, Assessed During Their Stay Using Standardized Touch Stimulation, Computer-based Touch Sensitivity Tests, Questionnaires and Biological Markers. No Intervention: Observational Cohort - Social Isolation, Isolated Confined and Extreme Conditions | Not yet recruiting | Vrije Universiteit Brussel | 28 | 2026-10-01 | 2026-10-05 | |
| AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults AI-based conversational intervention - Mild Cognitive Impairment (MCI), Social Isolation | Not applicable | Not yet recruiting | Massachusetts General Hospital | 80 | 2026-10-01 | 2026-08-25 |
| Refugee Mental Health and Wellness Pilot Study Wellbeing Program - Social Isolation | Not applicable | Withdrawn | University of California, Los Angeles | 2026-10-01 | 2026-10-21 | |
| Effectiveness of a Psychological Intervention to Reduce Social Isolation and Promote Social Connectedness in Young Adults Digital-Assisted Group Social Skills Training - Social Isolation, Loneliness | Not applicable | Not yet recruiting | Korea University | 80 | 2026-09-30 | 2026-09-24 |
| Social Connection Collective for Older Adults in Subsidized Housing Social Connection Collective: Open-Label Pilot, Social Connection Collective: Pilot - Social Isolation in Older Adults, Social Isolation or Loneliness | Not applicable | Recruiting | Johns Hopkins University | 300 | 2026-09-23 | 2026-10-07 |
| A Mechanism Randomised Controlled Trial of a Three-Agent LLM-Augmented mHealth Intervention for Late-Life Loneliness in Older Adults Hybrid conversational companion application, Rule-based conversational companion application - Loneliness, Social Isolation | Not applicable | Not yet recruiting | The University of Hong Kong | 72 | 2026-09-21 | 2026-09-16 |
| Improving Diet Quality of Community-Dwelling Seniors Using a Community-Based Participatory Approach Food Literacy Workshops - Diet Quality, Social Isolation in Older Adults | Not applicable | Not yet recruiting | Geriatric Education and Research Institute | 50 | 2026-09-01 | 2026-10-07 |
| Evaluation of Choose to Move Replacement Ready (CTM-RR) Choose to Move Replacement Ready - Osteoarthritis (OA), Osteoarthritis (OA) of the Hip | Not applicable | Recruiting | University of British Columbia | 210 | 2026-09-01 | 2026-08-24 |
| Talk2gether Program for Social Connection in Older Adults Talk2gether program - Social Isolation or Loneliness | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 50 | 2026-08-03 | 2026-08-24 |
| Social Prescribing for a Mindful Lifestyle Mindfulness Lifestyle Social Prescribing Program - Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness | Not applicable | Recruiting | Buddhist Tzu Chi General Hospital | 50 | 2026-07-09 | 2026-10-02 |
| The Effect of Comorbid Alcohol/Substance Use case (comorbid diagnosis), control - Alcohol Abuse, Alcohol Use Disorder | Recruiting | Abant Izzet Baysal University | 297 | 2026-06-20 | 2026-07-13 | |
| Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness. - Social Isolation in Older Adults, Loneliness | Not applicable | Active not recruiting | Universidad de Especialidades Espiritu Santo | 500 | 2026-06-01 | 2026-07-09 |
| AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS) Asynchronous coaching and artificial intelligence (AI) Yoodli coach sessions - Communication, Anxiety | Not applicable | Active not recruiting | Milton S. Hershey Medical Center | 10 | 2026-04-14 | 2026-09-01 |
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