65 completed, 15 unknown, 13 recruiting, 5 active not recruiting. 50 Not applicable, 6 Phase 2, 6 Phase 4, 5 Phase 1, 4 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of a New Virtual Care Pathway for Older Adults With Noncommunicable Diseases Teleconsultation care pathway for older adults with NCDs (TeleCOOP-NCD©) - Hypertension (HTN), Diabetes | Not applicable | Recruiting | National University of Malaysia | 160 | 2026-09-02 | 2026-10-16 |
| Cross-Education From Unilateral Strength and Balance Training in Older Adults With Bilateral Knee Osteoarthritis 8-Week Unilateral Strength and Balance Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Balance Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Strength Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis - Knee Osteoarthritis (OA) | Not applicable | Not yet recruiting | University of Zagreb | 45 | 2026-09-01 | 2026-03-24 |
| Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease, Attention Control for Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease - Lower Extremity Muscle Strength | Not applicable | Enrolling by invitation | VA Office of Research and Development | 30 | 2026-07-15 | 2026-07-31 |
| Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional Study Systemically healthy individuals 18-45 years of age, having gingival recession - Gingival Recession | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 346 | 2026-03-15 | 2026-04-29 | |
| Exercise and Gezaixi Interventions on Community-Dwelling Older Adults Strength Training plus Taiwanese Opera-based Activities - Frailty, Functional Decline | Not applicable | Completed | National Taipei University of Nursing and Health Sciences | 120 | 2025-12-20 | 2026-04-17 |
| Multicenter Randomized Controlled Trial (RCT) and Efficacy Evaluation System Study on Surgical Innovation Strategies for Neonatal Complex Congenital Heart Disease Surgical operation is performed on neonates aged >7 days (postnatal age), Surgical operation is performed on neonates aged < 7 days (postnatal age). - Complex Congenital Heart Disease | Not applicable | Recruiting | Central China Fuwai Hospital of Zhengzhou University | 738 | 2025-12-01 | 2026-01-23 |
| Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults FEXO (Fun Exercise for Older Adults) - Frailty Syndrome, Sarcopenia | Not applicable | Completed | Cardenal Herrera University | 80 | 2025-09-04 | 2026-04-21 |
| Fun Exercise Intervention for Older Adults to Improve Intrinsic Capacity and Motivation Fun Exercise for Older Adults (FEXO), OTAGO - Sarcopenia, Frailty Syndrome | Not applicable | Completed | Cardenal Herrera University | 120 | 2025-09-04 | 2026-04-08 |
| The Effect of Swallowing Exercise and Maneuver Program For Older Adults With Dysphagia in Nursing Home Swallowing Exercise and Maneuver Program for Older Adults with Dysphagia - Oropharyngeal Dysphagia, Swallowing Disorders | Not applicable | Not yet recruiting | Universitas Indonesia | 72 | 2025-07-10 | 2025-07-03 |
| A Randomized Control Trial of Enhanced Cognitive Behavioural Group Therapy for Older Adults with Depression: Efficacy Across Older Age-Groups Cognitive Behavior Therapy for Older Adults (CBT-OA) - Major Depression | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-07-01 | 2025-03-25 |
| COBRA: Cancer, Older Adults, Balance and Resistance Activities Cancer, Older adults, Balance and Resistance Activities - Primary Cancer, Metastatic Cancer | Not applicable | Active not recruiting | Memorial Sloan Kettering Cancer Center | 38 | 2025-05-30 | 2026-04-24 |
| The Effect of Body Mass Index on Taste Perception,Salivary Hormones and Oral Health Status body mass index for age - Oral Health, Tast Perference | Not yet recruiting | Al-Mustansiriyah University | 90 | 2025-04-30 | 2025-04-29 | |
| Age-dependent EEG Characteristics During Desflurane Anesthesia From Adults to Elderlies Age - EEG, Aging | Completed | Chinese PLA General Hospital | 47 | 2025-04-24 | 2025-11-21 | |
| Investigation of Tetralogy of Fallot in Neonates corrective surgery within 28 days of birth, corrective surgery between 3-6 months of age - Tetralogy of Fallot (TOF), Pulmonary Stenosis | Not applicable | Recruiting | Beijing Anzhen Hospital | 160 | 2025-03-01 | 2026-10-13 |
| Understanding the Preferences and Views of Older Adults on the Use of Geriatric and Objective Functional Assessments for Cancer Treatment Planning. Cancer care delivery - Care Delivery, Geriatrics | Not applicable | Recruiting | Fox Chase Cancer Center | 100 | 2025-02-21 | 2026-09-21 |
| The engAGE Project: Immersive Intergenerational Intervention to Improve Movement in Older Adults immersive technology-based intergenerational intervention to improve movement patterns in older adults - Frailty at Older Adults | Not applicable | Active not recruiting | University Ramon Llull | 240 | 2025-02-03 | 2025-12-05 |
| Reforça't: A Community, Social, and Healthcare Program for Patients With Cardiorespiratory Conditions Upon Hospital Discharge Interdisciplinary Program for Post-Hospitalization / Hospital at home Management and Long-Term Outcomes in Older Adults with Chronic Cardiorespiratory Condition - Chronic Obstructive Lung Disease (COLD), Heart Failure | Not applicable | Recruiting | Corporació de Salut del Maresme i la Selva | 200 | 2025-01-13 | 2025-05-30 |
| A Study Comparing the Differences Between Young and Non-young Breast Cancer Age, combination therapy - Breast Cancer | Enrolling by invitation | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 3000 | 2025-01-01 | 2025-02-14 | |
| Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE) PK-optimized oral hydroxyurea at MTD until 15 years of age. - Sickle Cell Anemia (HbSS), Sickle-β0-thalassemia (HbSβ0) | Phase 4 | Recruiting | Children's Hospital Medical Center, Cincinnati | 50 | 2024-12-19 | 2025-09-16 |
| Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing D-THIO (Deprescribing Thyroid Hormone In Older Adults), Enhanced usual care - Hypothyroidism | Not applicable | Recruiting | University of Michigan | 900 | 2024-12-02 | 2026-09-04 |
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Frailty (6) · Poliomyelitis (5) · Depression (4) · Neoplasms (4) · COVID-19 (3) · Cognitive Dysfunction (3) · Sarcopenia (3) · Breast Neoplasms (2) · Diabetes Mellitus (2) · Hypertension (2) · Influenza, Human (2) · Lung Neoplasms (2) · Motor Activity (2) · Sedentary Behavior (2) · 2-Methylbutyryl-CoA Dehydrogenase Deficiency (1)
Centers for Disease Control and Prevention (4) · Memorial Sloan Kettering Cancer Center (4) · Assistance Publique - Hôpitaux de Paris (2) · Cardenal Herrera University (2) · Chang Gung Memorial Hospital (2) · Duke University (2) · First Affiliated Hospital Xi'an Jiaotong University (2) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (2) · National Taipei University of Nursing and Health Sciences (2) · University of Illinois at Chicago (2) · VA Office of Research and Development (2) · Al-Mustansiriyah University (1) · American Board of Internal Medicine (1) · Andros Day Surgery Clinic (1) · Arcturus Therapeutics, Inc. (1)
United States (24) · China (14) · Spain (10) · France (7) · Bangladesh (5) · Taiwan (5) · United Kingdom (5) · Brazil (3) · South Korea (3) · Turkey (Türkiye) (3) · Canada (2) · India (2) · Italy (2) · Norway (2) · Australia (1)
Chu-Ling Yen (2) · Katherine Ramos, Ph.D. (2) · Adamantia Nikolaidi, MD (1) · Allison Kempe, MD, MPH (1) · Andy Pringle, PhD (1) · Atsushi Kamijo (1) · Ayan Dey, Ph.D (1) · Aznida Firzah Abdul Aziz, MBBS, MMed, PhD (1) · Bar-David Yair, MD (1) · Beth Kirkpatrick, M.D. (1) · Bo Wang, MD PhD (1) · Charles T. Quinn, Professor of Pediatrics, M.D., M.S. (1)
PMID 16772388, PMID 2229948, PMID 22731653, PMID 24103232, PMID 28194449, PMID 28339500, PMID 28395844, PMID 29119726, PMID 29571817, PMID 30191144, PMID 31104832, PMID 33118951, PMID 33970109, PMID 35111880, PMID 35961362, PMID 36030342, PMID 36317512, PMID 36447027, PMID 36510778, PMID 36931672, PMID 36987384, PMID 37386363, PMID 37574601, PMID 38283151, PMID 39026197, PMID 40179934, PMID 40334011, PMID 40940906, PMID 40977696, PMID 41432992, PMID 42203285, PMID 42818472
P30AG022849 (2), 1IK2CX002595-01A2 (1), 2009 (1), I21RX003898 (1), K01MH115794 (1), R01AG074959 (1), R01AG079833 (1), R01CA240649 (1), R01DK127916 (1), R01HD061265 (1), R15AG055906 (1)