47 completed, 12 unknown, 6 not yet recruiting, 5 recruiting. 42 Not applicable, 13 Phase 3, 9 Phase 2, 9 Phase 4, 2 Phase 1.
Follow Dentin Hypersensitivity: new trials by email Literature Review of Dentin Hypersensitivity trials Research Report on Dentin Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study D Blue Diode Laser, ProSylc Bioactive Glass Powder - Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity | Not applicable | Not yet recruiting | Cukurova University | 30 | 2026-07-20 | 2026-06-15 |
| Effectiveness of Two Different Desensitizing Dental Varnishes Fluoride-containing varnish, Fluoride-free varnish - Dentin Hypersensitivity, Dentin Desensitizing Agents | Not applicable | Recruiting | Ivoclar Vivadent AG | 66 | 2026-07-13 | 2026-08-20 |
| Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity Diode laser photobiomodulation combined with CPP-ACPF varnish, CPP-ACPF varnish - Dentin Hypersensitivity, Tooth Hypersensitivity | Not applicable | Not yet recruiting | Cairo University | 70 | 2026-04-01 | 2026-03-04 |
| Efficacy of Dissolvable Mineral Loaded Starch Particles Strips in Providing Rapid Relief of Dentin Hypersensitivity: A Randomized Clinical Trial dissolvable mineral-loaded starch particle strips, Novamin containing toothpaste - Dentin Hypersensitivity | Phase 4 | Completed | Cairo University | 82 | 2026-03-10 | 2026-06-25 |
| Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated. epidemiological - Dentin Hypersensitivity, Erosive Tooth Wear | Recruiting | Indiana University | 2500 | 2026-02-19 | 2026-05-05 | |
| A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers Dentin Hypersensitivity | Recruiting | HALEON | 375 | 2025-12-16 | 2026-04-28 | |
| A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste - Dentin Hypersensitivity | Not applicable | Completed | HALEON | 254 | 2025-12-15 | 2026-03-31 |
| Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control) - Post-operative Sensitivity, Dentin Hypersensitivity | Phase 2 / Phase 3 | Not yet recruiting | Beenish Hassan | 60 | 2025-12-01 | 2025-09-23 |
| Laser Therapy for Dentin Hypersensitivity Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany) - Dentin Hypersensitivity | Not applicable | Completed | Hacettepe University | 25 | 2025-11-11 | 2026-10-21 |
| Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice - Dentin Hypersensitivity | Phase 3 | Completed | HALEON | 688 | 2025-09-16 | 2026-08-25 |
| Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial) episodic use of the desensitizing toothpaste, continuous use of the conventional desensitizing toothpaste - Dentin Hypersensitivity | Not applicable | Not yet recruiting | Rawda Hesham Abd ElAziz | 50 | 2025-08-20 | 2025-08-13 |
| Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac Patients Biorepair Toothpaste and Mousse, Biorepair® Toothpaste - Celiac Disease, Dentin Hypersensitivity | Not applicable | Recruiting | University of Pavia | 40 | 2025-07-30 | 2026-04-23 |
| Combined Use of Potassium Nitrate Gel and Diode Laser for Dentin Hypersensitivity Potassium Nitrate Gel, Diode Laser (Active), Diode Laser (Sham) - Dentin Hypersensitivity | Not applicable | Completed | University of Pavia | 23 | 2025-07-15 | 2026-01-13 |
| Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste test toothpaste, Control toothpaste - Dentin Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-05-10 | 2026-03-19 |
| Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study laser treatment, application of desensitizing agent, Placebo - Dentin Hypersensitivity | Not applicable | Not yet recruiting | Ege University | 40 | 2025-05-01 | 2025-03-03 |
| Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity toothpaste - Dentin Hypersensitivity | Not applicable | Not yet recruiting | Minia University | 60 | 2025-05-01 | 2025-05-11 |
| Management of Dentin Hypersensitivity in Patients With Periodontitis Gluma Desensitizer and ER:CR;YSGG laser combination, Er,Cr:YSGG laser - Dentin Hypersensitivity | Not applicable | Completed | Trakya University | 48 | 2025-04-10 | 2025-12-16 |
| Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer - Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity | Phase 2 / Phase 3 | Active not recruiting | British University In Egypt | 84 | 2025-04-01 | 2025-08-13 |
| Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity Mouthwash preparation - Dentin Hypersensitivity | Phase 3 | Recruiting | Dr. D. Y. Patil Dental College & Hospital | 40 | 2025-02-25 | 2025-02-13 |
| Effect of Chemical and Light Bleaching Techniques on Color Change, Dentin Hypersensitivity and Patient Satisfaction Light activated bleaching, Chemically activated bleaching - Dentin Hypersensitivity | Not applicable | Completed | Nahda University | 30 | 2025-02-15 | 2026-06-25 |
Showing 20 of 72. Sign in to see all of them.
Dentin Sensitivity (72) · Celiac Disease (1) · Chronic Periodontitis (1) · Dental Caries (1) · Dental Pulp Exposure (1) · Gingival Recession (1) · Gingivitis (1) · Hypersensitivity (1) · Pain, Postoperative (1) · Periodontal Diseases (1) · Tooth Abrasion (1) · Tooth Demineralization (1) · Tooth Discoloration (1) · Tooth Erosion (1) · Toothache (1)
Stomatognathic Diseases (72) · Tooth Diseases (72) · Mouth Diseases (4) · Pathological Conditions, Signs and Symptoms (3) · Periodontal Diseases (3) · Gingival Diseases (2) · Neurologic Manifestations (2) · Pain (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Tooth Demineralization (2) · Tooth Wear (2) · Chronic Disease (1) · Dental Pulp Diseases (1) · Digestive System Diseases (1)
Low-Level Light Therapy (5) · gluma desensitizer (5) · Fluorides (3) · Lasers, Semiconductor (3) · Sodium Fluoride (3) · Bifluorid 12 (2) · Gluma (2) · Tin Fluorides (2) · Toothpastes (2) · sodium fluoride topical preparation (2) · Acidulated Phosphate Fluoride (1) · Arginine (1) · Clinpro Sealant (1) · Control Groups (1) · Cyanoacrylates (1)
Cairo University (8) · University of Sao Paulo (4) · Colgate Palmolive (3) · Dow University of Health Sciences (3) · Federal University of Uberlandia (3) · HALEON (3) · Al-Azhar University (2) · British University In Egypt (2) · HysensBio Co., Ltd (2) · I.M. Sechenov First Moscow State Medical University (2) · University of Pavia (2) · Alexandria University (1) · Baskent University (1) · Beenish Hassan (1) · Cukurova University (1)
Egypt (16) · Brazil (9) · United States (8) · Turkey (Türkiye) (5) · Pakistan (4) · China (3) · Saudi Arabia (3) · Italy (2) · Russia (2) · Canada (1) · France (1) · Germany (1) · India (1) · Jordan (1) · Liechtenstein (1)
Andrea Scribante, Associate Professor (2) · Adriana Romo, DDS (1) · Ahmed A Holiel, Lecturer (1) · Ahmed M Sayed, Assis. prof. (1) · Arlin Kiremitci (1) · Augusto Elias, DDS (1) · Ayse Ruya Yazici, Prof. (1) · Camila Tirapeli, PhD (1) · Camila Tirapelli, PhD (1) · Cecy M Silva (1) · Dalia N AlHarith (1)
PMID 31150729, PMID 31415787, PMID 31640741, PMID 34615511, PMID 34676918, PMID 38745306, PMID 38783427, PMID 38821658, PMID 40444818, PMID 41612333, PMID 41696662, PMID 41831557