12 completed, 2 unknown, 1 active not recruiting. 5 Not applicable, 5 Phase 4, 4 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Active not recruiting 1, Unknown 1 |
| Phase 4 | 5 | Completed 5 |
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow sodium fluoride topical preparation: new trials by email Literature Review of sodium fluoride topical preparation trials Research Report on sodium fluoride topical preparation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Root Caries Prevention Using Fluoride Varnish Fortified With SBGC Fluoride varnish with SBGC, Fluoride varnish - Dental Caries of Root Surface, Root Caries | Not applicable | Active not recruiting | The University of Hong Kong | 540 | 2024-01-15 | 2026-04-29 |
| SDF With or Without Fluoride Varnish for Caries Arrest in Primary Teeth of Young Children Silver Diamine Fluoride (SDF, 38%) and Sodium Fluoride Varnish (NaF, 5%), Silver Diamine Fluoride (SDF, 38%) - Dental Caries | Not applicable | Completed | Beaty Dent | 104 | 2021-01-07 | 2025-09-03 |
| Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®) - Dentin Hypersensitivity, Active Dental Caries | Phase 2 / Phase 3 | Completed | University Medicine Greifswald | 30 | 2020-01-13 | 2021-05-06 |
| Effect of Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride Varnish on Remineralization of White Spot Lesion in Primary Teeth CPP-ACP, Duraphat - White Spot Lesion | Phase 2 | Completed | Nourhan M.Aly | 180 | 2019-04-28 | 2020-04-22 |
| Glass Ionomer Sealant Versus Fluoride Varnish on Occlusal Caries Prevention 5% sodium fluoride varnish (NaF), Glass ionomer sealant (GIS) - Pit and Fissure Caries, Glass Ionomer Cements | Not applicable | Unknown | The University of Hong Kong | 348 | 2018-04-11 | 2019-11-14 |
| Effect of Curodont Repair on Color Change of White Spot Lesions Curodont Repair, fluoride varnish - White Spot Lesion | Phase 2 | Unknown | Cairo University | 64 | 2017-01-01 | 2016-09-26 |
| Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity 5% Sodium Fluoride Varnish, 15% Nanohydroxyapetite paste, Glycerol - Dentin Hypersensitivity | Phase 4 | Completed | Riyadh Colleges of Dentistry and Pharmacy | 63 | 2016-10-01 | 2020-03-11 |
| Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children fluoride varnish 22600ppm - Dental Caries | Phase 1 / Phase 2 | Completed | University of Peradeniya | 320 | 2016-08-01 | 2018-12-12 |
| Cost-effectiveness of Topical Fluoride in Preventing Deciduous Dental Caries in Preschool Children 1.23% fluoride foam application, 2.26% fluoride varnish application - Dental Caries in Children | Not applicable | Completed | National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC | 1083 | 2016-07-01 | 2021-11-12 |
| Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars Fluoride Varnish, Control Group - Dental Caries | Phase 4 | Completed | Universidad Iberoamericana | 180 | 2015-03-01 | 2016-11-04 |
| In Situ Remineralisation Response of Different Artificial Caries-like Enamel Lesions to Home-care and Professional Fluoride Treatments Application of fluoride varnish (22600 ppm F, Duraphat) at the begining of the study, Application of fluoride toothpaste (1500 ppm F, Crest) twice a day for 3 days of the study, Application of placebo toothpaste (0 ppm F, Ice Fresh) twice a day for 3 days of the study - Dental Caries | Not applicable | Completed | University of Sao Paulo | 12 | 2012-01-01 | 2015-12-24 |
| Impact of Fluoride Vanish Application in Dental Prevention for Elderly Duraphat - Tooth Decay | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 179 | 2009-10-01 | 2016-05-10 |
| The Behaviour of Dental Nurses Applying Fluoride Varnish to Young Children Fluoride varnish - Dental Caries | Completed | University of St Andrews | 509 | 2009-04-01 | 2013-01-10 | |
| Impact of Maternal Xylitol Consumption on Mutans Sterptococci xylitol, fluoride varnish application - Dental Caries and Streptococcus Mutans Count | Phase 4 | Completed | King Abdulaziz University | 60 | 2009-02-01 | 2014-01-14 |
| Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study sodium fluoride, sodium fluoride calcium fluoride - Dental Caries | Phase 4 | Completed | University of Pernambuco | 45 | 2007-02-01 | 2008-07-28 |
Dental Caries (9) · Dentin Sensitivity (2) · Plaque, Amyloid (1) · Root Caries (1) · Van der Woude syndrome (1)
The University of Hong Kong (2) · Assistance Publique - Hôpitaux de Paris (1) · Beaty Dent (1) · Cairo University (1) · King Abdulaziz University (1) · National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC (1) · Nourhan M.Aly (1) · Riyadh Colleges of Dentistry and Pharmacy (1) · Universidad Iberoamericana (1) · University Medicine Greifswald (1) · University of Peradeniya (1) · University of Pernambuco (1) · University of Sao Paulo (1) · University of St Andrews (1)
Hong Kong (2) · Saudi Arabia (2) · Albania (1) · Brazil (1) · Egypt (1) · France (1) · Germany (1) · United Kingdom (1)
Adriana DB Rosa, student (1) · Ahmed I Mekky, BDS (1) · Chunxiao Wang (1) · Cynthia Kar Yung Yiu, FHKAM,FCDSHK (1) · Dalia AM Talaat, PhD (1) · Dalia N AlHarith (1) · Fabio C Sampaio, PhD (1) · Gerald M Humphris, PhD (1) · Jainara MS Ferreira, Master (1) · Karin ML Dowidar, PhD (1) · Katherine CM Leung, BDS,MDS,PhD (1) · Manola Kelmendi, DMD, PhD (1) · Marysette Folliguet (1) · Mohamed H Abudrya, BDS, MSc. (1)
PMID 15942186, PMID 16903196, PMID 20027453, PMID 20606432, PMID 23534323, PMID 24311016, PMID 27100884, PMID 30373592, PMID 34284374