15 completed, 4 recruiting, 4 unknown, 2 terminated. 17 Not applicable, 4 Phase 4, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 10, Recruiting 3, Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 4 | Completed 4 |
| Phase 2 | 2 | Enrolling by invitation 1, Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Delusional Disorder: new trials by email Literature Review of Delusional Disorder trials Research Report on Delusional Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shared Decision Making for Antipsychotic Medications The Antipsychotic Medication Decision Aid (APM-DA) - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | New York State Psychiatric Institute | 120 | 2027-01-01 | 2026-03-30 |
| Enhancing Veteran-Clinical Collaboration in VA PRRCs Collaborative Decision Skills Training, Leveling Up - Schizophrenia, Schizoaffective Disorder | Not applicable | Recruiting | VA Office of Research and Development | 119 | 2026-08-12 | 2026-08-19 |
| FEEL-GOOD: A Multicenter Trial of a Mindfulness-Based Group Therapy in Young Adults With Early Psychosis FEEL GOOD, Treatment as Usual (TAU) - Delusional Disorder, Brief Psychotic Disorder | Not applicable | Recruiting | Stephanie Mehl | 252 | 2026-05-27 | 2026-09-22 |
| SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities SUCCEED Community-Based Intervention - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 425 | 2025-09-18 | 2026-06-08 |
| Young Adults With Violent Behavior During Early Psychosis (Aim 2) adapted behavioral intervention - Schizophrenia, Schizo Affective Disorder | Not applicable | Completed | Columbia University | 12 | 2024-03-19 | 2026-10-05 |
| The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric Care Metacognitive Skills Training (MCT), Treatment as usual - Schizophrenia, Schizoaffective Disorder | Not applicable | Recruiting | University of Jyvaskyla | 85 | 2023-09-01 | 2024-05-14 |
| Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services Schizophrenia Spectrum and Other Psychotic Disorders, Schizophrenia | Recruiting | Beth Israel Deaconess Medical Center | 320 | 2023-01-01 | 2026-03-10 | |
| Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders Cognitive Remediation (REHACOP), Metacognitive Training (MCT) - Schizophrenia, Schizophreniform Disorders | Not applicable | Unknown | Universitat Autonoma de Barcelona | 160 | 2022-09-01 | 2024-05-23 |
| Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness Collaborative Decision Skills Training, Leveling Up - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | VA Office of Research and Development | 39 | 2022-07-05 | 2025-12-26 |
| Rituximab Treatment for Psychosis And/or Obsessive Compulsive Disorder with Probable Immune System Involvement Rituximab - Obsessive-Compulsive Disorder, Obsessive-Compulsive Behavior | Phase 2 | Enrolling by invitation | Uppsala University Hospital | 40 | 2022-05-01 | 2024-11-19 |
| Feasibility of a Novel Process-based Treatment for Patients With Psychosis Metacognitive and Defusion Training - Schizophrenia, Schizotypal Disorder | Not applicable | Completed | Max-Planck-Institute of Psychiatry | 37 | 2021-05-10 | 2023-10-23 |
| The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis OPUS YOUNG, Treatment as Usual - Schizophrenia, Schizotypal Disorder | Not applicable | Completed | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 284 | 2021-05-06 | 2026-08-20 |
| Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic Disorders Individual cognitive stimulation therapy (iCST) - Psychotic Disorders, Schizophrenia | Not applicable | Completed | CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas | 38 | 2021-03-29 | 2022-03-10 |
| Research Into Antipsychotic Discontinuation and Reduction Trial Antipsychotic Reduction, Antipsychotic Maintenance - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | University College, London | 253 | 2016-03-24 | 2022-05-23 |
| D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions D-Cycloserine, Placebo, Cognitive Behavioral Therapy - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | NYU Langone Health | 58 | 2014-02-01 | 2020-03-25 |
| Pilot-trial of Emotion-focused Cognitive Behavior Therapy for Patients With Schizophrenia CBT-E, Treatment as Usual - Schizophrenia, Delusional Disorder | Not applicable | Completed | Philipps University Marburg | 64 | 2014-01-01 | 2020-03-04 |
| Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH) agomelatine - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | Central Institute of Mental Health, Mannheim | 27 | 2013-01-01 | 2018-03-08 |
| Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis Multi-element, team-oriented treatment - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | Research Foundation for Mental Hygiene, Inc. | 65 | 2010-10-01 | 2016-11-03 |
| Minimizing Doses of Antipsychotic Medication in Older Patients With Schizophrenia. Risperidone/Olanzapine and PET scans - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | Centre for Addiction and Mental Health | 45 | 2009-10-01 | 2022-06-06 |
| Acceptance and Commitment Therapy for Delusions Acceptance and Commitment Therapy - Schizophrenia, Delusional Disorder | Not applicable | Completed | Weill Medical College of Cornell University | 4 | 2008-04-01 | 2009-10-12 |
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Schizophrenia (27) · Schizophrenia, Paranoid (27) · Psychotic Disorders (25) · Bipolar Disorder (4) · Mental Disorders (4) · Depressive Disorder, Major (3) · Schizotypal Personality Disorder (3) · Delusions (2) · Emotional Regulation (2) · Mania (2) · Schizophrenia Spectrum and Other Psychotic Disorders (2) · Aggression (1) · Compulsive Behavior (1) · Depression (1) · Diabetes Mellitus, Type 2 (1)
Schizophrenia Spectrum and Other Psychotic Disorders (25) · Mental Disorders (23) · Behavior (8) · Behavioral Symptoms (4) · Bipolar and Related Disorders (4) · Mood Disorders (4) · Social Behavior (4) · Depressive Disorder (3) · Personality Disorders (3) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Self-Control (2) · Signs and Symptoms (2)
Therapeutics (4) · Cognitive Behavioral Therapy (2) · Acceptance and Commitment Therapy (1) · Benztropine (1) · Cognitive Remediation (1) · Cycloserine (1) · Delivery of Health Care, Integrated (1) · Magnetic Resonance Spectroscopy (1) · Olanzapine (1) · Risperidone (1) · Rituximab (1) · Sugars (1) · agomelatine (1) · ziprasidone (1)
Centre for Addiction and Mental Health (2) · Philipps University Marburg (2) · VA Office of Research and Development (2) · AstraZeneca (1) · Beth Israel Deaconess Medical Center (1) · CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas (1) · Central Institute of Mental Health, Mannheim (1) · Columbia University (1) · London School of Hygiene and Tropical Medicine (1) · Max-Planck-Institute of Psychiatry (1) · Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital (1) · NYU Langone Health (1) · New York State Psychiatric Institute (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Research Foundation for Mental Hygiene, Inc. (1)
Germany (8) · United States (8) · Canada (2) · Brazil (1) · Denmark (1) · Finland (1) · Malawi (1) · Nigeria (1) · Portugal (1) · Sierra Leone (1) · Spain (1) · Sweden (1) · United Kingdom (1) · Zimbabwe (1)
Emily Treichler, PhD (2) · Ana Barajas Velez (1) · Ana E Marques Castro, M.Sc. (1) · Andreas Bechdolf, PD Dr. (1) · Andreas Bechdolf, Prof. Dr. (1) · Anne K Pagsberg, PhD (1) · Ariel Graff, MD (1) · Ariel Graff-Guerrero, MD,PhD (1) · David C. Mamo, MD MSc (1) · Donald C Goff, MD (1) · Janessa O Carvalho, Ph.D. (1) · Janet L Cunningham, MD PhD (1) · Joanna Moncrieff, MBBS (1)
PMID 24062154, PMID 24062155, PMID 25188752, PMID 27557949, PMID 28086010, PMID 28778554, PMID 29485988, PMID 31708810, PMID 31814102, PMID 32507378, PMID 33781352, PMID 36076205, PMID 37778356, PMID 38840160, PMID 41654084, PMID 42531158
2019 (1), K23MH126312 (1), R01MH127174 (1)