4 recruiting, 3 not yet recruiting, 2 completed, 1 active not recruiting. 5 Not applicable, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Recruiting 3, Completed 1, Not yet recruiting 1 |
| Phase 4 | 3 | Not yet recruiting 2, Completed 1 |
Follow Delayed Neurocognitive Recovery: new trials by email Literature Review of Delayed Neurocognitive Recovery trials Research Report on Delayed Neurocognitive Recovery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perioperative Transcranial Photobiomodulation and Delayed Neurocognitive Recovery in Older Patients Transcranial photobiomodulation therapy, Transcranial pseudo-photobiomodulation - Older Adults, Surgery | Not applicable | Recruiting | Peking University First Hospital | 130 | 2026-08-05 | 2026-08-10 |
| Targeted Temperature Management on Delayed Neurocognitive Recovery in Older Patients After Major Cancer Surgery Target temperature management, Routine thermal management - Elderly Patients, Cancer Surgery | Not applicable | Not yet recruiting | Peking University First Hospital | 1512 | 2026-06-01 | 2026-06-23 |
| Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients Esketamine 1, Esketamine 2, Esketamine 3 - Elderly, Noncardiac Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 120 | 2026-04-01 | 2026-04-14 |
| Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio Light anesthesia, Deep anesthesia - Elderly, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 200 | 2026-04-01 | 2026-03-18 |
| The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy POCD - Postoperative Cognitive Dysfunction, Recovery Time | Recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 60 | 2025-09-30 | 2026-06-09 | |
| Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery Ibuprofen (400 mg x 4), Placebo (NaCl 0.9 % solution) - Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery | Phase 4 | Completed | Mehmet Çiğdem | 76 | 2025-09-27 | 2026-03-03 |
| Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery Repetitive transcranial magnetic stimulation, Sham stimulation - Older Patients, Cognitive Impairment | Not applicable | Recruiting | Peking University First Hospital | 568 | 2025-07-28 | 2025-07-31 |
| Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Sleep Health Education - Insomnia, Postoperative Delirium | Not applicable | Recruiting | Massachusetts General Hospital | 50 | 2025-01-15 | 2026-09-14 |
| Study on the Characteristics of Non-targeted Metabolomics and EEG of Delayed Neurocognitive Recovery in Elderly Patients Collecting clinical data, EGG，arterial blood gas data and venous blood sample - Delayed Neurocognitive Recovery | Active not recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 80 | 2021-05-22 | 2023-07-18 | |
| Olfactory Function and Delayed Neurocognitive Recovery Odor Enrichment - Delayed Neurocognitive Recovery | Not applicable | Completed | Shanghai 10th People's Hospital | 131 | 2018-01-01 | 2025-07-31 |
Emergence Delirium (4) · Cognitive Dysfunction (1) · Hypothermia (1) · Neuroinflammatory Diseases (1) · Pain, Postoperative (1) · Postoperative Cognitive Complications (1) · Sleep Initiation and Maintenance Disorders (1)
Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Mental Disorders (5) · Nervous System Diseases (5) · Neurocognitive Disorders (5) · Neurologic Manifestations (5) · Pathologic Processes (5) · Postoperative Complications (5) · Confusion (4) · Delirium (4) · Neurobehavioral Manifestations (4) · Cognition Disorders (2) · Body Temperature Changes (1) · Cognitive Dysfunction (1) · Dyssomnias (1)
Ibuprofen (1) · Propofol (1) · Remifentanil (1) · Saline Solution (1) · Solutions (1) · Transcranial Magnetic Stimulation (1)
Peking University First Hospital (5) · Massachusetts General Hospital (1) · Mehmet Çiğdem (1) · Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital (1) · Shanghai 10th People's Hospital (1) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1)
China (7) · Turkey (Türkiye) (2) · United States (1)
Dong-Xin Wang, MD, PhD (3) · Dong-Xin U Wang (1) · Dong-Xin Wang (1) · Hong Jiang, Doctor (1) · Kun Hu, PhD (1) · Lei Gao, MD (1) · Nuray Turkut (1) · Yuan Shen (1)
PMID 29223575, PMID 33439974, PMID 37583434, PMID 38590312, PMID 40518008, PMID 42209013