49 completed, 14 terminated, 11 unknown, 5 withdrawn. 86 Phase 3, 18 Phase 2.
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| Inhaled Amikacin Versus Placebo in Patients With Ventilator-associated Tracheobronchitis Optimized and protocolized nebulization procedure. - Ventilator-Associated Pneumonia, Ventilator-Associated Tracheobronchitis | Phase 3 | Not yet recruiting | University Hospital, Tours | 250 | 2026-06-01 | 2026-06-24 |
| Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABP Cefepime-taniborbactam, Meropenem - Ventilator-associated Pneumonia, Hospital-acquired Pneumonia | Phase 3 | Withdrawn | Venatorx Pharmaceuticals, Inc. | 2025-06-01 | 2025-06-08 | |
| The Prophylactic Effect of Garlic Tablets to Prevent Nosocomial Infections in Intensive Care Unit Patients. Garlic powder standardized to allicin - Nosocomial Infection | Phase 3 | Enrolling by invitation | Alexandria University | 62 | 2025-03-01 | 2025-10-07 |
| Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype Dexamethasone, Placebo - Hospital Acquired Pneumonia | Phase 3 | Recruiting | Nantes University Hospital | 450 | 2024-03-26 | 2026-08-19 |
| Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL Acyclovir - Pneumonia, Viral, Ventilator Associated Pneumonia | Phase 3 | Recruiting | Jena University Hospital | 616 | 2024-02-20 | 2026-07-23 |
| Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit cotrimoxazole, standard antibiotic therapy - Ventilator Associated Pneumonia | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 628 | 2023-10-19 | 2025-05-20 |
| "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. Baricitinib 4 MG - Hospital-acquired Pneumonia | Phase 2 / Phase 3 | Unknown | Nantes University Hospital | 450 | 2023-07-01 | 2023-06-22 |
| Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients Interferon gamma, Placebo - Pneumonia, Ventilator-Associated | Phase 3 | Recruiting | Hospices Civils de Lyon | 132 | 2023-06-30 | 2026-07-06 |
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 Suvratoxumab, Placebo - Ventilator Associated Pneumonia, Staphylococcus Aureus | Phase 3 | Terminated | Aridis Pharmaceuticals, Inc. | 24 | 2022-09-02 | 2025-03-24 |
| Daily Chlorexidine Bath for Health Care Associated Infection Prevention 2% chlorhexidine digluconate solution with surface-active agents, Usual Baths - Health Care Associated Infection, Ventilator Associated Pneumonia | Phase 3 | Completed | Hospital do Coracao | 15730 | 2022-08-03 | 2024-06-13 |
| Management of Ventilation Acquired Pneumonia Caused by Pseudomonas and Acinetobacter Organisms in a Pediatric Center extended meropenem infusion in combination with other options such as Polymyxin, Tigecycline, Ertapenem, or Amikacin., two β-lactam antibiotics plus a single non-β-lactam antibiotic, Control group received standard therapy - Ventilation Acquired Pneumonia | Phase 3 | Completed | Beni-Suef University | 64 | 2021-01-01 | 2024-12-18 |
| Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 AR-301, Placebo - Lung Infection, Pneumonia, Ventilator-Associated | Phase 3 | Completed | Aridis Pharmaceuticals, Inc. | 174 | 2019-05-03 | 2023-07-06 |
| Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia Aztreonam lysine, Aerogen Solo, CombiHaler - Ventilator Associated Pneumonia, Prevention | Phase 2 / Phase 3 | Terminated | Hospital Universitari Joan XXIII de Tarragona. | 9 | 2019-03-19 | 2021-07-01 |
| Different Oral Colonization of Gram-negative Bacteria in ICU Patients When Using Chlorhexidine at 0.12% Versus Chlorhexidine at 2.0% Chlorhexidine gluconate at 2%, Chlorhexidine gluconate at 0.12% - Chlorhexidine, Ventilator Associated Pneumonia | Phase 3 | Unknown | Universidad de Guanajuato | 74 | 2019-02-01 | 2019-03-11 |
| Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients with Ventilator Associated-pneumonia 1 hour infusion, 4 hours infusion - Ventilator-associated Pneumonia | Phase 3 | Unknown | University Hospital, Toulouse | 80 | 2018-09-20 | 2024-09-25 |
| A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia Meropenem-Vaborbactam, Piperacillin/Tazobactam - Hospital-Acquired Bacterial Pneumonia, Ventilator-Associated Bacterial Pneumonia | Phase 3 | Withdrawn | Melinta Therapeutics, Inc. | 2018-08-01 | 2019-01-11 | |
| A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. ATM-AVI, MTZ, MER - Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia | Phase 3 | Completed | Pfizer | 422 | 2018-04-05 | 2024-12-10 |
| Defining Antibiotic Treatment Duration for Ventilator - Associated Lung Infection Reducing Antibiotics treatment duration, Standard Antibiotics treatment duration - Ventilator Associated Pneumonia, Pneumonia, Bacterial | Phase 3 | Completed | University of Oxford | 460 | 2018-02-21 | 2024-01-18 |
Showing 20 of 86. Sign in to see all of them.
Pneumonia, Ventilator-Associated (55) · Healthcare-Associated Pneumonia (24) · Pneumonia (19) · Pneumonia, Bacterial (8) · Sepsis (7) · Community-Acquired Pneumonia (5) · Community-Acquired Infections (4) · Staphylococcal Infections (4) · Bacteremia (3) · Infections (3) · Bacterial Infections (2) · Critical Illness (2) · Enterocolitis, Necrotizing (2) · Intraabdominal Infections (2)
Disease Attributes (86) · Iatrogenic Disease (86) · Pathologic Processes (86) · Pathological Conditions, Signs and Symptoms (86) · Infections (83) · Respiratory Tract Diseases (66) · Respiratory Tract Infections (66) · Lung Diseases (64) · Pneumonia (47) · Healthcare-Associated Pneumonia (40) · Bacterial Infections and Mycoses (17) · Bacterial Infections (15) · Inflammation (10) · Systemic Inflammatory Response Syndrome (10)
Colistin (6) · Doripenem (5) · Meropenem (5) · Tigecycline (5) · Linezolid (4) · Ceftazidime (3) · Saline Solution (3) · Vancomycin (3) · ceftobiprole (3) · ceftolozane, tazobactam drug combination (3) · colistinmethanesulfonic acid (3) · Amoxicillin-Potassium Clavulanate Combination (2) · Bronchoscopy (2) · Cefiderocol (2) · Ciprofloxacin (2)
Assistance Publique - Hôpitaux de Paris (4) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (4) · Wyeth is now a wholly owned subsidiary of Pfizer (4) · Basilea Pharmaceutica (3) · Pfizer (3) · Aridis Pharmaceuticals, Inc. (2) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (2) · Hospital Universitari Joan XXIII de Tarragona. (2) · Nantes University Hospital (2) · Rabin Medical Center (2) · Rennes University Hospital (2) · Shionogi (2) · University Hospital, Tours (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alexandria University (1)
France (23) · United States (15) · Spain (13) · Israel (9) · Italy (8) · Thailand (7) · Brazil (6) · China (6) · Mexico (6) · Ukraine (6) · Belgium (5) · Germany (5) · India (5) · Japan (5) · Russia (5)
Philippe Seguin, MD, PhD (2) · Aaron Milstone, MD MHS (1) · Alexandre B Cavalcanti, M.D (1) · Alfredo Guarino, MD (1) · Anil Sachdev, MD (1) · Anthony Gordon, MD FRCA (1) · Avery B Nathens, MD PhD MPH (1) · Bekele Afessa, MD (1)
PMID 18508226, PMID 19036670, PMID 19670912, PMID 20211892, PMID 20459721, PMID 24723282, PMID 30808293, PMID 33960817, PMID 34155899, PMID 34792787, PMID 35076335, PMID 41251370, PMID 10816031, PMID 12749509, PMID 16236177, PMID 16980879, PMID 17076839, PMID 17119142, PMID 17872488, PMID 18461895, PMID 18549664, PMID 18641114, PMID 18714060, PMID 18990531, PMID 19036672, PMID 19467544, PMID 19482956, PMID 19740418, PMID 20302428, PMID 20407057, PMID 20522788, PMID 20522796, PMID 20663130, PMID 20936977, PMID 21129208, PMID 21558772, PMID 22186217, PMID 22306046, PMID 22488002, PMID 22760426, PMID 22812672, PMID 23071204, PMID 23148736, PMID 23352693, PMID 23363666, PMID 23583261, PMID 23616495, PMID 23727136, PMID 24105456, PMID 24207137
2016 (2), 2009 (1), 2015 (1), 2017 (1), 2018 (1), 2023 (1), P50HL073996 (1)