35 completed. 35 Phase 2, 6 Phase 3, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 35 | Completed 35 |
| Phase 3 | 6 | Completed 6 |
| Phase 1 | 4 | Completed 4 |
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB BV100 plus Polymyxin B, BAT - Ventilator Associated Pneumonia | Phase 2 | Completed | BioVersys AG | 39 | 2023-04-20 | 2025-01-14 |
| Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia Anakinra Prefilled Syringe, Placebo - Community-acquired Pneumonia, Hospital-acquired Pneumonia | Phase 2 | Completed | Hellenic Institute for the Study of Sepsis | 60 | 2023-03-06 | 2024-07-31 |
| Red Light Photobiomodulation and Topical Disinfectants Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate - Healthcare Associated Infection, Nosocomial Infection | Phase 1 / Phase 2 | Completed | Ondine Biomedical Inc. | 28 | 2023-01-10 | 2023-04-04 |
| Intravenous Metoprolol in Septic Shock Intravenous metoprolol tartrate, Standard Care (in control arm) - Septic Shock, Ventilator Acquired Pneumonia | Phase 2 | Completed | Alexandria University | 100 | 2022-04-01 | 2025-01-29 |
| Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation - Surgical Site Infections, Nosocomial Infection | Phase 2 | Completed | Ondine Biomedical Inc. | 322 | 2022-02-04 | 2022-08-22 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants Cefiderocol, Standard of Care - Gram-negative Bacterial Infections, Bloodstream Infections (BSI) | Phase 2 | Completed | Shionogi | 53 | 2020-08-21 | 2026-02-27 |
| Inulin for Infections in the Intensive Care Unit Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics - Antibiotic Resistant Infection, Nosocomial Infection | Phase 2 | Completed | Columbia University | 94 | 2019-10-14 | 2025-06-19 |
| Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia EVAC-PU-ETT, PVC-ETT - Ventilator-acquired Pneumonia | Phase 2 | Completed | Yale University | 1074 | 2019-05-06 | 2024-09-24 |
| Coated Devices to Decrease Infection in the Intensive Care Unit Coated devices, Control - Critically Ill | Phase 1 / Phase 2 | Completed | Hospital do Coracao | 103 | 2019-04-06 | 2020-03-09 |
| Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia methylprednisolone, Methyl Prednisolonate, ventilators - Ventilator Associated Pneumonia | Phase 2 | Completed | King Abdul Aziz Specialist Hospital | 240 | 2018-01-02 | 2020-07-13 |
| The Effect of Colistin Inhalation on Ventilator Associated Pneumonia Colistin, Carbapenem + Aminoglycoside/ Quinolone - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Nourhan Hassan Osama Thuraya Mohamed | 40 | 2016-01-02 | 2018-08-09 |
| Atropine for Preventing Ventilator-Associated Pneumonia Atropine, Placebo - Ventilator-Associated Pneumonia | Phase 2 | Completed | Universidade de Passo Fundo | 40 | 2015-02-01 | 2016-03-10 |
| Clinical Trial Evaluating Chlorine e6 Derivative-mediated Antimicrobial Photodynamic Therapy as a Treatment for Denture Stomatitis Nystatin, Antimicrobial Photodynamic Therapy - Health Care Associated Infection | Phase 2 | Completed | São Paulo State University | 65 | 2015-02-01 | 2020-08-31 |
| Methods of Chlorhexidine Cleansing to Prevent Ventilator-Associated Pneumonia (VAP) Chlorhexidine, 0.9% sodium chloride injection, Endotracheal tube - Ventilator-associated Pneumonia | Phase 2 | Completed | General Hospital of Shenyang Military Region | 192 | 2014-03-01 | 2019-08-14 |
| Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia POL7080 - Ventilator Associated Pneumonia, Lower Respiratory Infection | Phase 2 | Completed | Polyphor Ltd. | 25 | 2013-10-01 | 2017-11-28 |
| Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial L. rhamnosus GG - Probiotic, Placebo - Microcrystalline Cellulose - Ventilator Associated Pneumonia (VAP), Other Infections | Phase 2 | Completed | McMaster University | 150 | 2013-10-01 | 2019-08-28 |
| Vitamin D in Ventilated ICU Patients Enteral Vitamin D3 50,000 IU, Enteral Vitamin D3 100,000IU, Inactive substance - Respiratory Failure | Phase 2 | Completed | Emory University | 31 | 2011-07-01 | 2017-01-09 |
| Prevention of Nosocomial E. Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: an Evaluation of Cranberry Gel Capsules cranberry type A pro anthocyandines, Placebo - Cross Infection, Bacteriuria | Phase 2 | Completed | Centre Hospitalier Universitaire de Nīmes | 270 | 2010-08-01 | 2025-11-17 |
| Study Assessing Immunogenicity and Safety of IC43 In Intensive Care Patients IC43, Placebo - Pneumonia, Ventilator-Associated | Phase 2 | Completed | Valneva Austria GmbH | 400 | 2008-12-01 | 2012-10-19 |
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Pneumonia, Ventilator-Associated (22) · Pneumonia (11) · Infections (5) · Sepsis (5) · Healthcare-Associated Pneumonia (4) · Pseudomonas Infections (4) · Surgical Wound Infection (4) · Bacterial Infections (3) · Critical Illness (3) · Fever (2) · Pneumonia, Bacterial (2) · Respiratory Tract Infections (2) · Abdominal Abscess (1) · Bacteriuria (1)
Disease Attributes (35) · Iatrogenic Disease (35) · Pathologic Processes (35) · Pathological Conditions, Signs and Symptoms (35) · Infections (30) · Respiratory Tract Diseases (27) · Lung Diseases (25) · Respiratory Tract Infections (24) · Healthcare-Associated Pneumonia (19) · Pneumonia (14) · Bacterial Infections and Mycoses (9) · Inflammation (7) · Bacterial Infections (6) · Systemic Inflammatory Response Syndrome (6)
Chlorhexidine (2) · Doripenem (2) · Standard of Care (2) · chlorhexidine gluconate (2) · 1-phenyl-3,3-dimethyltriazene (1) · Amikacin (1) · Aminoglycosides (1) · Anti-Bacterial Agents (1) · Atropine (1) · Carbapenems (1) · Cefiderocol (1) · Ceftazidime (1) · Cilastatin, Imipenem Drug Combination (1) · Ciprofloxacin (1) · ClinOleic (1)
Emory University (2) · Ondine Biomedical Inc. (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alexandria University (1) · BioVersys AG (1) · Canadian Critical Care Trials Group (1) · Centre Hospitalier Universitaire de Nīmes (1) · Columbia University (1) · General Hospital of Shenyang Military Region (1) · Groupe Hospitalier Pitie-Salpetriere (1) · Hellenic Institute for the Study of Sepsis (1) · Hospital do Coracao (1) · Humanigen, Inc. (1) · Johns Hopkins University (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1)
United States (14) · France (4) · Canada (3) · Greece (3) · Egypt (2) · Georgia (2) · Hungary (2) · Russia (2) · Spain (2) · Ukraine (2) · Argentina (1) · Austria (1) · Belgium (1) · Brazil (1) · Chile (1)
Aaron Milstone, MD MHS (1) · Alexandre Biasi, MD/PhD (1) · Antoni Torres, MD PhD (1) · Avery B Nathens, MD PhD MPH (1) · Cindy L Munro, RN,ANP,PHD (1) · Cindy Munro, RN, ANP,PhD (1) · Daniel E Freedberg, MD, MS (1) · Deborah J Cook, MD (1) · Evangelos Giamarellos-Bourboulis, MD PhD (1) · Evangelos Giamarellos-Bourboulis, MD, PhD (1) · Frank A. Scannapieco, DMD PhD (1) · Greg Martin, MD, MSc (1) · Guillermo Umpierrez, MD (1) · Hazem E Elsersy, MD (1) · Jean-Jacques Rouby, MD, PhD (1)
PMID 16980879, PMID 17076839, PMID 17119142, PMID 18461895, PMID 18991508, PMID 19765321, PMID 22488002, PMID 23363666, PMID 25317722, PMID 27419080, PMID 27480757, PMID 27965798, PMID 28159015, PMID 28186383, PMID 30526610, PMID 32526149, PMID 32595159, PMID 36289153, PMID 37068952, PMID 37947276, PMID 38676438, PMID 39230271, PMID 39806400, PMID 40237647, PMID 41319662, PMID 41552367, PMID 42047567, PMID 42497015
R01NR007652 (2), 2019 (1), P50HL073996 (1), R01DE014685 (1), R33HL138650 (1)