6 completed, 3 unknown, 2 recruiting. 5 Phase 2, 4 Phase 3, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Unknown 3, Completed 1, Recruiting 1 |
| Phase 3 | 4 | Completed 2, Unknown 2 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Carbapenems: new trials by email Literature Review of Carbapenems trials Research Report on Carbapenems
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cefotetan Therapy for Escherichia Coli Infections Cefotetan, Carbapenems, Beta Lactam Antibiotics - E Coli Infection, ESBL Producing E.Coli | Phase 2 | Recruiting | Oregon Health and Science University | 50 | 2026-06-26 | 2026-10-16 |
| Efficacy of Empirical Anti-Infective Therapy in Neutropenic Febrile Patients. Carbapenems, Anti-Gram-positive agent, Antifungal agent - Febrile Neutropenia | Recruiting | Shanxi Bethune Hospital | 20 | 2025-09-22 | 2025-10-02 | |
| Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia Ertapenem, Carbapenems - Bacteremia, Infection, Bacterial | Completed | Phramongkutklao College of Medicine and Hospital | 427 | 2019-05-15 | 2023-03-29 | |
| Temocillin Versus a Carbapenem as Initial Intravenous Treatment for ESBL Related Urinary Tract Infections Temocillin, meropenem or imipenem - Urinary Tract Infections | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 29 | 2019-01-04 | 2025-11-20 |
| suPAR to Guide Antibiotics in Emergency Department Meropenem, Placebo - Sepsis | Phase 2 / Phase 3 | Unknown | Hellenic Institute for the Study of Sepsis | 220 | 2018-10-27 | 2020-07-30 |
| Evidence Based Management of Acute Biliary Pancreatitis serum lipase or amylase, ultrasound, CT - Acute Pancreatitis | Completed | Zagazig University | 30 | 2017-05-15 | 2020-11-05 | |
| Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections Vabomere - Bacterial Infections | Phase 1 | Completed | Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) | 39 | 2016-07-01 | 2026-08-17 |
| Furosemide Stress Test Guiding Initiation of Renal Replacement Therapy Dialysis with continuous renal replacement therapy, Mechanical ventilator, Anti-Bacterial Agents - Acute Kidney Injury | Not applicable | Completed | Chulalongkorn University | 118 | 2016-03-01 | 2017-12-19 |
| The Effect of Colistin Inhalation on Ventilator Associated Pneumonia Colistin, Carbapenem + Aminoglycoside/ Quinolone - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Nourhan Hassan Osama Thuraya Mohamed | 40 | 2016-01-02 | 2018-08-09 |
| Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock glycopeptide plus carbapenem, Haizheng Li Xing ® plus tazocin ® - Abdominal Infection | Phase 2 / Phase 3 | Unknown | Tianjin Medical University Cancer Institute and Hospital | 100 | 2014-05-01 | 2014-07-16 |
| Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli Sitafloxacin, Ertapenem - Infection Due to Escherichia Coli, Acute Pyelonephritis | Phase 2 | Unknown | Mahidol University | 96 | 2012-11-01 | 2015-09-02 |
Bacterial Infections (2) · Escherichia coli Infections (2) · Acute Kidney Injury (1) · Bacteremia (1) · Febrile Neutropenia (1) · Intraabdominal Infections (1) · Pancreatitis (1) · Pneumonia, Ventilator-Associated (1) · Sepsis (1) · Urinary Tract Infections (1)
Assistance Publique - Hôpitaux de Paris (1) · Chulalongkorn University (1) · Hellenic Institute for the Study of Sepsis (1) · Mahidol University (1) · Nourhan Hassan Osama Thuraya Mohamed (1) · Oregon Health and Science University (1) · Phramongkutklao College of Medicine and Hospital (1) · Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) (1) · Shanxi Bethune Hospital (1) · Tianjin Medical University Cancer Institute and Hospital (1) · Zagazig University (1)
Thailand (3) · China (2) · United States (2) · Egypt (1) · France (1) · Greece (1)
Evangelos Giamarellos-Bourboulis, MD, PhD (1) · Nattachai Srisawat, MD (1) · Sasisopin Kiertiburanakul (1) · Wang Donghao, Chief (1)
PMID 17359318, PMID 23772043, PMID 23896955, PMID 24054878, PMID 25904407, PMID 29673370, PMID 33534419, PMID 36416787, PMID 37252945, PMID 38321472, PMID 39964222
2016 (1), 2017 (1)