10 completed, 2 terminated, 2 unknown, 1 withdrawn. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 10, Terminated 2, Unknown 2, Withdrawn 1 |
Follow Critically Ill: new trials by email Literature Review of Critically Ill trials Research Report on Critically Ill
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Colistin Intravenous Administration in Critically Ill Patients Suffering From Hospital Infections Caused by Multi-antibiotic-resistant Germs. Colistin - Hospital Infection, Multi-antibiotic Resistance | Phase 4 | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2021-07-14 | 2021-08-06 |
| The Association of Vitamin D Supplementation With the Outcome in Critically Ill Children Vitamin D, Normal saline - Critically Ill | Phase 4 | Completed | Dr Mustahsin Khalil | 96 | 2019-08-29 | 2020-09-03 |
| Ketamine-fentanyl VS Fentanyl for Analgosedation in SICU Ketamine, Normal saline - Critically Ill, Pain, Postoperative | Phase 4 | Completed | Mahidol University | 118 | 2019-04-05 | 2024-07-15 |
| Ceftaroline Pharmacokinetics in Continuous Renal Replacement Therapy Ceftaroline levels in CRRT - Infection During Renal Replacement Therapy, Critically Ill | Phase 4 | Completed | University of Maryland, Baltimore | 4 | 2018-03-09 | 2021-03-18 |
| Randomized Trial of Continuous Versus Intermittent Cefotaxime Infusion on ICU. Cefotaxime - Critically Ill | Phase 4 | Completed | University Medical Center Groningen | 60 | 2015-11-01 | 2016-10-27 |
| PEP uP Protocol in Surgical Patients PEP uP Protocol, Metoclopramide - Critically Ill | Phase 4 | Terminated | Clinical Evaluation Research Unit at Kingston General Hospital | 36 | 2015-07-01 | 2020-10-27 |
| Bioavailability of Voriconazole Dosage form of voriconazole - Voriconazole, Bioavailability | Phase 4 | Withdrawn | University Medical Center Groningen | 2015-06-01 | 2016-09-02 | |
| Leptin and Ghrelin in ICU enteral feeding by nasogastric tube. - Critically Ill | Phase 4 | Completed | özgür yağan | 40 | 2014-08-01 | 2016-03-29 |
| Optimal Dosage of Caspofungin in Critically Ill Patients Caspofungin - Critically Ill, Suspected Invasive Candidiasis | Phase 4 | Completed | University Medical Center Groningen | 20 | 2013-11-01 | 2015-10-30 |
| Efficiency of a Small-peptide Enteral Feeding Formula Compared to a Whole-protein Formula Peptamen® AF, Sondalis® HP - Traumatic and/or Non-traumatic Brain Injury, Critically Ill | Phase 4 | Unknown | Centre Hospitalier Universitaire de Besancon | 206 | 2012-06-01 | 2016-08-05 |
| Directed Immuno Nutrition by L-arginine for Critically Ill Patients L-arginine, placebo - Critically Ill | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 30 | 2009-11-01 | 2013-09-18 |
| Continuous Control of Tracheal Cuff Pressure and Microaspiration in Critically Ill Patients Continuous control of cuff pressure, Manual control of cuff pressure - Critically Ill | Phase 4 | Completed | University Hospital, Lille | 122 | 2009-10-01 | 2026-04-22 |
| Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients Potassium Chloride - Thoracic Surgery, Cardiac Surgery | Phase 4 | Completed | University Medical Center Groningen | 1225 | 2009-06-01 | 2013-01-21 |
| Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD) Daptomycin - Critically Ill, Hemodialysis | Phase 4 | Completed | University of Michigan | 8 | 2007-02-01 | 2015-12-30 |
| Enteral Versus Parenteral Glutamine Supplement parenteral glutamine, enteral glutamine - Critically Ill | Phase 4 | Terminated | University Medical Centre Ljubljana | 90 | 2004-10-01 | 2014-01-16 |
Critical Illness (15) · Cross Infection (2) · Atrial Fibrillation (1) · Brain Injuries (1) · Infections (1) · Pain, Postoperative (1)
Disease Attributes (15) · Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Iatrogenic Disease (2) · Infections (2) · Arrhythmias, Cardiac (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Craniocerebral Trauma (1) · Heart Diseases (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Pain (1) · Postoperative Complications (1)
Saline Solution (2) · Arginine (1) · Caspofungin (1) · Cefotaxime (1) · Cholecalciferol (1) · Colistin (1) · Daptomycin (1) · Ketamine (1) · Metoclopramide (1) · Potassium Chloride (1) · Vitamin D (1) · alanylglutamine (1)
University Medical Center Groningen (4) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire de Besancon (1) · Clinical Evaluation Research Unit at Kingston General Hospital (1) · Dr Mustahsin Khalil (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Mahidol University (1) · University Hospital, Lille (1) · University Medical Centre Ljubljana (1) · University of Maryland, Baltimore (1) · University of Michigan (1) · özgür yağan (1)
Netherlands (4) · France (3) · United States (3) · Italy (1) · Pakistan (1) · Slovenia (1) · Thailand (1) · Turkey (Türkiye) (1)
Jan-Willem Alffenaar, PharmD, PhD (2) · Alain Durocher, MD (1) · Bruce A Mueller, PharmD (1) · Daren K Heyland, MD (1) · Farid Zerimech, MD (1) · Felix Zijlstra, MD/PhD (1) · Gilles Blasco (1) · Jan G Zijlstra, MD, PhD (1) · Jasna Uranjek, MD (1) · Maarten WN Nijsten, MD/PhD (1) · Malika Balduyck, MD (1) · Mojdeh Heavner (1)
PMID 18626628, PMID 20890189, PMID 21194419, PMID 21836137, PMID 23778831, PMID 26856215, PMID 27855112, PMID 31697336, PMID 39340688, PMID 39908192