124 completed, 57 unknown, 15 terminated, 12 recruiting. 66 Not applicable, 23 Phase 2, 15 Phase 4, 12 Phase 3, 6 Phase 1.
Follow Critically Ill: new trials by email Literature Review of Critically Ill trials Research Report on Critically Ill
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients induction type for intubation in ICU - Critically Ill, Intubation Complication | Completed | Zeliha Alicikus | 806 | 2026-04-18 | 2026-10-08 | |
| Transducer Levelling Errors in Everyday ICU Practice - A Multicentre Blinded Observational Study Critically Ill, Haemodynamic Instability | Recruiting | Vastra Gotaland Region | 60 | 2026-02-01 | 2026-07-07 | |
| Factor Associated With Mortality in the ICU Exposure factors - Critically Ill, Intensive Care (ICU) | Recruiting | Hospital Departamental de Villavicencio | 1000 | 2026-01-10 | 2026-05-27 | |
| Analgesia Nociception Index to Explore Autonomic Nervous System in Patients With Continuous Renal Replacement Therapy Critically Ill, Renal Replacement Therapy | Recruiting | Hospices Civils de Lyon | 30 | 2026-01-09 | 2026-01-15 | |
| Fluid Balance in Acute Kidney Injury in Critically Ill Patients Fluid Balance, Acute Kidney Injury | Not yet recruiting | Assiut University | 120 | 2026-01-01 | 2026-01-14 | |
| Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion Parasternal intercostal thickening fraction, Sham parasternal intercostal thickening - Critically Ill | Not applicable | Recruiting | Cairo University | 200 | 2025-09-01 | 2025-09-08 |
| "Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools" mini_FC - Sepsis, Shock, Septic | Not yet recruiting | Humanitas Clinical and Research Center | 45 | 2025-08-01 | 2025-06-29 | |
| Efficacy of SGLT2 Inhibitors in Adults With Sepsis Empagliflozin 10 MG, Placebo - Sepsis, Inflammation | Not applicable | Recruiting | Hospital Authority, Hong Kong | 60 | 2025-03-05 | 2025-03-19 |
| Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients--Protocol for a Delphi Study Delphi Study - Critically Ill, Ventilation Therapy; Complications | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 35 | 2024-11-12 | 2026-02-20 | |
| Clinical Outcomes Of Mega-dosage Supplementations Of Cholecalciferol In Critically Ill Patients With Sepsis Placebo, Cholecalciferol - Critically Ill, Sepsis | Not applicable | Not yet recruiting | Chimei Medical Center | 240 | 2024-07-01 | 2024-06-17 |
| Empirical Meropenem Dosing in Critically Ill Patients: Early Assessment of Plasma Exposure and Minimum Inhibitory Concentration Targets Blood extraction - Empirical Antimicrobial Therapy, Critically Ill | Not applicable | Completed | Hospital Italiano de Buenos Aires | 26 | 2024-06-26 | 2026-07-08 |
| Impact of Rapid Pathogen Detection in ICU Patients With Suspected Pneumonia on Antimicrobial Therapy FA Pneumonia Panel - Pneumonia, Critically Ill | Phase 2 | Completed | Chinese University of Hong Kong | 40 | 2024-06-26 | 2026-03-06 |
| Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy Macrohemodynamic parameters - Fluid Removal, Critically Ill | Unknown | Hospices Civils de Lyon | 60 | 2024-06-01 | 2024-05-22 | |
| Continuous Temperature Measurement by Thermal Imaging Camera Critically Ill | Unknown | Universidad Europea de Madrid | 224 | 2024-03-01 | 2024-02-13 | |
| Dynamic Full-field Optical Coherence Tomography for Structural and Microbiological Characterization of Endotracheal Tube Biofilm in Critically Ill Patients •Dynamic Full-Field Optical Coherence Tomography analysis of endotracheal tube - Healthcare Associated Infection, Critically Ill | Unknown | Centre Hospitalier Universitaire Dijon | 80 | 2024-03-01 | 2024-04-23 | |
| Indirect Calorimetry Versus Urea-creatinine Ratio to Evaluate Catabolism in Critically Ill Patients Critically Ill | Completed | Hospital Sao Domingos | 20 | 2024-03-01 | 2025-02-19 | |
| Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children NAVA - Mechanical Ventilator Weaning, Critically Ill | Not applicable | Unknown | Chulalongkorn University | 60 | 2024-02-01 | 2023-12-06 |
| Ultrasound to Evaluate Acute Kidney Injury Acute Kidney Injury, Critically Ill | Unknown | Southeast University, China | 50 | 2024-01-25 | 2024-02-05 | |
| Central Venous Pressure and Right Atrial Pressure Measurements in Supine, Semi-recumbent and Trendelenburg Position Critically Ill | Completed | Vastra Gotaland Region | 16 | 2023-11-15 | 2025-05-20 | |
| Comparison of Body Weights Via Visual Estimation, Anthropometric Calculation, and Actual Measured in Critically Ill Patients patient transfer scale - Critically Ill, Body Weight | Not applicable | Completed | Gazi University | 200 | 2023-11-01 | 2025-03-13 |
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Critical Illness (217) · Sepsis (18) · Acute Kidney Injury (15) · COVID-19 (9) · Shock, Septic (8) · Infections (7) · Cross Infection (4) · Pneumonia, Ventilator-Associated (4) · Shock (4) · Candidiasis, Invasive (3) · Heart Diseases (3) · Hyperglycemia (3) · Hyperphagia (3) · Inflammation (3) · Multiple Organ Failure (3)
Disease Attributes (217) · Pathologic Processes (217) · Pathological Conditions, Signs and Symptoms (217) · Infections (42) · Respiratory Tract Diseases (25) · Systemic Inflammatory Response Syndrome (20) · Inflammation (19) · Female Urogenital Diseases and Pregnancy Complications (18) · Lung Diseases (18) · Urogenital Diseases (18) · Female Urogenital Diseases (17) · Kidney Diseases (17) · Male Urogenital Diseases (17) · Signs and Symptoms (17) · Urologic Diseases (17)
Echocardiography (3) · Saline Solution (3) · Calorimetry, Indirect (2) · Cholecalciferol (2) · Continuous Renal Replacement Therapy (2) · Methadone (2) · Methods (2) · Nutrition Therapy (2) · Standard of Care (2) · Surveys and Questionnaires (2) · Thiamine (2) · alanylglutamine (2) · ACE-011 (1) · Acetaminophen (1) · Acetylcysteine (1)
University Medical Center Groningen (7) · Australian and New Zealand Intensive Care Research Centre (6) · Central Hospital, Nancy, France (5) · Unity Health Toronto (5) · Helsinki University Central Hospital (4) · University of Ulm (4) · Assiut University (3) · Daren K. Heyland (3) · Hospital Sao Domingos (3) · Mahidol University (3) · University of Michigan (3) · Zhongda Hospital (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Amsterdam UMC, location VUmc (2) · Assistance Publique - Hôpitaux de Paris (2)
United States (34) · France (31) · Canada (17) · Netherlands (16) · China (15) · Australia (13) · Italy (10) · Brazil (8) · Germany (8) · Switzerland (7) · Egypt (6) · New Zealand (6) · Thailand (6) · Belgium (5) · Finland (5)
Daren K Heyland, MD (5) · Manfred Weiss, MD, MBA (3) · Alan H Morris, MD (2) · Benjamin S Bassin, MD (2) · Carol L Hodgson, PhD (2) · Davide Chiumello, MD (2) · Jan-Willem Alffenaar, PharmD, PhD (2) · Karen Burns, MD, FRCPC (2) · Mohan Gurjar, MD, PDCC (2) · A Beishuizen, MD PhD (1) · Abele Donati, MD, PhD (1) · Agussalim Bukhari, MD, Ph.D (1) · Alain Durocher, MD (1) · Alexander Zarbock, MD (1) · Alexandre Biasi, MD/PhD (1)
PMID 30920411, PMID 39382222, PMID 10861149, PMID 11098963, PMID 11281863, PMID 1144940, PMID 12460250, PMID 14608459, PMID 15883741, PMID 16310609, PMID 17470624, PMID 17873200, PMID 18626628, PMID 18778528, PMID 19114909, PMID 20124884, PMID 20170830, PMID 20429886, PMID 20663183, PMID 20890189, PMID 21194419, PMID 21836137, PMID 22102646, PMID 22339896, PMID 22981532, PMID 23218813, PMID 23363492, PMID 23641924, PMID 23641946, PMID 23653182, PMID 23688301, PMID 23776701, PMID 23778831, PMID 24165173, PMID 24276033, PMID 24389357, PMID 24748597, PMID 24887445, PMID 25045579, PMID 25046131, PMID 25317090, PMID 25466314, PMID 25487797, PMID 25645668, PMID 25745357, PMID 25901550, PMID 26201718, PMID 26306719, PMID 26785953, PMID 26856215
2009 (1), K23DK106448 (1), R01NR013664 (1), U24TR001608 (1)