18 completed, 4 recruiting, 3 unknown, 3 withdrawn. 12 Phase 2, 9 Not applicable, 7 Phase 4, 4 Phase 3, 1 Phase 1.
Follow Potassium Chloride: new trials by email Literature Review of Potassium Chloride trials Research Report on Potassium Chloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of Pregnancy Eplerenone 100 mg daily, Chlorthalidone 25 mg daily, Potassium Placebo - Hypertension | Phase 2 | Recruiting | Massachusetts General Hospital | 90 | 2026-03-20 | 2026-10-20 |
| Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial Golytely, Sulfave, Sutab - Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy | Phase 4 | Recruiting | Morehouse School of Medicine | 300 | 2025-10-01 | 2025-10-09 |
| Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation Potassium chloride - Out-of-hospital Cardiac Arrest (OHCA) | Phase 2 | Withdrawn | Assistance Publique - Hôpitaux de Paris | 2023-12-01 | 2025-11-20 | |
| Potassium Intake-response Trial to Control Hypertension Potassium Chloride, Placebo - Blood Pressure | Not applicable | Terminated | Tulane University | 25 | 2023-03-29 | 2026-06-08 |
| SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin - Heart Failure With Preserved Ejection Fraction | Phase 2 | Recruiting | University of Pennsylvania | 53 | 2022-01-24 | 2026-04-16 |
| Matching Perfusion and Metabolic Activity in HFpEF Potassium Nitrate, Potassium Nitrate + Propionyl-L-Carnitine + Nicotinamide Riboside, Potassium Chloride - Heart Failure With Preserved Ejection Fraction | Phase 2 | Recruiting | University of Pennsylvania | 53 | 2021-10-11 | 2026-06-02 |
| The Impact of Air Travel on Passenger Cognitive Functions Citicoline, Cytochrome C6, Sodium Chloride Oral Product - Air Travel | Phase 2 / Phase 3 | Unknown | Dinara Zhumanbayeva | 50 | 2021-06-01 | 2021-03-17 |
| Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity Eplerenone, Chlorthalidone with potassium chloride - Metabolic Syndrome, Hypertension | Phase 4 | Completed | Brigham and Women's Hospital | 79 | 2020-12-01 | 2026-09-15 |
| NATriuretic Response to Expansion and dIUretics in huMans With Heart Failure Ringer's (8.6 g/L sodium chloride, 0.33 g/L calcium chloride, 0.3 g/L potassium chloride) Solution, Intravenous Bolus Furosemide - Heart Failure | Not applicable | Completed | Momentum Research, Inc. | 229 | 2020-04-01 | 2022-04-18 |
| Study of the Efficacy and Safety of Quiklean® and Klean-Prep With Dulcolax® for the Bowel Preparation Prior to Colonoscopy Quiklean® (sodium phosphate monobasic monohydrate, USP, and sodium phosphate dibasic anhydrous, USP), Polyethylene glycol 3350, sodium sulfate anhydrous, sodium bicarbonate, sodium chloride, potassium chloride, aspartame;Bisacodyl - Bowel Preparation | Phase 3 | Completed | Universal Integrated Corp. | 472 | 2019-06-10 | 2020-03-30 |
| The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy Potassium Nitrate, Potassium Chloride - Contrast-induced Nephropathy, Acute Kidney Injury | Phase 2 | Completed | Barts & The London NHS Trust | 640 | 2018-11-29 | 2022-12-16 |
| The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics isotonic saline 9%, Potassium nitrate, Potassium chloride - Hypertension | Not applicable | Completed | Frank Mose | 18 | 2018-09-01 | 2021-02-21 |
| Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS) Potassium Nitrate, Potassium Chloride - Aortic Valve Stenosis | Phase 2 | Completed | University of Pennsylvania | 5 | 2018-05-01 | 2020-06-17 |
| Fetal Reduction: Mechanical vs Chemical Transvaginal ultrasound, Mechanical fetal reduction, Chemical fetal reduction - Multiple Pregnancy | Not applicable | Completed | Cairo University | 50 | 2017-08-01 | 2020-10-27 |
| Potassium Supplementation in CKD Potassium Chloride, Potassium Citrate, Placebo - Renal Insufficiency, Chronic, Potassium Depletion | Not applicable | Active not recruiting | Erasmus Medical Center | 532 | 2017-07-01 | 2026-08-10 |
| Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy Fetal Selective Reduction Technology, Potassium Chloride - Chromosome Abnormality, Twin Pregnancy With Antenatal Problem | Not applicable | Unknown | Shanghai First Maternity and Infant Hospital | 1300 | 2017-01-01 | 2016-12-05 |
| Fluid Therapy During Brain Tumor Resection in Children balanced crystalloid solution (components: sodium chloride, sodium gluconate, sodium acetate, potassium chloride and magnesium chloride), 0.9% sodium chloride - Brain Neoplasms | Phase 2 | Completed | Federal University of São Paulo | 53 | 2015-08-01 | 2017-11-14 |
| Prevention of Severe Postpartum Hypertension Furosemide, Potassium chloride, Placebo #1 - Hypertension | Phase 2 | Withdrawn | Indiana University | 2015-08-01 | 2023-05-11 | |
| Blood Pressure Regulation - Role of Potassium Kaleorid, 750mg (trade name), Potassium chloride (active substance), Placebo - Blood Pressure, Hypertension | Phase 4 | Completed | Glostrup University Hospital, Copenhagen | 25 | 2015-03-01 | 2017-01-06 |
| Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF KNO3, KCl - Heart Failure, Diastolic Heart Failure | Phase 2 | Completed | University of Pennsylvania | 12 | 2015-01-01 | 2017-10-03 |
Showing 20 of 31. Sign in to see all of them.
Hypertension (8) · Atrial Fibrillation (2) · Heart Failure (2) · Hypertension, Pregnancy-Induced (2) · Hypokalemia (2) · Pre-Eclampsia (2) · Acid-Base Imbalance (1) · Acidosis (1) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Aortic Valve Stenosis (1) · Atrial Flutter (1) · Bone Diseases (1) · Bone Diseases, Metabolic (1) · Brain Neoplasms (1)
University of Pennsylvania (4) · Aga Khan University (1) · Assistance Publique - Hôpitaux de Paris (1) · Barts & The London NHS Trust (1) · Brigham and Women's Hospital (1) · Cairo University (1) · Cardiff University (1) · Diakonhjemmet Hospital (1) · Dinara Zhumanbayeva (1) · Erasmus Medical Center (1) · Federal University of São Paulo (1) · Florida State University (1) · Frank Mose (1) · Glostrup University Hospital, Copenhagen (1) · Indiana University (1)
United States (14) · United Kingdom (3) · Denmark (2) · France (2) · Netherlands (2) · Armenia (1) · Bosnia and Herzegovina (1) · Brazil (1) · Czechia (1) · Egypt (1) · Germany (1) · Italy (1) · Norway (1) · Pakistan (1) · Poland (1)
Payman Zamani, MD (2) · Alexandre Mebazaa, MD PhD FESC (1) · Amrita Ahluwalia, PhD (1) · Anand Vaidya, MD (1) · Anwarul Haq, MD (1) · Bess Dawson-Hughes, MD (1) · Colin M Dayan, MA FRCP PhD (1) · Elizabeth B Ripley, MD (1) · Ewout J Hoorn, MD, PhD (1) · Felix Zijlstra, MD/PhD (1) · Hassan Omar, MD (1) · Jesper N Bech, Ph.D., M.D. (1) · Jesus M Luevano, MD, MS (1) · Joshua D Bundy, PhD, MPH (1)
PMID 18940881, PMID 19727904, PMID 21046483, PMID 21194419, PMID 21849262, PMID 22773591, PMID 25190615, PMID 26856215, PMID 27927683, PMID 28495809, PMID 31986288, PMID 33764198, PMID 33870711, PMID 35609996, PMID 37043520, PMID 38513060, PMID 40779318
2019 (1), P20GM109036 (1), R01AR052322 (1), R01HL079352 (1), R01HL181150 (1)