6 completed, 2 not yet recruiting, 2 recruiting, 2 terminated. 8 Not applicable, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Not yet recruiting 2, Recruiting 2, Unknown 1 |
| Early Phase 1 | 1 | Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Cognitive Symptoms: new trials by email Literature Review of Cognitive Symptoms trials Research Report on Cognitive Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation) - Aging, Depression | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 69 | 2026-12-01 | 2026-10-21 |
| Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults Cranberry juice, Placebo juice - Stress Response, Mental Stress | Not applicable | Recruiting | University of Florida | 84 | 2026-08-01 | 2026-06-30 |
| PQQ for Cognitive and Negative Symptoms Pyrroloquinoline quinone (PQQ), placebo (dietary fiber) - Schizophrenia, Cognitive Symptoms | Not applicable | Not yet recruiting | Tianjin Anding Hospital | 70 | 2026-02-15 | 2026-02-10 |
| Cognitive Rehabilitation for Victims of War and Related Traumas With Traumatic Brain Injury and Cognitive Impairment A Trauma-informed, Paraprofessional Delivered Virtual Cognitive Rehabilitation Program - TBI (Traumatic Brain Injury), Cognitive Symptoms | Not applicable | Recruiting | Massachusetts General Hospital | 50 | 2025-10-15 | 2026-07-09 |
| Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms Written information about potential chemotherapy-related cognitive symptoms without self-affirmation, Written information about potential chemotherapy-related cognitive symptoms with self-affirmation - Breast Cancer, Cognitive Symptoms | Not applicable | Completed | Radboud University Medical Center | 148 | 2014-03-20 | 2021-03-24 |
| Chemotherapy-Induced Cognitive Impairment Cognitive Symptoms | Completed | Jay F. Piccirillo, MD | 28 | 2012-04-01 | 2013-02-26 | |
| COMO: Cognition Study With HIV+ Patients (CTNPT 015) Change in antiretrovirals - HIV - Human Immunodeficiency Virus, Cognitive Symptoms | Early Phase 1 | Terminated | Marie-Josée Brouillette | 19 | 2011-06-01 | 2016-03-16 |
| Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI) Cognitive Intervention, Educational intervention - Traumatic Brain Injury, Cognitive Symptoms | Not applicable | Completed | VA Office of Research and Development | 77 | 2011-03-01 | 2026-04-15 |
| Study of Cognitive Inhibition Disorders in Depressed Older Suicide Attempters Suicide, Attempted, Cognitive Symptoms | Unknown | University Hospital, Angers | 40 | 2010-12-01 | 2011-04-11 | |
| Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment Computer-based Cognitive Training - Breast Cancer, Cognitive Symptoms | Phase 1 | Completed | Posit Science Corporation | 50 | 2006-10-01 | 2008-06-24 |
| Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS) Stroke, Cognitive Symptoms | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 363 | 2006-09-09 | 2017-07-02 | |
| Cognitive Remediation in Supported Employment at Human Service Center (HSC) Computerized cognitive training program - Vocational Rehabilitation, Schizophrenia | Not applicable | Unknown | Human Service Center, Illinois | 50 | 2005-07-01 | 2007-11-02 |
| Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People vitamin B12 supplementation, vitamin B12 + folic acid combined supplementation - Cognitive Decline, Cognitive Symptoms | Not applicable | Completed | Wageningen University | 165 | 2003-05-01 | 2005-06-24 |
| Efficacy and Safety of Rivastigmine in Patients With Mild Cognitive Impairment Rivastigmine - Cognitive Symptoms | Phase 3 | Terminated | Novartis | 24 | 2003-01-01 | 2007-12-17 |
Neurobehavioral Manifestations (14) · Cognitive Dysfunction (6) · Breast Neoplasms (3) · Brain Injuries, Traumatic (2) · Schizophrenia (2) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Anxiety Disorders (1) · Chemotherapy-Related Cognitive Impairment (1) · Dementia (1) · Depression (1) · Fractures, Stress (1) · Memory Disorders (1) · Mental Disorders (1) · Motor Activity (1)
Nervous System Diseases (14) · Neurologic Manifestations (14) · Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (14) · Mental Disorders (7) · Cognition Disorders (6) · Neurocognitive Disorders (6) · Brain Diseases (4) · Central Nervous System Diseases (4) · Behavior (3) · Behavioral Symptoms (3) · Breast Diseases (3) · Neoplasms (3) · Neoplasms by Site (3) · Skin Diseases (3)
Anti-Retroviral Agents (1) · Dietary Fiber (1) · Early Intervention, Educational (1) · PQQ Cofactor (1) · Rivastigmine (1) · Transcranial Direct Current Stimulation (1) · Vitamin B 12 (1)
Human Service Center, Illinois (1) · Jay F. Piccirillo, MD (1) · Marie-Josée Brouillette (1) · Massachusetts General Hospital (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Novartis (1) · Posit Science Corporation (1) · Radboud University Medical Center (1) · Tianjin Anding Hospital (1) · University Hospital, Angers (1) · University of Florida (1) · VA Office of Research and Development (1) · Vanderbilt University Medical Center (1) · Wageningen University (1)
United States (8) · Canada (1) · France (1) · Netherlands (1)
David Loveland, Ph.D. (1) · Enny Das, PhD (1) · Gabe S Sonke, PhD, MD (1) · Henry W Mahncke, PhD (1) · Jay F. Piccirillo, MD (1) · Lewei Gu, PhD (1) · Sanne B Schagen, PhD (1) · Stephane Richard-Devantoy, Mr. (1) · Yelena Bogdanova, PhD PhD (1)
PMID 21733483, PMID 25678046, PMID 26164549, PMID 26709580, PMID 35491320
K23NS128164 (1)