77 completed, 15 unknown, 10 recruiting, 6 active not recruiting. 84 Not applicable, 19 Phase 2, 14 Phase 1, 2 Early Phase 1, 1 Phase 3.
Follow this drug Literature Review of Dietary Fiber trials Research Report on Dietary Fiber
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 80 | 2027-02-15 | 2026-10-06 |
| Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis Fiber, Placebo - Endometriosis, Microbiome Dysbiosis | Not applicable | Not yet recruiting | LOAM Science | 140 | 2026-10-01 | 2026-10-20 |
| Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma. Dried chicory roots, Placebo - Melanoma (Skin) Stage IV, Melanoma (Skin Cancer) | Phase 2 | Recruiting | Radboud University Medical Center | 70 | 2026-07-31 | 2026-07-27 |
| An Open Label Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on GI Health and Related Health Outcomes A ready-to-mix beverage containing protein, fiber, and electrolytes - Health, Wellness | Not applicable | Completed | PepsiCo Global R&D | 133 | 2026-05-04 | 2026-08-27 |
| PQQ for Cognitive and Negative Symptoms Pyrroloquinoline quinone (PQQ), placebo (dietary fiber) - Schizophrenia, Cognitive Symptoms | Not applicable | Not yet recruiting | Tianjin Anding Hospital | 70 | 2026-02-15 | 2026-02-10 |
| The Effects of a Probiotic Food Supplement in Hyperuricaemia Placebo (no active ingredient), Probiotics, Probiotics plus fibre - Hyperuricemia With or Without Gout | Not applicable | Recruiting | Örebro University, Sweden | 99 | 2025-12-16 | 2026-03-27 |
| This Study Aims to Evaluate the Safety and Efficacy of Fiber Supplementation on Constipation in Neurologically Impaired Children Using Rectal Wall Thickness Measurement by Ultrasound. Psyllium Husk, Fiber - Constipation, Neurologically Impaired | Not applicable | Active not recruiting | Ain Shams University | 60 | 2025-11-10 | 2026-08-03 |
| A Prospective Multicenter Study of the Effects of Plant-based Diets on Gut Microbiome and Derived Metabolites in Patients Affected by Smoldering Multiple Myeloma diet rich in fiber - Smoldering Multiple Myeloma (SMM) | Not applicable | Recruiting | Ciceri Fabio | 62 | 2025-10-31 | 2026-04-03 |
| The Effects of a Dialysis-Specific Formula Rich in Branched-Chain Amino Acids, Omega-3, and Dietary Fiber on Nutritional Status BOSCOGEN 18% Protein ONS: Energy 480 kcal, Protein 21.6 g, BCAA 6000 mg, Omega-3 fatty acid 1.8 g, fiber 5 g, Fresubin dialysis ONS (200 ml): Energy 300 kcal, Protein 20 g, BCAA - mg, Omega-3 fatty acid - g, fiber 0.2 g - ESRD (End-Stage Renal Disease), Dialysis | Not applicable | Not yet recruiting | Buddhist Tzu Chi General Hospital | 100 | 2025-07-01 | 2025-07-11 |
| A Randomized, Double-blind Clinical Trial on the Efficacy of a Dietary Formulation Containing Medium-chain Triglycerides (MCT) and Fiber in Patients With Psoriatic Arthritis MCTs and fiber, Placebo powder - Psoriatic Arthritis (PsA) | Not applicable | Completed | Dr. Schär AG / SPA | 72 | 2025-05-16 | 2026-04-20 |
| Effect of Fiber Supplementation on the Need for Medication With Gestational Diabetes Fiber - Gestational Diabetes Mellitus (GDM) | Not applicable | Recruiting | Eastern Virginia Medical School | 110 | 2025-02-24 | 2025-03-10 |
| CMTS4520 for Chronic Diarrhoea in Adults CMTS4520 (dietary fiber and probiotics), Placebo - Diarrhoea | Phase 1 / Phase 2 | Active not recruiting | The Second Hospital of Nanjing Medical University | 100 | 2025-02-20 | 2025-11-18 |
| Evaluation of the Efficacy and Tolerability of an Exclusion Diet in Patients With Juvenile Idiopathic Arthritis complete, polymeric formula, fiber, lactose and gluten free - Juvenile Idiopathic Arthritis (JIA) | Not applicable | Recruiting | Meyer Children's Hospital IRCCS | 20 | 2024-12-12 | 2025-03-13 |
| Satiety and Alcohol Challenge Dietary Fiber + Green Tea Extract, Alcohol, Aspartame Placebo Supplement - Alcohol Drinking | Not applicable | Completed | University of North Carolina, Chapel Hill | 64 | 2024-09-03 | 2025-12-05 |
| Effects of Goji vs. Fiber on Macular Degeneration Goji berry, Fiber - Age-Related Macular Degeneration | Not applicable | Recruiting | University of California, Davis | 60 | 2024-04-29 | 2026-07-17 |
| Fiber Tolerance Study Fiber - Gastrointestinal Tolerance of Dietary Fiber | Early Phase 1 | Completed | Nutricia Research | 43 | 2023-10-04 | 2024-02-06 |
| Bioavailability Study of Hemp Phenolics Low dose dietary fiber, High dose dietary fiber - Bioavailability, Metabolites | Not applicable | Unknown | Brightseed | 10 | 2023-09-15 | 2023-10-24 |
| Persea Americana for Total Health (PATH)-2 Avocado, Oil + Fiber, Average American Diet - Overweight and Obesity | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 45 | 2023-07-11 | 2023-10-13 |
| Fiber's Utilization for Energy and Life Fiber, Control - Diet Habit | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 19 | 2023-05-13 | 2023-12-06 |
| Impact of Dietary Fiber Supplementation on Colonic Microbiome Dietary Fiber, Proctoscopy or anoscopy with Biopsy, Colonoscopy - Benign Colorectal Neoplasm, Non-Neoplastic Anal Disorder | Not applicable | Recruiting | OHSU Knight Cancer Institute | 120 | 2023-04-01 | 2026-01-15 |
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Metabolic Syndrome (9) · Obesity (8) · Inflammation (7) · Insulin Resistance (5) · Overweight (5) · Diabetes Mellitus, Type 2 (4) · Arthritis, Psoriatic (3) · Arthritis, Rheumatoid (3) · Constipation (3) · Diarrhea (3) · Renal Insufficiency, Chronic (3) · Schizophrenia (3) · Autoimmune Diseases (2) · Body Weight (2) · Bone Diseases, Metabolic (2)
Unity Health Toronto (7) · Ingredion Incorporated (4) · Duquesne University (3) · KU Leuven (3) · PepsiCo Global R&D (3) · Stanford University (3) · University of California, Davis (3) · University of Copenhagen (3) · University of Minnesota (3) · Fred Hutchinson Cancer Center (2) · Fugeia NV (2) · Tufts University (2) · University at Buffalo (2) · University of Illinois at Urbana-Champaign (2) · University of Southern Denmark (2)
United States (48) · Canada (7) · Belgium (6) · China (6) · Denmark (6) · United Kingdom (5) · Italy (4) · Netherlands (4) · Brazil (2) · France (2) · Israel (2) · Russia (2) · Sweden (2) · Australia (1) · Austria (1)
Joanne Slavin, PhD (4) · Kevin Maki, PhD (3) · Vladimir Vuksan, PhD (3) · Vibeke Andersen, Prof (2) · Warren Bishop, MD (2) · Willem Broekaert, Ph.D. (2) · Alessandra C Gasior, DO (1) · Alexandra Jenkins, PhD (1) · Alice H Lichtenstein, D.Sc. (1) · Alison L Gibbs, PhD (1) · Alyssa Lebel, MD (1) · Amy Devitt-Maicher, PhD (1) · Andreas Duma, MSc (1) · Andreas FH Pfeiffer, Prof. (1) · Angela M Zivkovic, PhD (1)
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2025 (1), R01DK073321 (1), R21CA245456 (1)