2 terminated, 1 active not recruiting, 1 completed, 1 enrolling by invitation. 2 Early Phase 1, 2 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 2 | Terminated 2 |
| Not applicable | 2 | Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Enrolling by invitation 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study Basal tear collection for the analysis of metabo-lipidomic profiles and concentrations of protein biomarkers (Tau, phosphorylated Tau, Aβ 1-40, and Aβ 1-42), Collection of a blood sample (5 mL) for blood biomarkers analysis - Alzheimer Disease | Not applicable | Recruiting | University Hospital, Tours | 90 | 2025-07-09 | 2025-10-07 |
| Biomarkers Associated With Postoperative Cognitive Dysfunction Intraoperative electroencephalography recording, Neurofilament light chain measurement, Tau protein measurement - Delirium, Postoperative Cognitive Dysfunction | Active not recruiting | University of Oxford | 45 | 2023-01-05 | 2025-06-22 | |
| Metabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent Training Taurine and Exercise (Tau+Ex), Placebo and Exercise (PL+Ex), Taurine (Tau) - Sarcopenic Obesity | Not applicable | Unknown | University of Sao Paulo | 60 | 2022-07-01 | 2022-06-29 |
| Tau Imaging of Chronic Traumatic Encephalopathy [F18]-T807, [F18]-Florbetapir, MRI/MRS - Chronic Traumatic Encephalopathy | Phase 2 | Completed | Brigham and Women's Hospital | 30 | 2015-01-01 | 2018-05-17 |
| A Phase 0, Open Label, Multi-center Exploratory and Safety Study of [F-18]T807 [F18] T807 - Alzheimers Disease, AD | Early Phase 1 | Terminated | Avid Radiopharmaceuticals | 11 | 2012-07-01 | 2013-07-19 |
| A Phase 0, Open Label, Multi-Center, Exploratory and Safety Study of [F-18]T808 [F18] T808 - Alzheimers Disease | Early Phase 1 | Terminated | Avid Radiopharmaceuticals | 12 | 2012-07-01 | 2013-07-19 |
| Imaging of Brain Amyloid Plaques in the Aging Population Pittsburgh Compound B (C-11 PiB), F-18 FDG, Tau (18-F-AV-1451) - Alzheimer's Disease, Dementia With Lewy Bodies | Phase 4 | Enrolling by invitation | Mayo Clinic | 8000 | 2008-04-01 | 2026-06-23 |
Alzheimer Disease (4) · Frontotemporal Dementia (2) · Charcot-Marie-Tooth disease, Type 1F (1) · Chronic Traumatic Encephalopathy (1) · Cognitive Dysfunction (1) · Delirium (1) · Dementia (1) · Dementia, Vascular (1) · Lacerations (1) · Lewy Body Disease (1) · Pick Disease of the Brain (1) · Plaque, Amyloid (1) · Postoperative Cognitive Complications (1)
Avid Radiopharmaceuticals (2) · Brigham and Women's Hospital (1) · Mayo Clinic (1) · University Hospital, Tours (1) · University of Oxford (1) · University of Sao Paulo (1)
United States (4) · France (1) · United Kingdom (1)
Ellen C de Freitas, Ph.D. (1) · Martha E. Shenton, Ph.D. (1) · Martyn Ezra (1) · Val Lowe, M.D. (1)
R01AG011378 (1), U01AG006786 (1)