16 completed, 8 unknown, 5 recruiting, 3 not yet recruiting. 15 Not applicable, 4 Phase 4, 2 Early Phase 1, 1 Phase 1.
Follow Chronic Postoperative Pain: new trials by email Literature Review of Chronic Postoperative Pain trials Research Report on Chronic Postoperative Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL) Cognitive-behavioral therapy - Chronic Postsurgical Pain, Chronic Post-surgical Pain | Not applicable | Not yet recruiting | University Rovira i Virgili | 125 | 2026-11-01 | 2026-10-13 |
| Comparison of Two Postoperative Care Strategies After Breast Surgery Patient Education, Paracetamol, Dexketoprofen - Postoperative Pain, Pain Management | Not applicable | Recruiting | Moumtzidou Maria Aikaterini | 108 | 2026-10-19 | 2026-10-20 |
| Parasternal Intercostal Nerve Block and Chronic Pain After Cardiac Surgery Ultrasound-Guided Parasternal Intercostal Nerve Block, Bupivacaine 0.25% - Chronic Postoperative Pain, Chronic Post-Sternotomy Pain | Not applicable | Not yet recruiting | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | 132 | 2026-09-28 | 2026-09-30 |
| Cardiac Surgery, the Incidence and Impact of Chronic postOperative Pain: a Survey Chronic Postoperative Pain, Cardiac Surgery | Recruiting | Universitaire Ziekenhuizen KU Leuven | 1000 | 2026-06-01 | 2026-06-11 | |
| Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery Group B (Buprenorphine), Group O (Oxycodone) - Acute Postoperative Pain, Chronic Postoperative Pain | Phase 4 | Recruiting | Medical University of Silesia | 200 | 2026-03-18 | 2026-09-25 |
| Benefit on Chronic Pain of Early Screening and Management of Patients With Persistent Postoperative Pain at 3 Months Early management of postoperative pain at 3 months detected using sms - Chronic Postoperative Pain | Not applicable | Not yet recruiting | Fondation Hôpital Saint-Joseph | 2052 | 2025-11-01 | 2025-09-08 |
| Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery Intravenous Analgesia, Thoracic Epidural Analgesia (TEA), Erector Spinae Plane Block (ESPB) - Chronic Postoperative Pain, Open Heart Surgery | Recruiting | Karadeniz Technical University | 90 | 2025-02-15 | 2025-12-02 | |
| Placebo Effect In Spinal Cord Electrical Stimulation for Pain Spinal cord stimulation - Chronic Postoperative Pain | Not applicable | Recruiting | Sahlgrenska University Hospital | 50 | 2024-11-15 | 2025-12-02 |
| Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol - Chronic Postoperative Pain | Not applicable | Unknown | National Cancer Institute, Egypt | 51 | 2024-07-01 | 2024-06-28 |
| PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery Dexamethasone Palmitate, Dexamethasone Sodium Phosphate - Chronic Postoperative Pain | Not applicable | Completed | Xijing Hospital | 562 | 2023-07-11 | 2026-10-14 |
| A Comparative Effect of Echogenic Needle for Nerve Block on Acute and Chronic Postoperative Pain Echogenic nerve block needle, Non-echogenic nerve block needle - Chronic Postoperative Pain | Not applicable | Unknown | The Second Affiliated Hospital of Chongqing Medical University | 1000 | 2023-06-12 | 2024-08-14 |
| Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain Ilioinguinal nerve block - Hernia, Inguinal, Chronic Postoperative Pain | Terminated | The Cleveland Clinic | 10 | 2022-04-20 | 2024-04-05 | |
| Pain Control Following Total Hip Arthroplasty Bupivacaine Hydrochloride 0.25% Injection Solution_#2, EPINEPHrine 1:200,000 / Prilocaine HCl 4 % 1.8 ML Cartridge, Bupivacaine Hydrochloride 0.5% Injection Solution_#2 - Chronic Postoperative Pain | Phase 1 | Completed | St. Mary's Research Center, Canada | 240 | 2021-11-04 | 2024-08-16 |
| The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection thoracic interlaminar epidural injection - Chronic Postoperative Pain, Chest Pain | Not applicable | Completed | Ankara University | 100 | 2021-08-15 | 2024-07-18 |
| Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared) - Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain | Not applicable | Withdrawn | Stanford University | 2021-06-25 | 2022-10-20 | |
| Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital Surgery - Chronic Postoperative Pain, Pediatric ALL | Unknown | Guillermo Ceniza Bordallo | 260 | 2020-12-15 | 2021-08-13 | |
| Help With Early Detection of Postoperative Neuropathic Pain Using SMS After Ambulatory Surgery SMS in the early detection of postoperative neuropathic pain - Chronic Postoperative Pain | Not applicable | Completed | Fondation Hôpital Saint-Joseph | 306 | 2020-12-09 | 2022-11-01 |
| Postoperative Painful Chronicization After Knee Replacement Surgery : Exploratory Study of BDNF's Kinetics blood test - Total Knee Arthroplasty, Chronic Postoperative Pain | Not applicable | Completed | University Hospital, Montpellier | 200 | 2020-12-04 | 2024-06-26 |
| Persistent Postoperative Pain After Major Emergency Abdominal Surgery Chronic Postoperative Pain | Unknown | Zealand University Hospital | 110 | 2020-06-04 | 2020-09-09 | |
| Effect of Intraoperative Dexmedetomidine on Postoperative Pain in Elderly Patients Undergoing Major Abdominal Surgery: a Secondary Analysis Based on Prospective Data Chronic Postoperative Pain | Completed | Chinese PLA General Hospital | 2754 | 2020-04-01 | 2026-08-04 |
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Pain, Postoperative (35) · Chronic Pain (5) · Pain (4) · Agnosia (2) · Acute Pain (1) · Back Pain (1) · Bronchiolitis Obliterans Syndrome (1) · Chest Pain (1) · Headache (1) · Hernia, Inguinal (1) · Knee Injuries (1) · Neuralgia (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Wounds and Injuries (1)
Neurologic Manifestations (35) · Pathologic Processes (35) · Pathological Conditions, Signs and Symptoms (35) · Postoperative Complications (35) · Signs and Symptoms (35) · Pain (31) · Immune System Diseases (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Graft vs Host Disease (1)
Acetaminophen (2) · Oxycodone (2) · Pregabalin (2) · Thoracotomy (2) · Analgesia (1) · Analgesics (1) · Anesthesia, Epidural (1) · Bupivacaine (1) · Buprenorphine (1) · Cognitive Behavioral Therapy (1) · Dexmedetomidine (1) · Drug Delivery Systems (1) · Epinephrine (1) · Fentanyl (1) · Hematologic Tests (1)
Aydin Adnan Menderes University (2) · Fondation Hôpital Saint-Joseph (2) · Ankara University (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Chinese PLA General Hospital (1) · European Society of Anaesthesiology (1) · Fundacion IMIM (1) · Guillermo Ceniza Bordallo (1) · Imperial College Healthcare NHS Trust (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Istanbul University (1) · Karadeniz Technical University (1) · Medical University of Lublin (1) · Medical University of Silesia (1) · Moumtzidou Maria Aikaterini (1)
Spain (6) · Turkey (Türkiye) (5) · China (4) · France (4) · Belgium (2) · Canada (2) · Greece (2) · Poland (2) · United Kingdom (2) · United States (2) · Denmark (1) · Egypt (1) · Germany (1) · Ireland (1) · Italy (1)
Alparslan Turan, Associate Prof (1) · Alparslan Turan, Associate Professor (1) · Andrea Rigamonti, MD (1) · Aykut Soyder, Assistant Professor (1) · Ayse Ilksen Egilmez, Specialist Doctor (1) · Betul Kozanhan, Specialist Doctor (1) · Chong Lei, MD&phD (1) · Daniel I. Sessler, Professor and Ch (1) · Dominique Fletcher, MD (1) · Dr. Anthony Albers, MDCM, FRCSC (1) · Einar Ottestad (1) · Emilia Vassi (1) · Erino A. Rendina, Professor (1)
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