6 completed, 3 recruiting, 2 unknown, 1 available. 5 Not applicable, 4 Phase 2, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 4 | Recruiting 2, Completed 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Chronic Fatigue: new trials by email Literature Review of Chronic Fatigue trials Research Report on Chronic Fatigue
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial) Modafinil, Placebo - Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Chronic Fatigue | Phase 2 / Phase 3 | Recruiting | Radboud University Medical Center | 60 | 2026-08-03 | 2026-09-14 |
| ME/CFS Brain Fog: Cognitive Rehabilitation Trial Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package - ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis | Not applicable | Recruiting | University of Alabama at Birmingham | 30 | 2026-06-23 | 2026-08-14 |
| Chrono-behavioral Therapy for Chronic Fatigue in Cancer Chronotherapy, Control - Chronic Fatigue, Cancer Survivors | Not applicable | Not yet recruiting | Aarhus University Hospital | 200 | 2025-04-01 | 2025-03-14 |
| The Effect of the Human Regenerator Jet Device on the Quality of Life of Adult Individuals [HR-QoL] Cold Atmospheric Plasma, Atmospheric Air - Chronic Stress, Chronic Fatigue | Not applicable | Completed | University of Athens | 40 | 2024-07-09 | 2026-01-27 |
| Ca-Mg Butyrate in Gulf War Illness Cal-Mag Butyrate, Placebo - Gulf War Illness, Chronic Fatigue | Phase 2 | Recruiting | VA Office of Research and Development | 120 | 2024-01-15 | 2026-10-19 |
| The Role of Dysfunctional Schemas and Acceptance Regarding Chronic Fatigue in Oncology Patients After Treatment not appicable - Chronic Fatigue | Completed | Zuyderland Medisch Centrum | 118 | 2023-01-17 | 2025-08-28 | |
| Coenzyme Q10 Phase III Trial in Gulf War Illness Ubiquinol, Placebo - Gulf War Illness, Chronic Fatigue | Phase 3 | Completed | VA Office of Research and Development | 100 | 2017-07-24 | 2023-02-15 |
| Iron Supplementation in Inflammatory Bowel Disease (IBD) Patients With Chronic Fatigue Ferric carboxymaltose, Placebo - Chronic Fatigue, Inflammatory Bowel Disease | Phase 2 | Unknown | Istituto Clinico Humanitas | 36 | 2014-10-01 | 2015-09-10 |
| Fatigue Reduction Diet Social Cognitive Theory - Chronic Fatigue | Not applicable | Completed | University of Michigan | 30 | 2013-11-01 | 2017-02-06 |
| High-dose Ascorbic Acid Intravenous Injection Decreases Mitochondrial DNA Damage in Chronic Fatigue Patients: Randomized-controlled Study ascorbic acid 10g/20ml, Normal Saline 150ml - Chronic Fatigue | Phase 4 | Unknown | Yonsei University | 60 | 2013-08-01 | 2013-08-20 |
| Acupressure for Persistent Cancer Related Fatigue Relaxation Acupressure, Stimulating Acupressure - Chronic Fatigue, Breast Cancer | Phase 2 / Phase 3 | Completed | University of Michigan | 288 | 2011-04-01 | 2015-08-06 |
| A Pilot Study of Amygdala Retraining Program in Patients With Chronic Fatigue Syndrome, Chronic Fatigue and Fibromyalgia Amygdala Retraining Program - Chronic Fatigue Syndrome, Chronic Fatigue | Not applicable | Completed | Mayo Clinic | 57 | 2009-10-01 | 2012-05-03 |
| Expanded Access Use of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Chronic Fatigue of Post-COVID Condition REGENECYTE® - Post-COVID-19 Condition, Post-COVID Condition | Available | StemCyte, Inc. | 2026-03-23 |
Fatigue (3) · Chronic Pain (2) · Cognitive Dysfunction (2) · Colitis, Ulcerative (2) · Fatigue Syndrome, Chronic (2) · Inflammatory Bowel Diseases (2) · Post-Acute COVID-19 Syndrome (2) · Breast Neoplasms (1) · Cognition Disorders (1) · Colitis (1) · Crohn Disease (1) · Dementia (1) · Fibromyalgia (1) · Inflammation (1) · Mental Disorders (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (7) · Chronic Disease (4) · Disease Attributes (4) · Pathologic Processes (4) · Neurocognitive Disorders (3) · COVID-19 (2) · Cognition Disorders (2) · Colonic Diseases (2) · Coronaviridae Infections (2) · Coronavirus Infections (2) · Digestive System Diseases (2) · Encephalomyelitis (2) · Gastroenteritis (2) · Gastrointestinal Diseases (2)
Saline Solution (2) · Ascorbic Acid (1) · Chronotherapy (1) · Modafinil (1) · coenzyme Q10 (1) · ferric carboxymaltose (1) · ubiquinol (1)
University of Michigan (2) · VA Office of Research and Development (2) · Aarhus University Hospital (1) · Istituto Clinico Humanitas (1) · Mayo Clinic (1) · Radboud University Medical Center (1) · StemCyte, Inc. (1) · University of Alabama at Birmingham (1) · University of Athens (1) · Yonsei University (1) · Zuyderland Medisch Centrum (1)
United States (7) · Netherlands (2) · Denmark (1) · Greece (1) · Italy (1) · South Korea (1)
Ali Amidi, PhD (1) · Ann Vincent, MD (1) · Eumorphia Remboutsika, PhD (1) · George P Chrousos, MD, PhD (1) · Gitendra Uswatte, PhD (1) · Lisa M Wu, PhD (1) · Marjolijn Duijvestein, PhD, MD (1) · Nancy G Klimas, BS MD (1) · Saurabh Chatterjee, PhD (1) · Suzanna M Zick, ND, MPH (1) · Suzanna M Zick, Nd, MPH (1)
PMID 22385563, PMID 27388752, PMID 27913933
I01CX002372 (1), R01CA151445 (1)