12 completed, 3 unknown, 2 recruiting, 1 not yet recruiting. 8 Phase 2, 7 Not applicable, 4 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 6, Recruiting 1, Unknown 1 |
| Not applicable | 7 | Completed 4, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 3 | 4 | Completed 3, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow ubiquinol: new trials by email Literature Review of ubiquinol trials Research Report on ubiquinol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Ubiquinol and Ubiquinone on Vascular Function in Healthy Adults With Borderline High LDL-Cholesterol Ubiquinol, Ubiquinone, Placebo - Borderline High LDL-cholesterol | Not applicable | Not yet recruiting | SF Research Institute, Inc. | 120 | 2026-10-17 | 2026-10-19 |
| A Study on Ubiquinol on Fatigue and Muscle Strength in Healthy Adults Taking GLP-1 Agonists Ubiquinol 100 MG Oral Capsule, Placebo - Obesity & Overweight, GLP - 1 | Not applicable | Recruiting | StudySetGo | 90 | 2026-09-01 | 2026-10-19 |
| Ubiquinone vs. Ubiquinol Supplementation Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule - IVF | Phase 2 | Recruiting | Trio Fertility | 90 | 2025-01-23 | 2025-04-10 |
| Comparing the Effects of Commercially Available Dietary Supplements on CoQ10 Concentrations Ubiquinol + geranylgeraniol, Geranylgeraniol, Ubiquinol - Wellness, Health | Phase 2 / Phase 3 | Completed | OvationLab | 150 | 2024-10-12 | 2026-03-04 |
| Coenzyme Q10 and Chemotherapeutic Toxicity in Breast Cancer Patients Placebo, Coenzyme Q10 200mg twice daily - Breast Cancer, Chemotherapeutic Toxicity | Phase 2 | Completed | Damanhour University | 40 | 2024-08-01 | 2025-12-26 |
| Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome ubiquinol (reduced coenzyme Q10), mountain spa rehabilitation, 2x14 ml of peripheral blood collected in a tube with anticoagulant - COVID-19 Respiratory Infection | Not applicable | Completed | Comenius University | 51 | 2021-05-01 | 2022-01-20 |
| Exercise, Creatine and Coenzyme Q10 for Childhood Myositis creatine monohydrate, ubiquinol, glucose tablet - Myositis, Juvenile | Not applicable | Completed | The Hospital for Sick Children | 15 | 2021-04-06 | 2026-04-28 |
| Clinical and Biochemical Assessment of the Effect of Topical Use of Coenzyme Q10 Versus Topical Corticosteroid in Management of Symptomatic Oral Lichen Planus: Randomized Controlled Clinical Trial Co-Enzyme Q10 mucoadhesive tablets - Oral Lichen Planus | Phase 1 | Unknown | Cairo University | 34 | 2019-10-01 | 2019-09-17 |
| Efficacy of Coenzyme Q10 Supplementation on Multi-Organ Dysfunction in Severely Burned Patients CoQ10, Placebo - Multiple Organ Failure | Phase 3 | Withdrawn | American Burn Association | 2018-07-01 | 2023-07-20 | |
| Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain Meal replacement shake, Multivitamin and mineral capsules, Fish oil with sesame lignans and olive extract softgel - Body Weight Changes | Not applicable | Completed | Supplement Formulators, Inc. | 23 | 2017-11-14 | 2018-04-17 |
| Coenzyme Q10 Phase III Trial in Gulf War Illness Ubiquinol, Placebo - Gulf War Illness, Chronic Fatigue | Phase 3 | Completed | VA Office of Research and Development | 100 | 2017-07-24 | 2023-02-15 |
| Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction ubiquinol, Placebo - Heart Failure | Phase 2 | Unknown | Hadassah Medical Organization | 60 | 2016-07-01 | 2016-05-20 |
| Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest Ubiquinol, Ensure - Cardiac Arrest | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 48 | 2016-03-01 | 2021-02-15 |
| The Effect of Coenzyme Q10 on Hearing and Tinnitus Characteristics of Chronic Tinnitus Patients Q10, placebo - Tinnitus | Not applicable | Unknown | University Hospital, Antwerp | 2014-11-01 | 2016-04-18 | |
| Influence of a Short Term Supplementation With Ubiquinol on Diverse Aspects Related to the Physical Activity Ubiquinol, Control - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Universidad de Granada | 100 | 2013-04-01 | 2013-09-12 |
| Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS ubiquinol, placebo, statin - Myopathy, HMG COA Reductase Inhibitor Adverse Reaction | Not applicable | Completed | Beth Israel Deaconess Medical Center | 22 | 2012-10-01 | 2017-04-17 |
| Ubiquinol (Reduced COQ10) for Patients With Sepsis Ubiquinol, Placebo - Sepsis | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 38 | 2012-10-01 | 2017-04-24 |
| Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers Ubiquinol, Placebo - Parkinson Disease | Phase 2 | Completed | Weill Medical College of Cornell University | 11 | 2012-02-28 | 2017-05-23 |
| Bioavailability of Ubiquinol in Huntington Disease ubiquinol - Huntington Disease | Phase 1 | Completed | University of Rochester | 6 | 2009-09-01 | 2016-05-27 |
Inflammation (2) · Body Weight Changes (1) · Breast Neoplasms (1) · Chronic Pain (1) · Cognitive Dysfunction (1) · Dementia (1) · Dermatomyositis (1) · Heart Arrest (1) · Heart Failure (1) · Huntington Disease (1) · Hypercholesterolemia (1) · Lichen Planus, Oral (1) · Mental Disorders (1) · Motor Activity (1) · Multiple Organ Failure (1)
Beth Israel Deaconess Medical Center (3) · American Burn Association (1) · Cairo University (1) · Comenius University (1) · Damanhour University (1) · Hadassah Medical Organization (1) · OvationLab (1) · SF Research Institute, Inc. (1) · StudySetGo (1) · Supplement Formulators, Inc. (1) · The Hospital for Sick Children (1) · Trio Fertility (1) · Universidad de Granada (1) · University Hospital, Antwerp (1) · University of Rochester (1)
United States (9) · Canada (2) · Belgium (1) · Egypt (1) · Slovakia (1) · Spain (1) · United Kingdom (1)
Ahmed Ashour, PhD (1) · Amira B Kassem, PhD (1) · Brian Feldman, MD, MSc (1) · Claire Henchcliffe, MD DPhil (1) · David Leibowitz, MD (1) · Gehad Hassoub, Bachelor (1) · Herb Phelan, MD (1) · Jim S Wu, MD (1) · Julio J Ochoa, Ph.D. (1) · Karl Kieburtz, MD (1) · Michael Donnino, MD (1) · Michael W Donnino, MD (1) · Nancy G Klimas, BS MD (1) · Noha Ahmed El Bassiouny, PhD (1) · Steven Joyal, M.D. (1)
PMID 23638291, PMID 24012996, PMID 26130237, PMID 27993601, PMID 29128354, PMID 31475544, PMID 31986264, PMID 32052466, PMID 32087334, PMID 32541352, PMID 33164536, PMID 33171276, PMID 33364571, PMID 33510633, PMID 33512717, PMID 34273080, PMID 34582480, PMID 34826125, PMID 36339707, PMID 37243171, PMID 37480004, PMID 42401951, PMID 42807157