58 completed, 17 unknown, 9 terminated, 7 withdrawn. 34 Not applicable, 18 Phase 4, 13 Phase 2, 8 Phase 3, 2 Phase 1.
Follow Chronic Bronchitis: new trials by email Literature Review of Chronic Bronchitis trials Research Report on Chronic Bronchitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis Metered cryospray (MCS) - COPD (Chronic Obstructive Pulmonary Disease), Chronic Bronchitis | Not applicable | Not yet recruiting | CSA Medical, Inc. | 10 | 2027-01-02 | 2026-10-05 |
| Clinical Study of the Pulsed Electric Field Ablation System in Chronic Obstructive Pulmonary Disease Pulse electric field ablation system, Sham Procedure - Chronic Bronchitis, COPD (Chronic Obstructive Pulmonary Disease) | Not applicable | Recruiting | Suzhou Hengruihongyuan Medical Technology Co. LTD | 210 | 2025-09-01 | 2025-09-02 |
| Pulmonary Deposition of Ultrasound Rock Salt Aerosol Inhalation Therapy USN before SVN, SVN before USN - COPD, Asthma Bronchiale | Not applicable | Not yet recruiting | Jingen Xia | 26 | 2025-03-31 | 2025-03-24 |
| Effects of Pursed Lip Breathing Technique Versus Stacked Breathing Technique Among Chronic Bronchitis Patients pursed lip, Stacked Breathing - Chronic Bronchitis | Not applicable | Completed | Riphah International University | 34 | 2024-01-05 | 2024-04-19 |
| Comparison Of Blow Bottle Positive Expiratory Pressure (BBPEP) Versus Acapella Among Patient With Chronic Bronchitis blow bottle positive expiratory pressure, acapella - Chronic Bronchitis | Not applicable | Completed | Riphah International University | 36 | 2023-07-20 | 2023-12-27 |
| A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis. Guafenesin tablets - Chronic Bronchitis | Phase 4 | Completed | American Health Research | 82 | 2023-07-17 | 2026-03-20 |
| A Clinical Evaluation of the RheOx Bronchial Rheoplasty System RheOx™ with the RheOx™ Catheter treated in the trial - Chronic Bronchitis, Chronic Obstructive Pulmonary Disease | Not applicable | Completed | Energenx Medical LTD. | 40 | 2023-05-18 | 2026-08-21 |
| Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic Bronchitis Pulse electric field ablation system developed by Zhouling (Shanghai) Medical Appliance Co., Ltd. - Chronic Bronchitis | Not applicable | Unknown | Jiayuan Sun | 15 | 2023-03-10 | 2023-03-16 |
| Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILE thoracic scan Low dose, BLOOD SAMPLE, FECES SAMPLE - Smoking-related Pathology, Atheroma | Not applicable | Unknown | Assistance Publique Hopitaux De Marseille | 160 | 2023-01-23 | 2024-03-18 |
| Resistive Breathing Versus Inspiratory Hold Technique in Patients With Chronic Bronchitis Resistive Breathing Training group, inspiratory hold technique - Chronic Bronchitis | Not applicable | Unknown | Riphah International University | 26 | 2022-09-01 | 2022-09-09 |
| Early Mobilization With and Without Chest Physiotherapy in Chronic Bronchitis Patients. chest physiotherapy and early mobilization, early mobilization - Chronic Bronchitis | Not applicable | Unknown | Riphah International University | 26 | 2022-05-01 | 2022-12-12 |
| Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes E-Cigarette, Financial Incentives - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Phase 2 | Completed | University of Vermont | 21 | 2022-04-28 | 2024-02-08 |
| Evaluation of Immunological, Microbiological and Metabolomic Profiles in COPD COPD, Emphysema | Completed | Medical University of Warsaw | 92 | 2022-03-01 | 2025-02-14 | |
| A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China Diagnostic Test: Sputum DNA methylation analysis, chest CT or pathological examination - Lung Cancer, Small Cell Lung Cancer | Completed | Creative Biosciences (Guangzhou) Co., Ltd. | 1564 | 2022-02-25 | 2025-03-21 | |
| Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-12-01 | 2021-11-02 |
| Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-10-08 | 2021-10-22 |
| Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-10-08 | 2021-10-22 |
| Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng) Zhuli capsule, Placebo, Standard medical treatment - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Phase 4 | Unknown | Zhong Wang | 324 | 2021-07-01 | 2021-06-15 |
| Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis RheOx Bronchial Rheoplasty, Sham Procedure - Chronic Bronchitis | Not applicable | Unknown | Gala Therapeutics, Inc. | 270 | 2021-04-07 | 2023-06-27 |
| A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB) ION-827359, Placebo - Chronic Bronchitis, Chronic Obstructive Pulmonary Disease | Phase 2 | Terminated | Ionis Pharmaceuticals, Inc. | 60 | 2020-12-22 | 2022-12-20 |
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Bronchitis, Chronic (99) · Pulmonary Disease, Chronic Obstructive (74) · Emphysema (35) · Bronchitis (10) · Asthma (6) · Smoking (6) · Lung Diseases (5) · Anxiety Disorders (3) · COVID-19 (3) · Community-Acquired Pneumonia (3) · Depression (3) · Dyspnea (3) · Inflammation (3) · Lung Neoplasms (3) · Pneumonia (3)
Bronchial Diseases (99) · Chronic Disease (99) · Disease Attributes (99) · Infections (99) · Pathologic Processes (99) · Pathological Conditions, Signs and Symptoms (99) · Respiratory Tract Diseases (99) · Lung Diseases, Obstructive (97) · Respiratory Tract Infections (97) · Lung Diseases (94) · Bronchitis (89) · Pulmonary Disease, Chronic Obstructive (25) · Behavior (14) · Hypersensitivity (7) · Immune System Diseases (7)
Azithromycin (5) · Formoterol Fumarate (5) · Moxifloxacin (4) · Acetylcysteine (3) · Salmeterol Xinafoate (3) · Losartan (2) · Roflumilast (2) · Sugars (2) · Tiotropium Bromide (2) · ivacaftor (2) · telithromycin (2) · Albuterol (1) · Amikacin (1) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1)
Gala Therapeutics, Inc. (5) · Imperial College London (5) · CSA Medical, Inc. (4) · Johns Hopkins University (4) · Riphah International University (4) · University of North Carolina, Chapel Hill (4) · Bayer (3) · China National Biotec Group Company Limited (3) · Abbott (2) · AstraZeneca (2) · Karolinska Institutet (2) · Sanofi (2) · Sumitomo Pharma America, Inc. (2) · University of Alabama at Birmingham (2) · University of California, Los Angeles (2)
United States (43) · United Kingdom (14) · China (12) · Canada (7) · Germany (6) · France (5) · Netherlands (5) · Pakistan (5) · Czechia (4) · Spain (4) · Austria (3) · Hungary (3) · Italy (3) · Australia (2) · Belgium (2)
Louise E Donnelly, PhD (4) · William Krimsky, MD (3) · Adam Hloska, M.D. (2) · Hanqing He (2) · Alejandro Cornellas, MD (1) · Arschang Valipour, MD (1) · Ashley G Henderson, MD (1) · Athol Wells, MD (1) · Beth Laube, PhD (1) · Bruce K Rubin, MEng,MD,MBA (1) · Christopher Cooper, MD, PhD (1) · Christopher James, PA (1) · Claudia Onofrei, MD, MSc (1)
PMID 40571054, PMID 28487349, PMID 39615802, PMID 12324669, PMID 15155777, PMID 15229100, PMID 15878486, PMID 16113473, PMID 16334970, PMID 16953188, PMID 17261234, PMID 18274560, PMID 19750190, PMID 19897561, PMID 20580216, PMID 21145201, PMID 21233263, PMID 21471087, PMID 21631367, PMID 21760724, PMID 21809909, PMID 21940765, PMID 22230731, PMID 22292600, PMID 22497533, PMID 22652413, PMID 22772084, PMID 22843558, PMID 23146379, PMID 23172272, PMID 23265285, PMID 23298873, PMID 23420871, PMID 23600492, PMID 24229360, PMID 24264182, PMID 24397870, PMID 24564813, PMID 24604485, PMID 24928812, PMID 24972036, PMID 25442794, PMID 25514500, PMID 25562375, PMID 26082623, PMID 26338015, PMID 26836895, PMID 26962015, PMID 26965288, PMID 27143871
P01HL108808 (1), P50HL084934 (1), P50HL084945 (1), R01HL093081 (1), R01HL133240 (1), R01HL139365 (1), R01HL144718 (1), R03NR009361 (1), R34HL127166 (1), U01HL137880 (1), U24HL141762 (1), U54DA036114 (1)