8 completed, 6 unknown, 2 terminated, 2 withdrawn. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Completed 8, Unknown 6, Terminated 2, Withdrawn 2 |
Follow Chronic Bronchitis: new trials by email Literature Review of Chronic Bronchitis trials Research Report on Chronic Bronchitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis. Guafenesin tablets - Chronic Bronchitis | Phase 4 | Completed | American Health Research | 82 | 2023-07-17 | 2026-03-20 |
| Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-12-01 | 2021-11-02 |
| Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-10-08 | 2021-10-22 |
| Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPD Inactivated COVID-19 vaccine - COVID-19, Chronic Bronchitis | Phase 4 | Unknown | China National Biotec Group Company Limited | 400 | 2021-10-08 | 2021-10-22 |
| Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng) Zhuli capsule, Placebo, Standard medical treatment - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Phase 4 | Unknown | Zhong Wang | 324 | 2021-07-01 | 2021-06-15 |
| VX-770 for the Treatment of Chronic Bronchitis Ivacaftor (VX-770) - Chronic Bronchitis | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2020-01-01 | 2022-02-17 | |
| Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis Losartan 50 mg, Losartan 100 mg - COPD, Chronic Bronchitis | Phase 4 | Terminated | University of Miami | 31 | 2016-03-31 | 2020-08-20 |
| The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis Roflumilast, Placebo - COPD, Chronic Bronchitis | Phase 4 | Completed | Johns Hopkins University | 12 | 2013-03-18 | 2017-07-27 |
| Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography Nebulized arformoterol, Salmeterol - Chronic Obstructive Pulmonary Disease, COPD | Phase 4 | Unknown | University of California, Los Angeles | 20 | 2011-06-01 | 2012-07-20 |
| Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Combined Training (endurance and strength exercises) - Obstructive Chronic Pulmonary Disease, Emphysema | Phase 4 | Unknown | Hospitales Universitarios Virgen del Rocío | 30 | 2011-01-01 | 2011-09-09 |
| Efficacy of Losartan in Preventing Progression of COPD Losartan, Placebo - COPD, Emphysema | Phase 4 | Completed | Johns Hopkins University | 106 | 2008-07-01 | 2017-04-25 |
| Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis Avelox (Moxifloxacin, BAY12-8039), Amoxicillin clavulanic acid - Chronic Bronchitis | Phase 4 | Completed | Bayer | 1372 | 2008-03-01 | 2014-12-01 |
| Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT) formoterol fumarate - Chronic Obstructive Pulmonary Disease, COPD | Phase 4 | Withdrawn | University of California, Los Angeles | 2008-03-01 | 2016-08-04 | |
| Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients Formoterol plus Placebo (Tiotropium), Formoterol plus Tiotropium - Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis | Phase 4 | Completed | Federal University of São Paulo | 33 | 2007-11-01 | 2010-01-20 |
| KEYS: Study Comparing Clinical Health Outcomes of Telithromycin Versus Azithromycin in Outpatients With Community-acquired Lower Respiratory Tract Infections Telithromycin, Azithromycin - Respiratory Tract Infections, Chronic Bronchitis | Phase 4 | Terminated | Sanofi | 2051 | 2004-10-01 | 2009-08-27 |
| Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation pneumatic vest, placebo pneumatic vest - COPD, Chronic Bronchitis | Phase 4 | Completed | Johns Hopkins University | 50 | 2004-05-01 | 2018-10-19 |
| PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis telithromycin - Chronic Bronchitis | Phase 4 | Completed | Sanofi | 5660 | 2004-01-01 | 2011-06-08 |
| Inhaled Steroid Reduces Systemic Inflammation in COPD inhaled fluticasone 500 mcg b.i.d. - Chronic Obstructive Pulmonary Disease, Emphysema | Phase 4 | Completed | University of British Columbia | 50 | 2002-01-01 | 2010-07-28 |
Bronchitis, Chronic (18) · Pulmonary Disease, Chronic Obstructive (14) · Emphysema (7) · COVID-19 (3) · Smoking (3) · Lung Diseases (2) · Bronchitis (1) · Dyspnea (1) · Inflammation (1) · Pneumonia (1) · Pulmonary Emphysema (1) · Respiratory Tract Infections (1)
Bronchial Diseases (18) · Chronic Disease (18) · Disease Attributes (18) · Infections (18) · Lung Diseases, Obstructive (18) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Respiratory Tract Diseases (18) · Bronchitis (17) · Respiratory Tract Infections (17) · Lung Diseases (16) · Pulmonary Disease, Chronic Obstructive (4) · Behavior (3) · Coronaviridae Infections (3) · Coronavirus Infections (3)
Formoterol Fumarate (3) · Losartan (2) · Sugars (2) · telithromycin (2) · Acetylcysteine (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Azithromycin (1) · Moxifloxacin (1) · Roflumilast (1) · Salmeterol Xinafoate (1) · Tiotropium Bromide (1) · ivacaftor (1)
China National Biotec Group Company Limited (3) · Johns Hopkins University (3) · Sanofi (2) · University of California, Los Angeles (2) · American Health Research (1) · Bayer (1) · Federal University of São Paulo (1) · Hospitales Universitarios Virgen del Rocío (1) · University of Alabama at Birmingham (1) · University of British Columbia (1) · University of Miami (1) · Zhong Wang (1)
United States (9) · China (5) · Canada (3) · Spain (3) · Belgium (2) · Brazil (2) · France (2) · Andorra (1) · Argentina (1) · Australia (1) · Chile (1) · Colombia (1) · Croatia (1) · Czechia (1) · Germany (1)
Hanqing He (2) · Beth Laube, PhD (1) · Donald P Tashkin, M.D. (1) · Eric Kleerup, M.D. (1) · Gilles Perdriset, MD (1) · Gregory B Diette, M.D.,M.H.S (1) · J Alberto Neder, MD, phD (1) · Nadia Hansel, MD MPH (1) · Ortega F Ruiz, Doctor (1) · Paul Man, MD (1) · Phyllis Diener, BS, MT (ASCP) (1) · Rafael Calderon, MD (1) · Robert A. Wise, MD (1) · Selwyn Spangenthal, MD (1)
PMID 15229100, PMID 16113473, PMID 20580216, PMID 21760724, PMID 26082623
P50HL084945 (1), R01HL133240 (1), R01HL139365 (1)