11 completed, 2 terminated. 13 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 11, Terminated 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Chronic Bronchitis: new trials by email Literature Review of Chronic Bronchitis trials Research Report on Chronic Bronchitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes E-Cigarette, Financial Incentives - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Phase 2 | Completed | University of Vermont | 21 | 2022-04-28 | 2024-02-08 |
| A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB) ION-827359, Placebo - Chronic Bronchitis, Chronic Obstructive Pulmonary Disease | Phase 2 | Terminated | Ionis Pharmaceuticals, Inc. | 60 | 2020-12-22 | 2022-12-20 |
| A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis Tozorakimab, Placebo - Chronic Obstructive Pulmonary Disease (COPD), Chronic Bronchitis | Phase 2 | Completed | AstraZeneca | 137 | 2020-12-14 | 2025-02-27 |
| The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor Ivacaftor 150 MG, Placebo - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Phase 2 | Completed | University of Alabama at Birmingham | 40 | 2017-03-16 | 2024-12-12 |
| Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters Ropivacaine, placebo - Scheduled Cardiac Surgery, Sternotomy | Phase 2 | Completed | University Hospital, Clermont-Ferrand | 120 | 2013-04-27 | 2026-08-06 |
| Safety/Tolerability and Efficacy of YHD001 in Patients With Acute and Chronic Bronchitis YHD001 dose level 1, YHD001 dose level 2, Pelargonium sidoides extract - Acute Bronchitis, Chronic Bronchitis | Phase 2 | Completed | Yuhan Corporation | 118 | 2011-09-01 | 2013-09-26 |
| PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Prochymal™, Placebo - Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema | Phase 2 | Completed | Mesoblast, Inc. | 62 | 2008-03-20 | 2026-03-11 |
| Helium:Oxygen Noninvasive Positive Pressure Ventilation in Patients Exposed to Sulfur Mustard helium:oxygen mixture - Bronchiolitis, Chronic Bronchitis | Phase 2 / Phase 3 | Completed | Baqiyatallah Medical Sciences University | 23 | 2007-04-01 | 2008-03-25 |
| Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis azithromycin and fluticasone, fluticasone and azithromycin - Bronchiectasis, Pulmonary Disease | Phase 2 | Terminated | University of Milan | 210 | 2006-09-01 | 2009-03-13 |
| Real-Time Support for Exercise Persistence in COPD Coached exercise persistence intervention, Self-Monitored exercise persistence intervention - Pulmonary Disease, Chronic Obstructive, COPD | Phase 1 / Phase 2 | Completed | University of Washington | 17 | 2006-05-01 | 2009-12-07 |
| Phase 2 Study - Erdosteine in Patients With CB/COPD Erdosteine - Chronic Bronchitis, Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Adams Respiratory Therapeutics | 400 | 2006-03-01 | 2007-12-06 |
| Yoga for Treating Shortness of Breath in Chronic Obstructive Pulmonary Disease (COPD) yoga - Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive | Phase 1 / Phase 2 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 36 | 2003-01-01 | 2006-08-18 |
| Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic Bronchitis Oral N-acetycystein (NAC) - Chronic Bronchitis | Phase 2 | Completed | Wake Forest University | 240 | 1997-01-01 | 2017-11-06 |
Bronchitis, Chronic (13) · Pulmonary Disease, Chronic Obstructive (8) · Emphysema (2) · Pulmonary Emphysema (2) · Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome (1) · Bronchiectasis (1) · Bronchiolitis (1) · Bronchitis (1) · Inflammation (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Motor Activity (1) · Obesity (1) · Pain, Postoperative (1) · Vaping (1)
Bronchial Diseases (13) · Chronic Disease (13) · Disease Attributes (13) · Infections (13) · Pathologic Processes (13) · Pathological Conditions, Signs and Symptoms (13) · Respiratory Tract Diseases (13) · Respiratory Tract Infections (13) · Bronchitis (12) · Lung Diseases (12) · Lung Diseases, Obstructive (12) · Pulmonary Disease, Chronic Obstructive (5) · Behavior (2) · Asthma (1) · Body Weight (1)
Azithromycin (1) · Electronic Nicotine Delivery Systems (1) · Fluticasone (1) · Ropivacaine (1) · Yoga (1) · erdosteine (1) · ivacaftor (1) · remestemcel-l (1)
Adams Respiratory Therapeutics (1) · AstraZeneca (1) · Baqiyatallah Medical Sciences University (1) · Ionis Pharmaceuticals, Inc. (1) · Mesoblast, Inc. (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · University Hospital, Clermont-Ferrand (1) · University of Alabama at Birmingham (1) · University of Milan (1) · University of Vermont (1) · University of Washington (1) · Wake Forest University (1) · Yuhan Corporation (1)
United States (8) · Czechia (2) · Germany (2) · Hungary (2) · United Kingdom (2) · Australia (1) · Canada (1) · Denmark (1) · France (1) · Iran (1) · Israel (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Poland (1)
Bruce K Rubin, MEng,MD,MBA (1) · Christopher James, PA (1) · Diann E Gaalema, PhD (1) · Francesco Blasi, MD (1) · Helmut Albrecht, MD (1) · Huong Q. Nguyen, PhD (1) · Vedat Eljezi (1) · Virginia Carrieri-Kohlman, RN, DNSc (1) · Young Kyoon Kim, M.D., Ph.D. (1)
PMID 19750190, PMID 22292600, PMID 22772084, PMID 23172272, PMID 27977439, PMID 33964910, PMID 39316773
R03NR009361 (1), R34HL127166 (1), U54DA036114 (1)