73 completed. 73 Phase 1, 23 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 73 | Completed 73 |
| Phase 2 | 23 | Completed 23 |
Follow Child Development Disorders, Pervasive: new trials by email Literature Review of Child Development Disorders, Pervasive trials Research Report on Child Development Disorders, Pervasive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With Autism Spectrum Disorder Lumateperone 10.5 mg capsule, Lumateperone 21 mg capsule, Lumateperone 5 mg ODT - Autism Spectrum Disorder | Phase 1 | Completed | Intra-Cellular Therapies, Inc. | 33 | 2024-05-10 | 2026-07-24 |
| Use of MRI and cTBS for Catatonia in Autism Continuous Theta Burst in Transcranial Magnetic Stimulation - Autism Spectrum Disorder, Catatonia | Phase 1 | Completed | Vanderbilt University Medical Center | 26 | 2023-08-23 | 2025-12-31 |
| ASC - Autism Study Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®) - Autism Spectrum Disorder, Gastrointestinal Dysfunction | Phase 1 | Completed | Cell to Cure ApS | 10 | 2023-06-09 | 2024-09-26 |
| hCT-MSC Infusion in Adults With Autism Spectrum Disorder hCT-MSC - Autism Spectrum Disorder, Autism | Phase 1 | Completed | Joanne Kurtzberg, MD | 8 | 2022-01-24 | 2024-07-23 |
| 28-Day Daily-dose Crossover Study of the Safety and Tolerability of SB-121 (Lactobacillus Reuteri With Sephadex® and Maltose) in Subjects, Ages 15 to 45 Years, Diagnosed With Autistic Disorder SB-121, Placebo - Autistic Disorder | Phase 1 | Completed | Scioto Biosciences, Inc. | 15 | 2021-08-02 | 2024-03-25 |
| Safety and Efficacy of Oral Full-Spectrum Medicinal Cannabis Plant Extract in Children With Autism Spectrum Disorder. FEN164 - Autism Spectrum Disorder | Phase 1 / Phase 2 | Completed | Fenix Innovation Group | 18 | 2021-04-01 | 2026-09-08 |
| Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder hCT-MSC infusion - Autism Spectrum Disorder | Phase 1 | Completed | Duke University | 12 | 2021-02-24 | 2025-02-24 |
| Safety, Tolerability and Pharmacokinetics Study of STP1 in a Subgroup of Patients With Autism Spectrum Disorder (ASD) STP1, Placebo - Autism Spectrum Disorder | Phase 1 | Completed | Stalicla SA | 12 | 2020-12-07 | 2024-11-08 |
| Electrical Brain Stimulation and Pharmacological Treatments in Autism Spectrum Disorder RisperiDONE 1 MG/ML, transcranial direct current stimulation, Placebo - Autism Spectrum Disorder | Phase 1 | Completed | The National Brain Mapping Laboratory (NBML) | 45 | 2020-08-15 | 2023-11-07 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants RO6953958, Placebo, Midazolam - Autistic Disorder, Autism Spectrum Disorder | Phase 1 | Completed | Hoffmann-La Roche | 88 | 2020-07-15 | 2024-07-10 |
| Cariprazine Pediatric ASD PK Study Cariprazine - Autism Spectrum Disorder | Phase 1 | Completed | AbbVie | 24 | 2020-06-26 | 2022-04-12 |
| Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders Bioactive Factors, Produced by M2 Type Macrophages (M2-BFs). - Language Delay, Language; Developmental Disorder, Expressive | Phase 1 / Phase 2 | Completed | Russian Academy of Medical Sciences | 14 | 2020-02-01 | 2022-05-02 |
| A Study to Investigate the Effect of Esomeprazole and the Effect of Food on the Pharmacokinetics of Balovaptan in Healthy Volunteers Balovaptan, Esomeprazole - Autism Spectrum Disorder | Phase 1 | Completed | Hoffmann-La Roche | 16 | 2019-11-19 | 2021-03-16 |
| UCB Stem Cells for Autism Spectrum Disorders umbilical cord blood mononuclear stem cells - Autism Spectrum Disorder | Phase 1 | Completed | St. Petersburg Bekhterev Research Psychoneurological Institute | 30 | 2019-11-04 | 2021-08-04 |
| A Proof-of-Concept Study of Minocycline in Autism Minocycline, Placebos - Autism Spectrum Disorder, Autism | Phase 1 | Completed | Children's Hospital Medical Center, Cincinnati | 53 | 2019-04-19 | 2020-12-08 |
| Umbilical Cord Blood vs Personalized Treatments for Improving Autistic Disorder Intranasal oxytocin, Autologous umbilical cord blood - Autistic Spectrum Disorder | Phase 1 | Completed | Fundatia Bio-Forum | 35 | 2019-01-17 | 2023-08-23 |
| Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children intranasal oxytocin, oral probiotics, oral placebo - Autism Spectrum Disorder | Phase 1 | Completed | Massachusetts General Hospital | 35 | 2018-12-01 | 2020-03-04 |
| Allogenic Cord Blood Transfusion in Patients With Autism ASD CB-MNC injection., Standard therapy. - Autism Spectrum Disorder, Autism | Phase 1 / Phase 2 | Completed | State-Financed Health Facility "Samara Regional Medical Center Dinasty" | 20 | 2018-10-12 | 2020-11-19 |
| A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD) No Intervention - Autism Spectrum Disorder | Phase 1 | Completed | Hoffmann-La Roche | 144 | 2018-08-13 | 2022-06-21 |
| Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513 RO7017773, [11C] Ro15-4513 - Autism Spectrum Disorder | Phase 1 | Completed | Hoffmann-La Roche | 6 | 2018-04-24 | 2019-09-30 |
Showing 20 of 73. Sign in to see all of them.
Autistic Disorder (47) · Autism Spectrum Disorder (41) · Asperger Syndrome (5) · Attention Deficit Disorder with Hyperactivity (3) · Fragile X Syndrome (3) · Intellectual Disability (3) · Anxiety Disorders (2) · Cerebral Palsy (2) · Cognitive Dysfunction (2) · Developmental Disabilities (2) · Down Syndrome (2) · Language (2) · Neurodevelopmental Disorders (2) · Schizophrenia (2)
Mental Disorders (72) · Neurodevelopmental Disorders (71) · Autism Spectrum Disorder (32) · Nervous System Diseases (13) · Neurobehavioral Manifestations (9) · Neurologic Manifestations (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Genetic Diseases, Inborn (8) · Behavior (7) · Congenital Abnormalities (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Chromosome Disorders (6) · Abnormalities, Multiple (5)
Oxytocin (5) · Cognitive Behavioral Therapy (3) · Risperidone (3) · Hyperbaric Oxygenation (2) · Probiotics (2) · Sodium Chloride (2) · (6-chloro-1-(2-(dimethylamino)ethyl)indol-3-yl)-spiro(1H-isobenzofuran-3,4'-piperidine)-1'-yl-methanone (1) · Acamprosate (1) · Buspirone (1) · Cholesterol (1) · Citalopram (1) · Donepezil (1) · Esomeprazole (1) · Everolimus (1) · Fluorine-18 (1)
Children's Hospital Medical Center, Cincinnati (5) · Hoffmann-La Roche (5) · Duke University (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Joanne Kurtzberg, MD (2) · National Institute of Mental Health (NIMH) (2) · University of North Carolina, Chapel Hill (2) · AbbVie (1) · Alliant International University (1) · Anagnostou, Evdokia, M.D. (1) · Arizona State University (1) · Boston Children's Hospital (1) · Cell to Cure ApS (1) · Children's Treatment Network (1) · Chugani, Diane C. (1)
United States (52) · United Kingdom (4) · Russia (3) · Brazil (2) · Canada (2) · Norway (2) · Australia (1) · China (1) · Denmark (1) · France (1) · Iran (1) · Netherlands (1) · Panama (1) · Romania (1) · Thailand (1)
Joanne Kurtzberg, MD (4) · Jessica Sun, MD (3) · Craig Erickson, MD (2) · Geraldine Dawson, PhD (2) · Alan S Lewis, MD, PhD (1) · Alexander A Ostanin, MD, PhD (1) · Alexander Vinks, Pharm.D., Ph.D. (1) · Allen Song, PhD (1) · Ana Carina Tamanaha, Student (1) · Andrew W Zimmerman, MD (1) · Andrew Wakefield, MD (1) · Anett Kaale, PhD student (1)
PMID 37811711, PMID 16554123, PMID 19948568, PMID 20145986, PMID 20680427, PMID 21883204, PMID 22537359, PMID 22588377, PMID 23106988, PMID 23978163, PMID 24439092, PMID 24472253, PMID 25313065, PMID 25526831, PMID 26631428, PMID 27711048, PMID 28122648, PMID 30230399, PMID 30967657, PMID 32082606, PMID 32242086, PMID 32616759, PMID 33087514, PMID 33473111, PMID 34034808, PMID 34693989, PMID 35594551, PMID 35941573, PMID 36997569, PMID 39062003
2019 (2), 2014 (1), K01MH079945 (1), K23MH081285 (1), R01HD095158 (1), R34HD065274 (1), U54HD079124 (1), U54MH066397 (1), U54MH066399 (1), U54NS092090 (1)