19 completed, 5 recruiting, 4 active not recruiting, 4 terminated. 38 Phase 2, 7 Phase 1, 1 Phase 3.
Follow Cecal Diseases: new trials by email Literature Review of Cecal Diseases trials Research Report on Cecal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE) Shared decision-making, amoxicillin-clavulanate, Appendectomy - Acute Appendicitis | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 560 | 2026-10-01 | 2026-10-05 |
| Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC) Modified early post-operative intraperitoneal chemotherapy (mEPIC) - Peritoneal Carcinomatosis, Appendiceal Neoplasms | Phase 2 | Recruiting | Ciusss de L'Est de l'Île de Montréal | 25 | 2026-05-01 | 2026-05-14 |
| A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors VS-7375, Cetuximab, Carboplatin + Pemetrexed + Pembrolizumab - Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | Verastem, Inc. | 616 | 2025-06-24 | 2026-11-10 |
| Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA) Piperacillin/tazobactam, Normal saline, CefTRIAXone Injection - Appendicitis Perforated | Phase 2 | Completed | McMaster Children's Hospital | 16 | 2024-09-09 | 2026-07-07 |
| Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors Elironrasib, Daraxonrasib - Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer | Phase 1 / Phase 2 | Recruiting | Revolution Medicines, Inc. | 534 | 2023-11-14 | 2026-09-22 |
| Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma Surufatinib, Sintilimab, Capecitabine - Adenocarcinoma of Small Intestine, Appendix Carcinoma | Phase 2 | Recruiting | Sun Yat-sen University | 36 | 2023-02-01 | 2025-12-17 |
| Antibiotic Instillation in Appendicitis Ceftriaxone, Intra-peritoneal Fluid Aspiration - Complicated Appendicitis, Acute Appendicitis | Phase 2 | Completed | Johns Hopkins All Children's Hospital | 190 | 2023-01-05 | 2025-03-13 |
| Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis Paclitaxel, Nilotinib, ECG - Gynecologic Cancer, Gynecologic Neoplasms | Phase 2 | Completed | National Cancer Institute (NCI) | 21 | 2022-10-13 | 2026-06-25 |
| JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation JAB-21822, Cetuximab - Advanced Colorectal Cancer, Small Intestinal Cancer | Phase 1 / Phase 2 | Active not recruiting | Allist Pharmaceuticals, Inc. | 48 | 2022-02-17 | 2026-03-16 |
| Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC Mitomycin C, flat dose 40 mg, Mitomycin C, weight-based dose 12.5 mg/m2 - Peritoneal Carcinomatosis | Phase 2 | Recruiting | Prakash Pandalai | 100 | 2021-06-04 | 2026-04-01 |
| Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer Acupuncture Therapy, Acupressure Therapy, Oral Cryotherapy - Appendix Carcinoma, Colon Carcinoma | Phase 2 | Completed | University of Washington | 78 | 2021-06-01 | 2026-01-21 |
| Laparoscopically Guided Rectus Sheath Block in Pediatric Appendicitis Rectus Sheath Block with 0.25% bupivicaine with 1:200 000 epinephrine, Local Anesthetic Infiltration with 0.25% bupivicaine with 1:200 000 epinephrine - Appendicitis Acute | Phase 2 | Completed | University of Alberta | 42 | 2021-05-28 | 2024-03-12 |
| Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors CBX-12 - Solid Tumor, Adult, Epithelial Ovarian Cancer | Phase 1 / Phase 2 | Completed | Cybrexa Therapeutics | 69 | 2021-05-03 | 2026-08-20 |
| Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis antibiotic rinse with suction, suction only - Perforated Appendicitis | Phase 2 | Active not recruiting | Prisma Health-Upstate | 200 | 2019-07-25 | 2026-01-27 |
| The Role of Contrast Enhanced Ultrasound in Appendicitis Sulfur hexafluoride lipid-type A microspheres - Acute Appendicitis | Phase 2 | Completed | Children's Mercy Hospital Kansas City | 37 | 2019-01-04 | 2023-09-08 |
| Non-operative Treatment of Acute Non-perforated Appendicitis Meronem and flagyl, Appendectomy - Acute Appendicitis | Phase 2 / Phase 3 | Completed | King Edward Medical University | 180 | 2018-09-01 | 2021-02-18 |
| Intraperitoneal Administration of Fosfomycin, Metronidazole and Molgramostim Versus Intravenous Antibiotics for Perforated Appendicitis Combination of fosfomycin, metronidazole and rhGM-CSF (administered together intraperitoneally) and three days of antibiotics p.o., Standard antibiotics intravenously - Appendicitis Perforated | Phase 2 | Completed | Herlev Hospital | 13 | 2018-02-14 | 2018-10-16 |
| LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma nintedanib - Appendix Cancer | Phase 2 | Terminated | Wake Forest University Health Sciences | 5 | 2017-11-10 | 2022-08-09 |
| PIPAC for Peritoneal Metastases of Colorectal Cancer repetitive ePIPAC-OX - Colorectal Neoplasms, Peritoneal Neoplasms | Phase 2 | Completed | Koen Rovers | 20 | 2017-10-01 | 2019-10-15 |
| A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies ONCOS-102, Durvalumab, Cyclophosphamide - Colorectal Cancer, Ovarian Cancer | Phase 1 / Phase 2 | Completed | Ludwig Institute for Cancer Research | 67 | 2017-09-07 | 2022-12-22 |
Showing 20 of 38. Sign in to see all of them.
Appendiceal Neoplasms (22) · Appendicitis (16) · Colorectal Neoplasms (13) · Colonic Neoplasms (7) · Rectal Neoplasms (7) · Pancreatic Neoplasms (6) · Peritoneal Neoplasms (6) · Stomach Neoplasms (6) · Esophageal Neoplasms (4) · Carcinoma, Hepatocellular (3) · Carcinoma, Non-Small-Cell Lung (3) · Gastrointestinal Neoplasms (3) · Neoplasm Metastasis (3) · Neoplasms (3) · Ovarian Neoplasms (3)
Digestive System Diseases (38) · Gastrointestinal Diseases (38) · Intestinal Diseases (38) · Digestive System Neoplasms (22) · Cecal Neoplasms (21) · Intestinal Neoplasms (21) · Neoplasms by Site (21) · Gastrointestinal Neoplasms (19) · Neoplasms (19) · Colonic Diseases (16) · Gastroenteritis (16) · Infections (16) · Intraabdominal Infections (16) · Rectal Diseases (16)
Mitomycin (6) · Metronidazole (5) · Appendectomy (3) · Hyperthermic Intraperitoneal Chemotherapy (3) · Ceftriaxone (2) · Cetuximab (2) · Leucovorin (2) · Melphalan (2) · Oxaliplatin (2) · Ropivacaine (2) · Saline Solution (2) · 130-nm albumin-bound paclitaxel (1) · Acupressure (1) · Acupuncture Therapy (1) · Amoxicillin (1)
Wake Forest University Health Sciences (3) · Gustave Roussy, Cancer Campus, Grand Paris (2) · Herlev Hospital (2) · Albert Einstein College of Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Allist Pharmaceuticals, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Children's Mercy Hospital Kansas City (1) · Ciusss de L'Est de l'Île de Montréal (1) · Cybrexa Therapeutics (1) · Delcath Systems Inc. (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Göteborg University (1) · Helsinki University Central Hospital (1) · Johns Hopkins All Children's Hospital (1)
United States (22) · France (5) · Canada (4) · China (3) · Denmark (2) · Netherlands (2) · Spain (2) · Australia (1) · Finland (1) · Germany (1) · Italy (1) · Pakistan (1) · Puerto Rico (1) · Sweden (1)
Dominique Elias, MD (2) · Andrew M Blakely, M.D. (1) · Armando Sardi, M.D. (1) · Djamila Boerma, MD, PhD (1) · Edward Levine (1) · Garrett Nash, MD, MPH (1) · Ignace de Hingh, MD, PhD (1) · Jimmy J Hwang, MD (1) · John McAuliffe, M.D. (1) · Kent Lundholm (1) · KuoJen Tsao, MD (1) · Marybeth Hughes, MD (1) · Mazin Al-kasspooles, MD (1) · Michael H Livingston, MD, MSc (1)
PMID 11427329, PMID 19358184, PMID 21958060, PMID 25581711, PMID 27437029, PMID 30366723, PMID 31040341, PMID 31352425, PMID 31567357, PMID 32432123, PMID 32572849, PMID 33544279, PMID 34757489, PMID 36410913, PMID 37993560, PMID 40056080, PMID 41202087, PMID 41344351, PMID 42384131
2017 (1), 2025 (1), P30CA015704 (1)