130-nm albumin-bound paclitaxel: Clinical Trials

794 trials of 130-nm albumin-bound paclitaxel, newest first

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264 completed, 156 recruiting, 96 unknown, 86 terminated. 506 Phase 2, 268 Phase 1, 124 Phase 3, 11 Not applicable, 7 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 2506Completed 147, Recruiting 102, Unknown 73, Not yet recruiting 59, Terminated 51, Active not recruiting 43, Withdrawn 26, Enrolling by invitation 4, Suspended 1
Phase 1268Completed 114, Terminated 44, Recruiting 40, Active not recruiting 24, Unknown 18, Withdrawn 14, Not yet recruiting 11, Suspended 3
Phase 3124Completed 37, Recruiting 36, Active not recruiting 20, Not yet recruiting 10, Terminated 10, Unknown 8, Withdrawn 2, Suspended 1
Not applicable11Recruiting 3, Unknown 3, Active not recruiting 2, Completed 2, Not yet recruiting 1
Phase 47Unknown 4, Completed 2, Not yet recruiting 1
Early Phase 15Completed 2, Withdrawn 2, Terminated 1

Follow this drug Literature Review of 130-nm albumin-bound paclitaxel trials Research Report on 130-nm albumin-bound paclitaxel

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC
certepetide, nab-paclitaxel, gemcitabine - Pancreas Cancer, Pancreatic Carcinoma
Phase 1 / Phase 2WithdrawnLisata Therapeutics, Inc.2030-01-012025-06-06
SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial
Biospecimen Collection, Computed Tomography, Electronic Health Record Review - Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma
Phase 2Not yet recruitingNorthwestern University1252027-02-032026-08-06
Evaluation of the Efficacy and Safety of Neoadjuvant Therapy in Patients With Surgically Resectable Pancreatic Adenocarcinoma.
GnP, FOLFIRINOX - Pancreatic Adenocarcinoma Resectable, Non Metastatic
Phase 2Not yet recruitingGustave Roussy, Cancer Campus, Grand Paris422027-01-012026-09-15
Zanzalintinib and Pembrolizumab in First-Line Maintenance for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)
Carboplatin, Paclitaxel, Nab-paclitaxel - Squamous Non-Small Cell Lung Cancer (NSCLC)
Phase 2Not yet recruitingExelixis602026-12-152026-09-29
Trial of First-line Gemcitabine and Nab-paclitaxel With or Without L-glutamine in Advanced Pancreatic Cancer
Gemcitabine (1000 mg/m2), Nab-paclitaxel, L-glutamine - Pancreatic Cancer
Phase 2Not yet recruitingJun Gong, MD2002026-12-012026-10-08
PD-1 Blockade Alone Versus in Combination With Chemotherapy as First Line Therapy in Females With Advanced NSCLC & PD-L1 Expression ≥50%
Pembrolizumab, Carboplatin (AUC 5), Cisplatin (75 mg/m²) - Non-Small Cell Lung Cancer
Phase 3Not yet recruitingGerman Cancer Research Center4062026-11-302026-10-16
A Study to Learn the Safety and Efficacy of HLX37 in Combination With Chemotherapy for First-line Treatment in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Investigational drug: HLX37 dose1, IV, Q3W, PEMBROLIZUMAB (alone or when added to a regimen above), Carboplatin (Investigator discretion) - NSCLC (Advanced Non-small Cell Lung Cancer)
Phase 2 / Phase 3Not yet recruitingShanghai Henlius Biotech14382026-11-302026-10-08
MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC
PD-1 inhibitor, Carboplatin, Nab-paclitaxel - Non-Small Cell Lung Cancer (NSCLC)
Phase 2Not yet recruitingPeking University People's Hospital1002026-11-012026-10-21
Safety and Efficacy of Radiotherapy Combined With Immunochemotherapy in Pre-treated SCLC Patients With Liver Metastases
Immunotherapy, Chemotherapy (Etoposide, Nab-paclitaxel, Irinotecan, or Lurbinectedin), low-dose radiation - Lung Cancer (SCLC)
Phase 2Not yet recruitingSichuan University302026-10-312026-05-05
A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002)
MK-2010, Pembrolizumab, 5-Fluorouracil - Malignant Neoplam, Advanced Solid Tumors
Phase 2Not yet recruitingMerck Sharp & Dohme LLC4802026-10-272026-10-08
Antibody-Drug Conjugate Plus Immunotherapy Versus Immunotherapy Plus Chemotherapy for Extensive Transurethrally Unresectable Very-High-Risk Non-Muscle-Invasive Bladder Cancer
Disitamab Vedotin and Toripalimab, Toripalimab and Nab-Paclitaxel - Bladder (Urothelial, Transitional Cell) Cancer, Antibody-drug Conjugates
Phase 2Not yet recruitingTianjin Medical University Second Hospital1502026-10-202026-10-16
A Phase 3 Study of Manganese-primed Immunochemotherapy in Patients With Advanced Ovarian Cancer
Manganese Chloride, Nab-paclitaxel, Platinum chemotherapy - Ovarian Cancer
Phase 3RecruitingChinese PLA General Hospital1202026-10-122026-09-16
Rimegepant-Sensitized Neoadjuvant Chemoimmunotherapy for Oral or Oropharyngeal Squamous Cell Carcinoma
Rimegepant, Tislelizumab, Nab-paclitaxel - Oral Squamous Cell Carcinoma (OSCC), Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Phase 2Not yet recruitingShanghai Zhongshan Hospital2202026-10-012026-09-10
DCE-MRI for Neoadjuvant Treatment Assessment in Patients With Borderline Resectable Pancreatic Cancer
Biospecimen Collection, Computed Tomography, Dynamic Contrast-Enhanced Magnetic Resonance Imaging - Borderline Resectable Pancreatic Ductal Adenocarcinoma
Phase 1 / Phase 2RecruitingOhio State University Comprehensive Cancer Center502026-10-012026-10-05
Neoadjuvant Sintilimab Plus Chemotherapy for cT2N0M0 Oral Squamous Cell Carcinoma
Sintilimab, Nab-Paclitaxel, Carboplatin - Oral Squamous Cell Carcinoma (OSCC), Head and Neck Squamous Cell Carcinoma
Phase 3Not yet recruitingcaohaotian3002026-10-012026-09-18
Utilizing Standard of Care Induction Chemotherapy Followed by MR-LINAC Radiotherapy and Surgical Exploration to Improve Resectability Rates in Potentially Resectable Locally Advanced Pancreatic Cancer
Induction Chemotherapy - FOLFIRINOX, Induction Chemotherapy - Gemcitabine and Nab-Paclitaxel, MR-LINAC Guided Radiotherapy - Pancreatic Cancer
Phase 2Not yet recruitingAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)202026-10-012026-10-13
Relacorilant and Nab-Paclitaxel in Recurrent or Metastatic Cervical Cancer
Relacorilant, Nab-paclitaxel - Recurrent or Metastatic Cervical Cancer
Phase 2Not yet recruitingARCAGY/ GINECO GROUP632026-10-012026-08-13
GnP Combined With SHR-1701 and Apatinib as First-Line Treatment for Locally Advanced or Metastatic PDAC
SHR-1701, Apatinib, gemcitabine - Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
Phase 1 / Phase 2Not yet recruitingWest China Hospital452026-09-102026-09-03
Node-Sparing Short-Course Radiotherapy (25 Gy/5 Fractions) Combined With Chemoimmunotherapy as Neoadjuvant Treatment for Locally Advanced Esophageal Squamous Cell Carcinoma:A Prospective Single-Arm, Phase II Study
Neoadjuvant SCRT + Camrelizumab + Nab-Paclitaxel/Carboplatin - ESCC
Phase 2RecruitingSixth Affiliated Hospital, Sun Yat-sen University332026-09-102026-09-09
A Study of BL-B01D1 Plus an Anti-PD-1 Antibody Versus Nab-paclitaxel Plus an Anti-PD-1 Antibody in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Express PD-L1 (PANKU-Breast04)
BL-B01D1, PD-1 monoclonal antibody, Nab-paclitaxel - Triple-Negative Breast Cancer (TNBC)
Phase 3RecruitingSichuan Baili Pharmaceutical Co., Ltd.4362026-09-022026-09-30

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Conditions studied

Pancreatic Neoplasms (205)  ·  Breast Neoplasms (112)  ·  Carcinoma, Non-Small-Cell Lung (102)  ·  Triple Negative Breast Neoplasms (68)  ·  Neoplasm Metastasis (49)  ·  Neoplasms (45)  ·  Lung Neoplasms (26)  ·  Squamous Cell Carcinoma of Head and Neck (26)  ·  Esophageal Squamous Cell Carcinoma (21)  ·  Colorectal Neoplasms (19)  ·  Adenocarcinoma (17)  ·  Stomach Neoplasms (17)  ·  Head and Neck Neoplasms (16)  ·  Melanoma (15)  ·  Ovarian Neoplasms (13)

Sponsors

ImmunityBio, Inc. (22)  ·  M.D. Anderson Cancer Center (21)  ·  Merck Sharp & Dohme LLC (21)  ·  Fudan University (20)  ·  Hoffmann-La Roche (17)  ·  Celgene (16)  ·  Tianjin Medical University Cancer Institute and Hospital (13)  ·  Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (11)  ·  AstraZeneca (10)  ·  Bristol-Myers Squibb (10)  ·  National Cancer Institute (NCI) (10)  ·  Chinese PLA General Hospital (9)  ·  Washington University School of Medicine (9)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (8)  ·  Gilead Sciences (8)

Countries

United States (395)  ·  China (263)  ·  Spain (111)  ·  Germany (87)  ·  France (83)  ·  Italy (82)  ·  Australia (74)  ·  South Korea (74)  ·  Canada (67)  ·  United Kingdom (66)  ·  Japan (64)  ·  Taiwan (57)  ·  Belgium (52)  ·  Poland (45)  ·  Brazil (44)

Top investigators

Jared Weiss, MD (6)  ·  Erwei Song, M.D., Ph.D. (3)  ·  Guopei Luo, MD (3)  ·  Peng Zhang, PhD (3)  ·  Ana De Jesus-Acosta, MD (2)

Results publications

PMID 32450725, PMID 34252375, PMID 31401903, PMID 35511917, PMID 37364223, PMID 37499870, PMID 38050737, PMID 12049861, PMID 22547591, PMID 24703985, PMID 24885187, PMID 25476537, PMID 25579459, PMID 25679067, PMID 25845992, PMID 25961845, PMID 26056183, PMID 26201606, PMID 26254683, PMID 26698868, PMID 26808342, PMID 26869049, PMID 27000274, PMID 27244882, PMID 27404453, PMID 27701653, PMID 27840089, PMID 27876675, PMID 28114604, PMID 28179342, PMID 28315068, PMID 28620884, PMID 28701571, PMID 28797458, PMID 28869790, PMID 28918548, PMID 28939558, PMID 29119276, PMID 29158367, PMID 29190925, PMID 29228091, PMID 29232172, PMID 29273007, PMID 29327055, PMID 29346519, PMID 29409469, PMID 29438178, PMID 29441562, PMID 29691300, PMID 29695765

NIH funding

2023 (18), 2016 (12), 2025 (12), 2014 (11), 2017 (8), 2018 (8), 2019 (8), 2015 (7), U10CA180820 (5), P30CA138292 (4), P30CA033572 (3), U10CA180868 (3), U10CA180888 (3), P30CA015083 (2), P30CA015704 (2)