9 completed, 3 unknown, 1 enrolling by invitation, 1 not yet recruiting. 16 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 16 | Completed 9, Unknown 3, Enrolling by invitation 1, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Cardiovascular Abnormalities: new trials by email Literature Review of Cardiovascular Abnormalities trials Research Report on Cardiovascular Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Daratumumab for Familial Cerebral Cavernous Malformations: A Single-Arm Safety and Efficacy Study Daratumumab - Cavernous Malformation, Cerebral | Early Phase 1 | Not yet recruiting | Beijing Tiantan Hospital | 10 | 2025-07-01 | 2025-06-18 |
| The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease Thiamine - Congenital Heart Disease, Thiamine Deficiency | Early Phase 1 | Completed | Universitas Sumatera Utara | 86 | 2024-05-01 | 2026-03-24 |
| Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children The use of a combination of microelements and vitamins against the background of physiotherapy - Respiratory Diseases, Congenital Heart Defects | Early Phase 1 | Enrolling by invitation | Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan | 600 | 2023-11-08 | 2026-09-03 |
| Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study LUX-Dx™ - Univentricular Heart | Early Phase 1 | Completed | Boston Children's Hospital | 10 | 2023-03-15 | 2026-05-19 |
| Effect of Parenteral Alpha-Tocopherol in the Definitive Surgery of Tetralogy of Fallot alpha-Tocopherol, Sterile Water for Injection - Tetralogy of Fallot (TOF), Alpha-tocopherol | Early Phase 1 | Completed | Dr Cipto Mangunkusumo General Hospital | 60 | 2022-05-01 | 2025-09-26 |
| Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients 1.25mg bevacizumab, 2.50mg bevacizumab - End Stage Renal Disease, Hemodialysis Vascular Access Failure | Early Phase 1 | Withdrawn | Mayo Clinic | 2019-08-01 | 2026-06-24 | |
| Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning CT angiography - Arteriovenous Malformations | Early Phase 1 | Completed | University of Texas Southwestern Medical Center | 14 | 2019-07-25 | 2024-10-15 |
| Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension? Sildenafil, Placebo - Patent Foramen Ovale, Intrapulmonary Arteriovenous Anastamosis | Early Phase 1 | Completed | University of Oregon | 82 | 2019-07-01 | 2023-08-14 |
| Pumps for Kids, Infants, and Neonates Surgical placement of the Jarvik 2015 VAD, Surgical Placement of Jarvik 2015 VAD - Pediatric Heart Failure | Early Phase 1 | Unknown | Carelon Research | 7 | 2018-10-22 | 2023-09-21 |
| Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients With Heart Disease Cholate testing - Liver Disease, Cardiovascular Disease | Early Phase 1 | Completed | Northwestern University | 14 | 2015-09-01 | 2018-08-22 |
| Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS Ferumoxytol, Tissue Analysis, Magnetic Resonance Imaging - Brain Injury, Central Nervous System Degenerative Disorder | Early Phase 1 | Completed | Michael Iv | 10 | 2015-06-10 | 2017-08-31 |
| Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study Vemurafenib, serial 124I PET/CT, thyrotropin alpha - Thyroid Carcinoma | Early Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 12 | 2014-05-20 | 2025-06-18 |
| Exercise Capacity and Quality of Life in Patients With PPH Receiving Short Term Oral L-Citrulline Malate L-Citrulline Malate - Idiopathic Pulmonary Arterial Hypertension, Eisenmenger Syndrome | Early Phase 1 | Unknown | Masih Daneshvari Hospital | 25 | 2012-08-01 | 2013-08-12 |
| Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins Simvastatin - Cavernous Angioma, Familial, Cerebral Cavernous Malformations | Early Phase 1 | Terminated | University of New Mexico | 12 | 2012-03-01 | 2024-03-12 |
| Outcomes in Patients and Their Closest Relatives Treated for Congenital Heart Disease With Catheter Based or Surgical Techniques Percutaneous pulmonary valve implantation or open heart surgery - Congenital Heart Defects | Early Phase 1 | Unknown | Oslo University Hospital | 40 | 2011-09-01 | 2012-09-25 |
| Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO) sodium citrate - Heart Defects, Congenital, Respiratory Insufficiency | Early Phase 1 | Completed | Vanderbilt University | 2 | 2010-01-01 | 2015-06-03 |
Heart Defects, Congenital (6) · Hemangioma, Cavernous, Central Nervous System (2) · Arteriovenous Fistula (1) · Arteriovenous Malformations (1) · Brain Injuries (1) · Brain Neoplasms (1) · Bronchitis (1) · Cardiomyopathies (1) · Cardiovascular Diseases (1) · Central Nervous System Infections (1) · Central Nervous System Vascular Malformations (1) · Congenital Abnormalities (1) · Ductus Arteriosus, Patent (1) · Eisenmenger Complex (1) · Familial Primary Pulmonary Hypertension (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Cardiovascular Diseases (15) · Congenital Abnormalities (15) · Heart Diseases (10) · Heart Defects, Congenital (5) · Vascular Diseases (5) · Vascular Malformations (5) · Neoplasms (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Hemic and Lymphatic Diseases (3) · Nervous System Diseases (3) · Nervous System Malformations (3) · Cavernous Sinus Syndromes (2)
Bevacizumab (1) · Ferrosoferric Oxide (1) · Injections (1) · Magnetic Resonance Spectroscopy (1) · Sildenafil Citrate (1) · Simvastatin (1) · Sodium Citrate (1) · Thiamine (1) · Thyrotropin Alfa (1) · Tissue Array Analysis (1) · Vemurafenib (1) · alpha-Tocopherol (1) · daratumumab (1)
Beijing Tiantan Hospital (1) · Boston Children's Hospital (1) · Carelon Research (1) · Dr Cipto Mangunkusumo General Hospital (1) · Masih Daneshvari Hospital (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · Michael Iv (1) · Northwestern University (1) · Oslo University Hospital (1) · Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan (1) · Universitas Sumatera Utara (1) · University of New Mexico (1) · University of Oregon (1) · University of Texas Southwestern Medical Center (1)
United States (8) · Indonesia (2) · China (1) · Iran (1) · Norway (1) · Uzbekistan (1)
Alan L. Ho, MD, PhD (1) · Andrew Lovering, PhD (1) · Blaine Hart, MD (1) · Daniel Ganger, MD (1) · Erik Fosse, Professor/Head of Department (1) · John B Pietsch, MD (1) · Leslie A Morrison, MD (1) · Michael Iv, MD (1) · Putri Amelia (1) · Robert Timmerman, MD (1) · Sanjay Misra, MD (1) · Shokhida T Turdieva, D.Sc. (1) · William T Mahle, MD (1)
U54NS065705 (1)