19 recruiting, 11 completed, 7 unknown, 4 enrolling by invitation. 8 Not applicable, 5 Phase 2, 4 Phase 1.
Follow Arrhythmogenic Right Ventricular Dysplasia: new trials by email Literature Review of Arrhythmogenic Right Ventricular Dysplasia trials Research Report on Arrhythmogenic Right Ventricular Dysplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiac Rehabilitation in Patients With High-Genetic-Risk Arrhythmogenic Cardiomyopathy: The HGEN-CARE-AC Trial Cardiac Rehabilitation Programme - Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Not applicable | Not yet recruiting | Juan Jiménez Jáimez | 70 | 2026-09-01 | 2026-07-20 |
| Treatment Registry of Arrhythmias, Complications and Electrocardiograms in Arrhythmogenic CardioMyopathies Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Ventricular Tachycardia (VT) | Not yet recruiting | Policlinico Casilino ASL RMB | 300 | 2026-07-01 | 2026-07-07 | |
| PKP2-ACM Natural History Study Cardiomyopathies, Heart Diseases | Recruiting | Rocket Pharmaceuticals Inc. | 36 | 2026-05-15 | 2026-10-14 | |
| Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant Arrhythmogenic Cardiomyopathy, PKP2-ACM | Enrolling by invitation | Lexeo Therapeutics | 10 | 2025-08-29 | 2025-11-12 | |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC)) 68Ga-DOTA-SA-FAPI PET/CT - Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 15 | 2025-04-16 | 2026-05-04 |
| Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy Tideglusib, Placebo - Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy | Phase 2 | Recruiting | Hamilton Health Sciences Corporation | 120 | 2025-03-21 | 2026-03-12 |
| AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA CCTAI model - Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM) | Not yet recruiting | Shanghai Zhongshan Hospital | 5000 | 2024-12-30 | 2024-12-27 | |
| Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD Spironolactone, Placebo - Arrhythmogenic Right Ventricular Dysplasia | Phase 2 | Recruiting | Hospices Civils de Lyon | 120 | 2024-12-20 | 2026-02-09 |
| IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy IC14 - Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Left Ventricular Cardiomyopathy | Phase 1 / Phase 2 | Completed | Implicit Bioscience | 1 | 2024-03-29 | 2026-04-22 |
| Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC TN-401 - Arrhythmogenic Right Ventricular Cardiomyopathy | Phase 1 | Recruiting | Tenaya Therapeutics | 15 | 2024-03-26 | 2025-02-06 |
| Gene Therapy for ACM Due to a PKP2 Pathogenic Variant LX2020 - Arrhythmogenic Cardiomyopathy, PKP2-ACM | Phase 1 / Phase 2 | Active not recruiting | Lexeo Therapeutics | 10 | 2024-02-29 | 2025-11-12 |
| A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM Arrhythmogenic Cardiomyopathy, PKP2-ACM | Recruiting | Lexeo Therapeutics | 40 | 2024-01-23 | 2025-05-16 | |
| Low QRS Voltages in Young Healthy Individuals and Athletes Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida) - Sudden Cardiac Death, Sudden Cardiac Arrest | Unknown | Imperial College London | 240 | 2023-10-09 | 2023-10-04 | |
| A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM) RP-A601 - PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) | Phase 1 | Recruiting | Rocket Pharmaceuticals Inc. | 9 | 2023-08-29 | 2026-04-16 |
| Arrhythmogenic Activity During Exercise in ARVC Patients Exercise - Arrhythmogenic Right Ventricular Cardiomyopathy | Not applicable | Recruiting | Swiss Federal Institute of Technology | 120 | 2023-08-01 | 2026-03-24 |
| Cardiovascular Multimodality Imaging Study Non-ischemic Cardiomyopathy, Cardiomyopathies | Recruiting | Montefiore Medical Center | 10000 | 2023-05-01 | 2026-08-10 | |
| Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Arrhythmogenic Right Ventricular Cardiomyopathy | Recruiting | Tenaya Therapeutics | 200 | 2023-01-31 | 2024-11-01 | |
| Athlete's Heart or Arrhythmogenic Right Ventricular Cardiomyopathy: Contribution of Exercise Cardiovascular Magnetic Resonance (CMR) Cardiac exercises and tests - Arrhythmogenic Right Ventricular Cardiomyopathy | Not applicable | Terminated | Rennes University Hospital | 4 | 2023-01-16 | 2026-10-15 |
| Local Inflammation in Arrhythmogenic Right Ventricular Cardiomyopathy Peripheral immunological assessment on venous blood, Immunological assessment carried out on intracardiac material - Arrhythmogenic Right Ventricular Dysplasia | Not applicable | Recruiting | University Hospital, Toulouse | 80 | 2022-02-01 | 2026-06-01 |
Showing 20 of 47. Sign in to see all of them.
Cardiomyopathy, Hypertrophic (15) · Cardiomyopathies (14) · Cardiomyopathy, Dilated (13) · Death, Sudden, Cardiac (12) · Brugada Syndrome (9) · Cardiomyopathy, Restrictive (9) · Long QT Syndrome (8) · Heart Arrest (6) · Heart Failure (6) · Polymorphic Catecholaminergic Ventricular Tachycardia (6) · Arrhythmias, Cardiac (5) · Tachycardia, Ventricular (5) · Cardiovascular Diseases (4) · Heart Diseases (4)
Congenital Abnormalities (47) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (47) · Heart Defects, Congenital (47) · Cardiovascular Abnormalities (46) · Cardiovascular Diseases (43) · Heart Diseases (43) · Cardiomyopathies (33) · Pathological Conditions, Signs and Symptoms (24) · Pathologic Processes (23) · Genetic Diseases, Inborn (21) · Aortic Stenosis, Subvalvular (15) · Aortic Valve Disease (15) · Aortic Valve Stenosis (15) · Cardiac Conduction System Disease (15) · Heart Valve Diseases (15)
Genetic Testing (2) · Echocardiography (1) · Electrocardiography (1) · Equipment and Supplies (1) · Exercise (1) · Flecainide (1) · Hematologic Tests (1) · Spironolactone (1) · Walking (1) · atibuclimab (1) · tideglusib (1)
University of British Columbia (4) · Lexeo Therapeutics (3) · Beijing Institute of Heart, Lung and Blood Vessel Diseases (2) · Rocket Pharmaceuticals Inc. (2) · Tenaya Therapeutics (2) · University Hospital, Toulouse (2) · Assistance Publique - Hôpitaux de Paris (1) · China National Center for Cardiovascular Diseases (1) · German Heart Institute (1) · Göteborg University (1) · Hamilton Health Sciences Corporation (1) · Heidelberg University (1) · Hospices Civils de Lyon (1) · Hospital do Coracao (1) · Imperial College London (1)
United States (16) · France (7) · Canada (6) · Germany (5) · United Kingdom (5) · China (3) · Italy (2) · Sweden (2) · Brazil (1) · India (1) · Netherlands (1) · Switzerland (1) · Turkey (Türkiye) (1)
Andrew D Krahn, MD (2) · Alessandro Nudi, MD (1) · Andreas Barth, MD (1) · Andreas Metzner, MD (1) · Andreas Rillig, MD (1) · Andrew D Krahn, Dr. (1) · Andrew Krahn, MD FRCPC (1) · Angeliki Asimaki (1) · Barry Greenberg, MD (1) · Chenguang Li, MD, PhD (1) · Christina M Spengler, PhD, MD (1) · Cinzia Crescenzi, MD (1) · Felix Berger, MD (1)
PMID 37979797, PMID 16203906, PMID 19597050, PMID 20172911, PMID 20172912, PMID 21816308, PMID 21955300, PMID 22944906, PMID 25896080, PMID 26783233, PMID 27635072, PMID 28600387, PMID 31333075, PMID 33512057, PMID 33960826, PMID 35252369, PMID 37638409, PMID 39048282, PMID 39998828, PMID 40810874, PMID 41732243, PMID 42381624, PMID 42669063
2023 (1), 2025 (1), R01HL128743 (1), R34HL143372 (1), U01HL065594 (1), U01HL065652 (1), U01HL065691 (1)