30 completed, 9 unknown, 8 terminated, 7 recruiting. 27 Not applicable, 14 Phase 2, 6 Phase 4, 5 Phase 1, 4 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis Therapeutic Plasma Exchange, Rituximab, Intravenous immunoglobulin - Idiopathic Pulmonary Fibrosis | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 52 | 2026-12-01 | 2026-10-20 |
| Evaluating DFPP for Microplastic and PFAS Reduction Double-Filtration Plasmapheresis With the IN300 Apheresis Device - Microplastic and Nanoplastic Particle Burden in Peripheral Blood, Double-Filtration Plasmapheresis | Enrolling by invitation | Proxima Health, Inc. | 20 | 2026-06-12 | 2026-07-24 | |
| Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP 2 (PALADIN2) plasmapheresis - Amyotrophic Lateral Sclerosis (ALS), Autoantibody | Not applicable | Recruiting | National Taiwan University Hospital | 20 | 2026-05-19 | 2026-07-24 |
| Observational Study on Immunoadsorption (IA) in Patients With Autoantibody-Positive Post-Infectious ME/CFS IA with TheraSorb ® column (Miltenyi) - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), ME/CFS Following COVID-19 | Recruiting | Charite University, Berlin, Germany | 50 | 2026-03-11 | 2026-04-14 | |
| Immunoadsorption in Autoimmune Long COVID Immunoadsorption, Sham Comparator - Long COVID, Long COVID Syndrome | Phase 2 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 70 | 2026-01-01 | 2026-01-05 |
| Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers Best Practice, Biospecimen Collection, Central Venous Cannula Insertion - Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis and Ureter Urothelial Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 70 | 2025-08-01 | 2026-05-08 |
| Efficacy and Safety of Plasma Adsorption Combined With EVT for AIS-LVO Plasma adsorption, Endovascular Thrombectomy - Acute Ischemic Stroke From Large Vessel Occlusion, Endovascular Thrombectomy | Not applicable | Not yet recruiting | Yi Yang | 100 | 2025-06-30 | 2025-06-29 |
| Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM) Immunoadsorption - Dilated Cardiomyopathy (DCM) | Not applicable | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2025-06-04 | 2025-06-04 |
| A Gene Transfer Therapy to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) Following Therapeutic Plasma Exchange (Plasmapheresis) in Participants With Duchenne Muscular Dystrophy (DMD) and Pre-existing Antibodies to AAVrh74 delandistrogene moxeparvovec, Plasmapheresis - Duchenne Muscular Dystrophy | Phase 1 | Terminated | Sarepta Therapeutics, Inc. | 3 | 2024-09-18 | 2025-09-04 |
| Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS Immunoadsorption - ME/CFS, Post-COVID ME/CFS | Not applicable | Completed | Charite University, Berlin, Germany | 66 | 2023-10-01 | 2026-01-16 |
| Immunoadsorption Study Mainz in Adults With Post-COVID Syndrome Immunoadsorption, Sham-apheresis - Post-COVID-19 Syndrome, Post-COVID Syndrome | Not applicable | Completed | University Medical Center Mainz | 40 | 2023-05-08 | 2025-07-28 |
| Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP Plasmapheresis - Amyotrophic Lateral Sclerosis, Plasmapheresis | Not applicable | Completed | National Taiwan University Hospital | 5 | 2023-05-01 | 2026-07-22 |
| Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Immunoadsorption, Immunoglobulins - CIDP | Phase 2 | Recruiting | University of Ulm | 20 | 2023-05-01 | 2026-05-01 |
| Effect of Plasmapheresis on Clinical Improvement and Biological Parameters of Patients With Long-haul COVID Plasmapheresis, Blood collection, Stool samples - Long-Haul COVID-19 | Not applicable | Withdrawn | Hôpital Européen Marseille | 2023-02-01 | 2023-08-14 | |
| Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study Plasma Exchange Procedure, Sham Plasma Exchange Procedure - Post-COVID19 Condition | Phase 2 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 50 | 2022-09-22 | 2023-06-07 |
| Plasmapheresis: a Multi-modal Approach Plasmapheresis - Plasmapheresis, Haematology | Not applicable | Completed | Université Catholique de Louvain | 70 | 2022-03-01 | 2023-04-18 |
| The Effect of Plasma Donation Frequency on Donor Health Plasmapheresis, Whole blood donation - Psychological Distress, Protein Deficiency | Not applicable | Completed | Sykehuset Innlandet HF | 120 | 2022-01-03 | 2026-01-23 |
| Mini-pool Intravenous Immunoglobulin (MP-IVIG) in Guillain-Barré Syndrome Mini-pool Intravenous Immunoglobulin (MP-IVIG), plasma exchange - Guillain-Barre Syndrome | Not applicable | Unknown | Assiut University | 50 | 2021-11-01 | 2021-01-14 |
| Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression Plasmapheresis, Plasma infusion - Mild Cognitive Impairment | Phase 1 | Completed | Mayo Clinic | 3 | 2021-09-15 | 2024-12-31 |
| Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old plasma exchange with albumin, plasma exchange without albumin - Hypercholesterolemia, Hyperbilirubinemia | Not applicable | Unknown | National Medical Research Center for Rehabilitation and Balneology | 80 | 2021-05-12 | 2021-05-21 |
Showing 20 of 64. Sign in to see all of them.
Post-Acute COVID-19 Syndrome (5) · Guillain-Barre Syndrome (3) · Amyotrophic Lateral Sclerosis (2) · Anemia, Sickle Cell (2) · COVID-19 (2) · Cardiomyopathy, Dilated (2) · Fatigue Syndrome, Chronic (2) · Glomerulosclerosis, Focal Segmental (2) · Inflammation (2) · Kidney Failure, Chronic (2) · Multiple Sclerosis (2) · Rejection, Psychology (2) · Acute Kidney Injury (1) · Anemia (1) · Carcinoma, Hepatocellular (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Assiut University (2) · Charite University, Berlin, Germany (2) · E. Steve Woodle (2) · Mayo Clinic (2) · National Taiwan University Hospital (2) · Seoul National University Hospital (2) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · University of Ulm (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Albert Christian Ludolph, Prof. (1) · Alexandria University (1) · Apheresis Research Institute (1) · Benesis Corporation (1)
United States (21) · Germany (11) · China (5) · Egypt (3) · Czechia (2) · Iran (2) · South Korea (2) · Taiwan (2) · United Kingdom (2) · Australia (1) · Belgium (1) · Canada (1) · France (1) · India (1) · Japan (1)
E. Steve Woodle, MD (2) · Johannes Dorst, Prof (2) · Akram M Fayed, MD (1) · Anil K Chandraker, MD (1) · Ann Traynor, MD (1) · Arjang Djamali, M.D. (1) · Ayman I Baess, MD (1) · Betty Diamond, MD (1) · Bevra Hahn, MD (1) · Carmen Scheibenbogen, Prof. Dr. (1) · Christopher E Simpkins, M.D. (1) · Detlef Zillikens, M. D. (1) · Ehab M El Reweny, MD (1)
PMID 16271648, PMID 21745374, PMID 22892122, PMID 23100283, PMID 26083430, PMID 26270952, PMID 29195602, PMID 31324444, PMID 31832624, PMID 36071461, PMID 36809199, PMID 37634022, PMID 37675355, PMID 38299639, PMID 38454468, PMID 38509495, PMID 38700322, PMID 39994269, PMID 40176165, PMID 42318167
1RC2HL101496 (1), U01AI063594 (1), U01AI077867 (1)