6 completed, 3 recruiting, 3 terminated, 2 not yet recruiting. 15 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 6, Recruiting 3, Terminated 3, Not yet recruiting 2, Unknown 1 |
| Phase 2 | 6 | Recruiting 2, Completed 1, Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Cancer Pain: new trials by email Literature Review of Cancer Pain trials Research Report on Cancer Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain Resiniferatoxin - Intractable Pain, Palliative Care | Phase 1 / Phase 2 | Not yet recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 30 | 2026-11-27 | 2026-10-26 |
| A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain Topical herbal plaster - Cancer Patients, Survivor Patients | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 150 | 2026-02-23 | 2026-03-04 |
| Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer Pain On the basis of conventional analgesia, patients receive treatment with Gutong Plaster. - Cancer Pains | Phase 1 / Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 198 | 2025-12-25 | 2026-06-18 |
| Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca - Chronic Insomnia, Sleep Deprivation | Phase 1 | Not yet recruiting | Nyree Penn | 100 | 2025-11-01 | 2025-05-28 |
| Phase I Study of sss40 Injection for Moderate-to-Severe Bone Metastatic Cancer Pain Injection of humanized nerve growth factor (NGF) antibody - Cancer Pain | Phase 1 / Phase 2 | Recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 132 | 2024-03-27 | 2025-06-06 |
| Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator - Nausea Post Chemotherapy, Vomiting | Phase 1 / Phase 2 | Unknown | LaSanta S A S | 334 | 2023-08-15 | 2023-02-01 |
| Study to Evaluate Safety and MTD of Epidural Resiniferatoxin Injection for Treatment of Intractable Cancer Pain Resiniferatoxin - Intractable Cancer Pain | Phase 1 | Completed | Sorrento Therapeutics, Inc. | 17 | 2017-09-01 | 2020-10-20 |
| Intranasal (NAS) Ketamine for Cancer Pain Intranasal ketamine - Cancer, Pain | Phase 1 / Phase 2 | Completed | Emory University | 10 | 2017-07-25 | 2021-09-09 |
| Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain Morphine, Oxcarbazepine - Cancer | Phase 1 | Terminated | Costantine Albany | 1 | 2014-03-06 | 2017-01-31 |
| Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain Sodium Bicarbonate - Tumor, Cancer | Phase 1 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 9 | 2013-09-01 | 2015-06-04 |
| Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer Intrathecal Resiniferatoxin - Intractable Pain, Palliative Care | Phase 1 | Completed | National Institute of Dental and Craniofacial Research (NIDCR) | 36 | 2009-08-14 | 2026-10-27 |
| Gene Transfer for Cancer Pain NP2 - Cancer Pain | Phase 1 | Completed | Diamyd Inc | 10 | 2008-02-01 | 2014-02-19 |
| Sublingual Methadone for the Management of Cancer Breakthrough Pain Methadone - Cancer, Pain | Phase 1 | Completed | AHS Cancer Control Alberta | 10 | 2003-09-01 | 2017-09-25 |
| Bioavailability and Effectiveness of Transdermally Administered Morphine morphine - Cancer, Pain | Phase 1 | Completed | Alberta Health services | 6 | 2003-07-01 | 2012-01-19 |
| Marijuana for Cancer Pain Smoked Marijuana - Neoplasms | Phase 1 / Phase 2 | Terminated | Center for Medicinal Cannabis Research | 16 | 2002-09-01 | 2013-10-10 |
Neoplasms (8) · Pain (7) · Pain, Intractable (2) · Alzheimer Disease (1) · Anxiety Disorders (1) · Breakthrough Pain (1) · Chronobiology Disorders (1) · Combat Disorders (1) · Depression (1) · Hematologic Neoplasms (1) · Idiopathic Hypersomnia (1) · Lymphoma (1) · Multiple Myeloma (1) · Neoplasm Metastasis (1)
Neurologic Manifestations (15) · Pathological Conditions, Signs and Symptoms (15) · Signs and Symptoms (15) · Pain (8) · Behavior (1) · Behavioral Symptoms (1) · Blood Protein Disorders (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Dementia (1) · Disorders of Excessive Somnolence (1) · Dyssomnias (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1)
Morphine (2) · resiniferatoxin (2) · Antibodies (1) · Dronabinol (1) · Electroencephalography (1) · Ketamine (1) · Methadone (1) · Nerve Growth Factor (1) · Oxcarbazepine (1) · Propofol (1) · Sodium Bicarbonate (1)
AHS Cancer Control Alberta (1) · Alberta Health services (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Center for Medicinal Cannabis Research (1) · Costantine Albany (1) · Diamyd Inc (1) · Emory University (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · LaSanta S A S (1) · Memorial Sloan Kettering Cancer Center (1) · National Institute of Dental and Craniofacial Research (NIDCR) (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Nyree Penn (1) · Shenyang Sunshine Pharmaceutical Co., LTD. (1) · Sorrento Therapeutics, Inc. (1)
United States (10) · China (2) · Canada (1) · Colombia (1)
John D Heiss, M.D. (2) · Neil Hagen (2) · Amit Mahipal, M.D. (1) · Costantine Albany, M.D. (1) · David J Fink, MD (1) · Donald I Abrams, M.D. (1) · Jun Mao, MD, MSCE (1) · Monica Luchi, MD (1) · Nyree Penn, MHSc., CAA, Master of Health Science (1) · Shuxia Luo (1) · Vinita Singh, MD (1)