15 completed, 4 not yet recruiting, 4 terminated, 2 recruiting. 27 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 27 | Completed 15, Not yet recruiting 4, Terminated 4, Recruiting 2, Unknown 2 |
Follow Bronchiectasis: new trials by email Literature Review of Bronchiectasis trials Research Report on Bronchiectasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn How Well People With Bronchiectasis Tolerate Continued Treatment With Verducatib After Earlier Studies (AIRTIVITY®-ON) verducatib - Bronchiectasis | Phase 3 | Not yet recruiting | Boehringer Ingelheim | 1500 | 2027-01-11 | 2026-11-12 |
| A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis CHF10196 tablets (florensocatib), Placebo - Bronchiectasis | Phase 3 | Not yet recruiting | Chiesi Farmaceutici S.p.A. | 904 | 2026-11-01 | 2026-06-24 |
| Long-Term Safety and Efficacy of Moxifloxacin in Bronchiectasis Patients Intermittent Moxifloxacin + Standard Care, Standard Care (in control arm) - Bronchiectasis, Non-Cystic Fibrosis | Phase 3 | Not yet recruiting | Assiut University | 140 | 2025-12-01 | 2025-12-10 |
| The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis BI 1291583, Placebo matching BI 1291583 - Bronchiectasis | Phase 3 | Recruiting | Boehringer Ingelheim | 1755 | 2025-06-09 | 2026-11-12 |
| ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension Clofazimine Inhalation Suspension, Placebo - MAC Lung Disease, Treatment Refractory MAC Lung Disease | Phase 3 | Terminated | Mannkind Corporation | 132 | 2024-09-11 | 2025-11-12 |
| Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention Azithromycin 40 MG/ML, Placebo - Tracheomalacia, Bronchopulmonary Dysplasia (BPD) | Phase 3 | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 150 | 2024-09-01 | 2024-05-14 |
| Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations Itraconazole 65 MG, Standard care - Bronchiectasis, Bronchiectasis Adult | Phase 3 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 80 | 2023-12-01 | 2026-10-26 |
| RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease RHB-204, Placebo - Pulmonary Mycobacterium Avium Complex Infection, Bronchiectasis | Phase 3 | Terminated | RedHill Biopharma Limited | 12 | 2020-12-01 | 2025-03-18 |
| Formoterol-beclomethasone in Patients With Bronchiectasis: a Randomized Controlled Trial Formoterol-beclomethasone, Placebo - Bronchiectasis | Phase 3 | Terminated | Erasmus Medical Center | 34 | 2019-01-29 | 2023-03-01 |
| Tobramycin in Bronchiectasis Colonized With Pseudmonas Aeruginosa Tobramycin Inhalant Product, usual care, Natural saline inhalation - Bronchiectasis Adult, Pseudomonas Infections | Phase 3 | Unknown | Guangzhou Institute of Respiratory Disease | 350 | 2018-10-26 | 2019-08-02 |
| Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR) Hypertonic saline, Carbocysteine 750 MG - Bronchiectasis | Phase 3 | Completed | Belfast Health and Social Care Trust | 288 | 2018-06-27 | 2025-05-02 |
| Effects of Traditional Chinese Medicine on Bronchiectasis Patients Bufei Huatan granule, Yifei Qinghua granule, Placebo Bufei Huatan granule - Bronchiectasis | Phase 3 | Unknown | Henan University of Traditional Chinese Medicine | 216 | 2018-03-01 | 2018-02-23 |
| Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium. CMS, Placebo - Non Cystic Fibrosis Bronchiectasis | Phase 3 | Terminated | Zambon SpA | 287 | 2018-01-29 | 2026-10-15 |
| Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis Bronchiectasis Roflumilast, Placebo - Exacerbation Copd, Bronchiectasis | Phase 3 | Completed | Prince of Songkla University | 40 | 2015-01-01 | 2019-10-10 |
| Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) Ciprofloxacin (BAYQ3939) dry powder for inhalation, Placebo - Bronchiectasis | Phase 3 | Completed | Bayer | 521 | 2014-04-30 | 2017-10-02 |
| Phase 3 Study With Ciprofloxacin Dispersion for Inhalation in Non-CF Bronchiectasis (ORBIT-3) Ciprofloxacin dispersion for inhalation, Placebo - Non Cystic Fibrosis Bronchiectasis | Phase 3 | Completed | Aradigm Corporation | 278 | 2014-03-31 | 2021-03-26 |
| Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) Ciprofloxacin DPI (BAYQ3939), Placebo - Bronchiectasis | Phase 3 | Completed | Bayer | 416 | 2013-05-02 | 2018-01-24 |
| Prevention of Bronchiectasis in Infants With Cystic Fibrosis Azithromycin, Placebo control - Cystic Fibrosis, Bronchiectasis | Phase 3 | Completed | The University of Queensland | 130 | 2012-04-01 | 2021-09-16 |
| Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis AZLI, Placebo - Bronchiectasis | Phase 3 | Completed | Gilead Sciences | 266 | 2011-04-01 | 2014-04-16 |
| Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis AZLI, Placebo - Bronchiectasis | Phase 3 | Completed | Gilead Sciences | 274 | 2011-04-01 | 2014-04-16 |
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Cough (2) · Cystic Fibrosis (2) · Lung Diseases (2) · Actinomycetales Infections (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Bronchitis, Chronic (1) · Bronchopulmonary Dysplasia (1) · Cystic Disease Of Lung (1) · Gastroesophageal Reflux (1) · Gram-Positive Bacterial Infections (1) · Idiopathic Pulmonary Fibrosis (1) · Infections (1) · Inflammation (1)
Bronchial Diseases (27) · Respiratory Tract Diseases (26) · Lung Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Diseases (3) · Infant, Newborn, Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Respiration Disorders (3) · Genetic Diseases, Inborn (2) · Infections (2) · Pancreatic Diseases (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Signs and Symptoms, Respiratory (2) · Aortic Arch Syndromes (1)
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