12 withdrawn. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Withdrawn 12 |
Follow Bipolar Disorder: new trials by email Literature Review of Bipolar Disorder trials Research Report on Bipolar Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dopamine D3 Receptor Occupancy in Bipolar Depression Cariprazine - Bipolar Depression | Phase 4 | Withdrawn | New York State Psychiatric Institute | 2026-01-06 | 2026-04-14 | |
| Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department Sublingual film containing dexmedetomidine (BXCL501) - Agitation, Schizophrenia | Phase 4 | Withdrawn | Brigham and Women's Hospital | 2023-09-01 | 2026-01-28 | |
| A PET Study With [11C]PBR-28 and an Experimental Medication, Ethyl Eicosapentaenoic Acid Ethyl Eicosapentaenoic Acid - Bipolar Disorder | Phase 4 | Withdrawn | New York State Psychiatric Institute | 2021-03-19 | 2022-10-14 | |
| Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia Suvorexant (Belsomra), Placebo - Bipolar Disorder, Insomnia | Phase 4 | Withdrawn | Massachusetts General Hospital | 2019-02-26 | 2021-02-21 | |
| A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression N-acetylcysteine, Minocycline, Placebo - Bipolar Disorder, Bipolar Depression | Phase 4 | Withdrawn | Massachusetts General Hospital | 2017-08-09 | 2026-07-24 | |
| Open-Label Study of Latuda for the Treatment of Mania in Children and Adolescents 6-17 Years Old Latuda (Lurasidone) - Mania, Bipolar I | Phase 4 | Withdrawn | Massachusetts General Hospital | 2017-01-01 | 2018-07-20 | |
| Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder Lithium - Bipolar Disorder | Phase 4 | Withdrawn | Ewha Womans University | 2015-06-01 | 2018-02-09 | |
| Lithium Versus Paroxetine in Major Depression Lithium, Paroxetine - Major Depressive Disorder | Phase 4 | Withdrawn | Nova Scotia Health Authority | 2011-09-01 | 2024-09-19 | |
| Paliperidone Palmitate Efficacy and Safety in Bipolar Disorder Complicated by Alcoholism Paliperidone Palmitate, Placebo - Bipolar Disorder | Phase 4 | Withdrawn | University of Miami | 2010-10-01 | 2014-11-21 | |
| Efficacy of Quetiapine XR Versus Divalproex on Clinical Outcome Quality of Sleep and Quality of Life in Bipolar Depression Quetiapine fumarate, Divalproex sodium - Bipolar Depression | Phase 4 | Withdrawn | Bo-Hyun Yoon | 2010-08-01 | 2012-04-27 | |
| Safety Study of Depakote Versus Lithium in African Americans With Bipolar Disorder Depakote, Lithium - Bipolar Disorder | Phase 4 | Withdrawn | Lawson, William B., M.D., PhD, DFAPA | 50 | 2006-12-01 | 2010-02-24 |
| An Evaluation of Divalproex vs. Olanzapine for Alcohol Abuse Relapse Prevention in Patients With Bipolar Disorder divalproex or olanzapine - Bipolar Disorder | Phase 4 | Withdrawn | Mayo Clinic | 2015-06-01 |
Alcoholism (1) · Depression (1) · Depressive Disorder, Major (1) · Mania (1) · Psychomotor Agitation (1) · Psychotic Disorders (1) · Schizophrenia (1) · Sleep Initiation and Maintenance Disorders (1)
Bipolar and Related Disorders (12) · Mental Disorders (12) · Mood Disorders (12) · Nervous System Diseases (3) · Behavior (2) · Behavioral Symptoms (2) · Neurobehavioral Manifestations (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Aberrant Motor Behavior in Dementia (1) · Alcohol-Related Disorders (1) · Chemically-Induced Disorders (1) · Depressive Disorder (1) · Dyskinesias (1)
Lithium (3) · Valproic Acid (3) · Acetylcysteine (1) · Docosahexaenoic Acids (1) · Lithium Carbonate (1) · Lurasidone Hydrochloride (1) · Minocycline (1) · Olanzapine (1) · Paliperidone Palmitate (1) · Paroxetine (1) · Quetiapine Fumarate (1) · cariprazine (1) · eicosapentaenoic acid ethyl ester (1) · suvorexant (1)
Massachusetts General Hospital (3) · New York State Psychiatric Institute (2) · Bo-Hyun Yoon (1) · Brigham and Women's Hospital (1) · Ewha Womans University (1) · Lawson, William B., M.D., PhD, DFAPA (1) · Mayo Clinic (1) · Nova Scotia Health Authority (1) · University of Miami (1)
United States (6) · South Korea (2) · Canada (1)
Andrew A Nierenberg, M.D. (1) · Bo-Hyun Yoon, Doctor (1) · Claire O'Donovan, MD, FRCPC (1) · Gustavo Kinrys, MD (1) · Ihsan Salloum, MD MPH (1) · Janet Wozniak, M.D. (1) · Mark A Frye, MD (1) · Martin Lan, MD (1) · William B. Lawson, MD, PhD (1)