102 completed, 24 unknown, 20 recruiting, 8 active not recruiting. 34 Phase 2, 22 Not applicable, 17 Phase 4, 16 Phase 1, 16 Phase 3.
Follow Rickets: new trials by email Literature Review of Rickets trials Research Report on Rickets
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Osteoporosis & Renal Disease: Research in Primary Health Care Services Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA) - Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder | Not yet recruiting | Universidade do Porto | 622 | 2026-10-01 | 2026-09-30 | |
| Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis intra-oral 3D optical impression - Osteogenesis Imperfecta, Rare Bone Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 240 | 2026-09-01 | 2026-06-24 |
| Treatment Patterns, Biochemical Profiles and Clinical Outcomes in Adults With X-Linked Hypophosphatemia No treatment given - X-linked Hypophosphatemia (XLH) | Withdrawn | Novo Nordisk A/S | 2026-07-07 | 2026-08-28 | ||
| Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Hypertension | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-07-01 | 2026-06-22 |
| Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane - End Stage Kidney Disease (ESKD), Hemodialysis | Not applicable | Active not recruiting | Gazi University | 30 | 2026-07-01 | 2026-09-14 |
| Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet Supplementary blood samples and urines samples - Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism | Recruiting | Hospices Civils de Lyon | 20 | 2026-04-29 | 2026-05-22 | |
| The CPH-MBD Cohort Chronic Kidney Disease Mineral and Bone Disorder, Chronic Kidney Disease (CKD) | Recruiting | Herlev Hospital | 1000 | 2026-01-07 | 2026-09-16 | |
| The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations CKD, Renal Insufficiency Chronic | Recruiting | University of Copenhagen | 50 | 2025-12-15 | 2025-12-31 | |
| The Effect of REgulation of PArathyroId hoRmone in Patients With Chronic Kidney Disease to Investigate the Change in Bone Mineral Density Treat to target - Chronic Kidney Disease Mineral and Bone Disorder | Not applicable | Recruiting | Herlev Hospital | 70 | 2025-11-20 | 2026-01-06 |
| Effective Dosing of Burosumab in XLH X-linked Hypophosphatemia (XLH) | Recruiting | University of Nottingham | 120 | 2025-11-03 | 2026-05-11 | |
| Activated Charcoal Use in Chronic Kidney Disease Patients Activated Charcoal, Phosphate Binders - End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis | Phase 2 | Recruiting | Mansoura University | 40 | 2025-08-01 | 2025-08-08 |
| Phosphorus-31 Spectroscopy in Phosphate Diabetes intra-muscular ATP values in phosphate diabetes, intra-muscular phosphate values in phosphate diabetes - Phosphate Diabetes, X-linked Hypophosphatemia | Not applicable | Recruiting | Hospices Civils de Lyon | 65 | 2025-05-16 | 2026-07-23 |
| Phosphate Assessment in Chronic Kidney Disease Patients Study Dietary Phosphorus Intake - Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 60 | 2025-05-09 | 2026-01-28 |
| Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients Hemodyalysis, Kidney Tansplant | Recruiting | Grigore T. Popa University of Medicine and Pharmacy | 180 | 2025-03-19 | 2025-08-26 | |
| Effects of Aerobic Versus Resistance Training on Bone Metabolism in Stage 3-4 Chronic Kidney Disease Resistance Exercise, Aerobic Training - Osteopenia, Bone Metabolism Disorders | Not applicable | Completed | Sinai University | 60 | 2025-01-01 | 2025-08-21 |
| A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia KK8123 - X-linked Hypophosphatemia | Phase 1 / Phase 2 | Recruiting | Kyowa Kirin Co., Ltd. | 39 | 2024-10-09 | 2026-09-21 |
| Effect of Burosumab on the Inflammatory Profile of Patients With X-linked Hypophosphatemic Rickets FLAM-XLH Expression of inflammatory markers (Il6, Il8, Il1β, CXCL1, CCL2, CXCR3, Il1R, Il6R) - X-Linked Hypophosphatemic Rickets | Unknown | Hospices Civils de Lyon | 20 | 2024-04-01 | 2024-03-06 | |
| Ultrasound Imaging and Quantitative Vibro-Acoustic Assessment of Rickets Under the Age of Ten Ultrasound with quantitative vibro-acoustic assessment - Rickets | Withdrawn | Mayo Clinic | 2024-03-13 | 2024-12-16 | ||
| DePTH: De-emphasize PTH Oral calcitriol with cinacalcet rescue, IV activated vitamin D - Kidney Failure, Chronic, Chronic Kidney Disease-Mineral and Bone Disorder | Phase 2 | Active not recruiting | University of Washington | 90 | 2024-03-11 | 2025-06-02 |
| Post Marketing Surveillance Study to Observe Safety and Effectiveness of CRYSVITA® in S. Korean Patients FGF23-related hypophosphataemic rickets and osteomalacia - FGF23-related Hypophosphataemic Rickets and Osteomalacia | Recruiting | Kyowa Kirin Korea Co., Ltd. | 100 | 2023-08-11 | 2025-08-29 |
Showing 20 of 172. Sign in to see all of them.
Chronic Kidney Disease-Mineral and Bone Disorder (73) · Familial Hypophosphatemic Rickets (49) · Osteomalacia (34) · Renal Insufficiency, Chronic (28) · Bone Diseases (23) · Hyperparathyroidism, Secondary (16) · Hypophosphatasia (14) · Hypophosphatemia (13) · Kidney Failure, Chronic (13) · Vitamin D Deficiency (13) · Osteoporosis (11) · Rickets, Hypophosphatemic (9) · Bone Diseases, Metabolic (7) · Hyperphosphatemia (7)
Avitaminosis (172) · Calcium Metabolism Disorders (172) · Deficiency Diseases (172) · Nutrition Disorders (172) · Nutritional and Metabolic Diseases (172) · Metabolic Diseases (171) · Musculoskeletal Diseases (171) · Malnutrition (170) · Bone Diseases, Metabolic (165) · Vitamin D Deficiency (159) · Bone Diseases (149) · Female Urogenital Diseases and Pregnancy Complications (125) · Female Urogenital Diseases (124) · Male Urogenital Diseases (124)
burosumab (22) · asfotase alfa (10) · Calcitriol (8) · Cholecalciferol (8) · Blood Specimen Collection (4) · Cinacalcet (4) · Ergocalciferols (4) · Vitamin D (4) · Calcium (3) · Calcium Carbonate (3) · Denosumab (3) · Phosphates (3) · Sevelamer (3) · etelcalcetide hydrochloride (3) · 1 alpha-hydroxyergocalciferol (2)
Alexion Pharmaceuticals, Inc. (13) · Kyowa Kirin Co., Ltd. (11) · Kyowa Kirin, Inc. (6) · Hospices Civils de Lyon (5) · Kyowa Kirin Pharmaceutical Development Ltd (5) · Mayo Clinic (5) · Yale University (5) · National Institute of Dental and Craniofacial Research (NIDCR) (4) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (4) · Assistance Publique - Hôpitaux de Paris (3) · Herlev Hospital (3) · University of Aarhus (3) · University of Sao Paulo General Hospital (3) · Bicetre Hospital (2) · Children's Mercy Hospital Kansas City (2)
United States (62) · France (21) · United Kingdom (18) · Canada (17) · China (14) · Denmark (13) · Germany (12) · Japan (12) · Italy (7) · Spain (7) · Turkey (Türkiye) (7) · Netherlands (6) · South Korea (6) · Australia (5) · Austria (5)
Amy Zhang, PhD (2) · Ditte Hansen, MD, PhD (2) · Ditte Hansen, Medical doctor, professor (2) · Jing Chen, MD (2) · Tadao Akizawa, MD, PhD (2) · Thomas D Thacher, MD (2) · Thomas Nickolas, MD, MS (2) · Yongjun Wang, Doctor (2) · Aihua Zhang (1) · Aili Jiang (1) · Alison M Boyce, M.D. (1) · Anat Tsur, MD (1)
PMID 39151033, PMID 26529632, PMID 40576086, PMID 32417537, PMID 32721016, PMID 32762706, PMID 40962182, PMID 25919461, PMID 27699270, PMID 33305842, PMID 36854566, PMID 15930998, PMID 18385391, PMID 18397701, PMID 19244376, PMID 19480654, PMID 19776051, PMID 19778452, PMID 20056760, PMID 20724326, PMID 21426510, PMID 22397652, PMID 22994525, PMID 23256143, PMID 24120120, PMID 24290111, PMID 24569459, PMID 24748637, PMID 25029424, PMID 25112372, PMID 25874620, PMID 26073451, PMID 26546060, PMID 26675779, PMID 27647184, PMID 27768855, PMID 28822957, PMID 29486367, PMID 29791829, PMID 29947083, PMID 30558909, PMID 30638856, PMID 30811537, PMID 30969260, PMID 31104833, PMID 31165191, PMID 31315600, PMID 31652009, PMID 31774125, PMID 32601114
1RC1HD063562 (1), 1UL1TR001863-01 (1), 2014 (1), 2018 (1), K23DK136930 (1), P50AR054086 (1), R01DK080770 (1), R01DK110871 (1), R01DK134101 (1), R21AR061818 (1), R21AR075370 (1), R21DK074105 (1)