80 completed, 12 unknown, 6 terminated, 5 withdrawn. 109 Phase 3, 28 Phase 2.
Follow Avitaminosis: new trials by email Literature Review of Avitaminosis trials Research Report on Avitaminosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support Choline Chloride for Injection, Placebo - Choline Deficiency, Liver Injury | Phase 2 / Phase 3 | Recruiting | Protara Therapeutics | 129 | 2025-12-10 | 2026-08-24 |
| OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity 0.75% Phentolamine Ophthalmic Solution, Placebo - Vision Loss Night, Vision Disorders | Phase 3 | Recruiting | Opus Genetics, Inc | 580 | 2025-09-02 | 2026-10-14 |
| Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances phentolamine ophthalmic solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist, Placebo - Mesopic Vision, Night Vision Loss | Phase 3 | Completed | Opus Genetics, Inc | 200 | 2024-04-01 | 2026-10-26 |
| Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os - Obesity, Childhood | Phase 3 | Recruiting | Hospices Civils de Lyon | 68 | 2023-12-04 | 2025-06-13 |
| Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism CTAP101, Placebo - Chronic Kidney Disease stage3, Chronic Kidney Disease stage4 | Phase 3 | Terminated | OPKO Health, Inc. | 2 | 2023-01-31 | 2025-07-25 |
| Vitamin D, Oxidative Stress and Inflammation in Hemodialysis Cholecalciferol - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Ain Shams University | 25 | 2022-05-15 | 2023-02-06 |
| Cholecalciferol Supplementation in Hemodialysis Patients Cholecalciferol - Anemia, Hemodialysis Complication | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2022-05-15 | 2023-06-28 |
| Effectiveness of Vitamin C Supplementation in Treatment of Rickets Vit C - Nutritional Rickets, Bone Turnover Rate Disorder | Phase 2 / Phase 3 | Completed | Cairo University | 88 | 2022-03-01 | 2023-03-08 |
| Early Infant Micronutrition and Development Cyanocobalamin - Vitamin B 12 Deficiency | Phase 2 / Phase 3 | Recruiting | Sykehuset Innlandet HF | 600 | 2021-12-08 | 2023-04-18 |
| Impact of Vitamin D3 Supplementation in Non-Sjogren Dry Eye Patients With Low Serum Vitamin D Level Vitamin D, Artificial tear - Dry Eye Syndromes, Hypovitaminosis D | Phase 3 | Completed | University of Faisalabad | 108 | 2021-11-01 | 2022-06-21 |
| Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT adhesive system, fluoride varnish, flowable composite - X-linked Hypophosphatemia (XLH) | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 60 | 2021-06-01 | 2021-05-05 |
| Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury Cholecalciferol (Vitamin D3), Placebo - Spinal Cord Injuries, Vitamin D Deficiency | Phase 3 | Completed | Swiss Paraplegic Research, Nottwil | 50 | 2021-05-19 | 2024-03-08 |
| The Effect of Vitamin D3 Therapy on Vitamin D Status in Pregnant Women With Vitamin D Deficient and Insufficient Cholecalciferol - Vitamin D Deficiency | Phase 2 / Phase 3 | Unknown | Universitas Indonesia | 52 | 2021-04-01 | 2023-09-26 |
| Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa). Teriparatide - Secondary Hyperparathyroidism, Chronic Kidney Disease-Mineral and Bone Disorder | Phase 3 | Completed | Saint Petersburg State University, Russia | 20 | 2021-03-01 | 2022-11-10 |
| Anti-FGF23 (Burosumab) in Adult Patients With XLH Burosumab - X-linked Hypophosphatemia | Phase 3 | Completed | Wuerzburg University Hospital | 36 | 2021-01-07 | 2023-05-03 |
| Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency Calcifediol 75mcg, Calcifediol 100mcg, Calcifediol 125mcg - Vitamin D Deficiency, Vitamin D Insufficiency | Phase 2 / Phase 3 | Completed | Faes Farma, S.A. | 674 | 2020-12-23 | 2023-09-15 |
| Vitamin D 24'000 IU for Oral Intermittent Supplementation Vitamin D3, Vitamin D oily capsules - Vitamin D Deficiency | Phase 3 | Completed | University Hospital, Basel, Switzerland | 58 | 2019-09-30 | 2020-06-04 |
| Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs Thiamine Mononitrate - Heart Diseases | Phase 3 | Unknown | Mahidol University | 60 | 2019-07-01 | 2019-06-20 |
| Rapid Normalization of Vitamin D Deficiency in PICU Cholecalciferol, Placebo - Vitamin D Deficiency | Phase 3 | Completed | Children's Hospital of Eastern Ontario | 424 | 2019-06-17 | 2025-02-12 |
| Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH Burosumab - X-linked Hypophosphatemia | Phase 3 | Completed | Kyowa Kirin Pharmaceutical Development Ltd | 35 | 2019-03-07 | 2022-05-20 |
Showing 20 of 109. Sign in to see all of them.
Vitamin D Deficiency (73) · Vitamin A Deficiency (10) · Familial Hypophosphatemic Rickets (8) · Critical Illness (7) · Hyperparathyroidism, Secondary (6) · Renal Insufficiency, Chronic (6) · Kidney Diseases (5) · Osteoporosis (5) · Rickets (5) · Hyperhomocysteinemia (4) · Hyperparathyroidism (4) · Renal Insufficiency (4) · Anemia (3) · Breast Feeding (3)
Deficiency Diseases (109) · Nutrition Disorders (109) · Nutritional and Metabolic Diseases (109) · Malnutrition (108) · Metabolic Diseases (32) · Pathological Conditions, Signs and Symptoms (32) · Pathologic Processes (25) · Urogenital Diseases (24) · Female Urogenital Diseases and Pregnancy Complications (23) · Musculoskeletal Diseases (23) · Female Urogenital Diseases (21) · Bone Diseases (20) · Bone Diseases, Metabolic (20) · Calcium Metabolism Disorders (20)
Cholecalciferol (47) · Vitamin D (14) · burosumab (7) · Calcifediol (6) · Vitamin A (4) · Calcium Carbonate (3) · Ergocalciferols (3) · Sugars (3) · Vitamin B 12 (3) · paricalcitol (3) · Alendronate (2) · Calcitriol (2) · Duration of Therapy (2) · 1 alpha-hydroxyergocalciferol (1) · 25-hydroxyvitamin D (1)
Johns Hopkins Bloomberg School of Public Health (4) · Medical University of Graz (4) · Ain Shams University (3) · Kyowa Kirin, Inc. (3) · Massachusetts General Hospital (3) · Medical University of South Carolina (3) · University of Tromso (3) · American University of Beirut Medical Center (2) · Centre For International Health (2) · London School of Hygiene and Tropical Medicine (2) · Mahidol University (2) · OPKO Health, Inc. (2) · OPKO IP Holdings II, Inc. (2) · Opus Genetics, Inc (2) · Semmelweis University (2)
United States (38) · France (9) · Austria (6) · Canada (6) · Japan (6) · United Kingdom (6) · Italy (5) · China (4) · Egypt (4) · Germany (4) · Norway (4) · Saudi Arabia (4) · Bangladesh (3) · Denmark (3) · South Korea (3)
Joel Melnick, MD (3) · Alfred Sommer, M.D. (2) · Amanda C Palmer, PhD (2) · Tor A Strand, MD/PhD (2) · Abdul Hakim Nattouf, MD, PhD (1) · Adekunle Dawodu, MBBS (1) · Akhtar Ashfaq, MD (1) · Alain B Labrique, MSc (1) · Alain B. Labrique, MSc (1) · Alain Labrique, PhD (1) · Albina Nowak, MD (1) · Andrea Kelly, MD (1) · Anke Scheel-Sailer, Dr. med. (1)
PMID 33305842, PMID 39151033, PMID 28490513, PMID 36854566, PMID 39077939, PMID 16973975, PMID 18625626, PMID 18689371, PMID 18697901, PMID 19386744, PMID 19480654, PMID 19776145, PMID 19829124, PMID 20141576, PMID 20237066, PMID 20435345, PMID 20719580, PMID 20941903, PMID 20977661, PMID 21197089, PMID 21510905, PMID 21586714, PMID 21628633, PMID 21706518, PMID 21791335, PMID 21832026, PMID 21857221, PMID 22071710, PMID 22077475, PMID 22218721, PMID 22412025, PMID 22467697, PMID 22494826, PMID 22784845, PMID 22790678, PMID 22955514, PMID 23151532, PMID 23256143, PMID 23559082, PMID 23719555, PMID 24289974, PMID 24290111, PMID 24455219, PMID 25029424, PMID 25268295, PMID 25527663, PMID 25646326, PMID 25679979, PMID 25872802, PMID 26201817
2014 (1), 2018 (1), 2019 (1), K23DK087859 (1), P50AR054086 (1), R01AG019147 (1), R01DK084986 (1), R01HD043921 (1), R01HD047511 (1), R01HL069272 (1), U01HL123009 (1)