905 completed. 905 Phase 2, 114 Phase 1, 77 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 905 | Completed 905 |
| Phase 1 | 114 | Completed 114 |
| Phase 3 | 77 | Completed 77 |
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Umbilical Cord Mesenchymal Stromal Cell Secretome for Moderate Rheumatoid Arthritis Umbilical Cord-Derived Mesenchymal Stromal Cell (UC-MSC) Secretome, Placebo (Normal Saline) - Rheumatoid Arthritis | Phase 2 | Completed | Universitas Sriwijaya | 40 | 2026-02-04 | 2026-09-16 |
| Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare ABP-745 Dose A, ABP-745 Dose B, Colchicine - Acute Gouty Arthritis, Gout Flare | Phase 2 | Completed | Atom Therapeutics Co., Ltd | 479 | 2025-08-26 | 2026-10-28 |
| A Phase 1/2a Study to Evaluate Single Intraarticular Injections of 3 Dose Levels of SYN321 and Placebo in Patients With Symptomatic Knee Osteoarthritis SYN321, Placebo - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Synartro AB | 35 | 2025-08-19 | 2026-03-06 |
| A Study With CIT-013 in RA Patients CIT-013 low dose, CIT-013 high dose, Placebo - Rheumatoid Arthritis | Phase 2 | Completed | Citryll BV | 96 | 2025-07-29 | 2026-10-19 |
| Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis L-carnitine, Placebo - Knee Osteoarthritis | Phase 2 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 66 | 2025-06-28 | 2026-02-06 |
| A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis 4P004, Placebo (NaCl 0.9%) - Knee Osteoarthritis, Synovitis of Knee | Phase 2 | Completed | 4Moving Biotech | 130 | 2025-06-17 | 2026-10-23 |
| EF-M2 (Immutalon) Multiple Ascending Dose Study in Moderate-to-Severe Rheumatoid Arthritis EF-M2 - Rheumatoid Arthritis | Phase 1 / Phase 2 | Completed | S.LAB (SOLOWAYS) | 48 | 2025-06-03 | 2026-01-16 |
| Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients Febuxostat Tablets, Metformin - Gout | Phase 2 | Completed | Mostafa Bahaa | 60 | 2025-05-30 | 2026-09-17 |
| A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee Cryopreserved Devitalized Adipose Tissue Allograft, Normal Saline (Placebo) - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Britecyte | 46 | 2025-05-05 | 2026-09-08 |
| Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981 CKD-981(1), CKD-981(2), Sham device - Knee Osteoarthritis | Phase 2 | Completed | Chong Kun Dang Pharmaceutical | 100 | 2025-04-28 | 2026-04-13 |
| A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance Along With Pharmaceutical and Non-pharmaceutical Therapy in the Early Rheumatoid Arthritis Clinical Pharmacist Led Intervention, DMARD Therapy - Early Rheumatoid Arthritis | Phase 2 / Phase 3 | Completed | Deraya University | 70 | 2025-04-10 | 2026-07-24 |
| Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty Morphine, Vancomycin - Primary Total Knee Arthroplasty, Intraosseous Morphine Injection | Phase 2 | Completed | Carilion Clinic | 100 | 2024-12-01 | 2025-09-10 |
| Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, 2.5% Diclofenac Patches - Osteo Arthritis Knee, Arthritis | Phase 2 | Completed | ZetrOZ, Inc. | 307 | 2024-10-01 | 2026-06-30 |
| Proximod, a Selective Sphingosine-1-phosphate Receptor 1 Modulator in Patients With Moderate-to-severe Active Rheumatoid Arthritis: a Double-blind, Randomised, Placebo-controlled, Phase 2 Trial. proximod 5mg daily, proximod 10mg daily - Rheumatoid Arthritis | Phase 2 | Completed | Peking University People's Hospital | 179 | 2024-09-02 | 2026-01-13 |
| Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients With Rheumatoid Arthritis FBL-MTX - Rheumatoid Arthritis | Phase 2 | Completed | SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd | 40 | 2024-07-24 | 2026-09-25 |
| A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects Febuxostat, IBI128 - Gout, Hyperuricemia | Phase 2 | Completed | Innovent Biologics (Suzhou) Co. Ltd. | 84 | 2024-07-10 | 2025-03-27 |
| Effectiveness of Platelet-rich Plasma Treatment of Knee Osteoarthritis Platelet-Rich Plasma - Knee Osteoarthritis | Phase 2 | Completed | Universidad Nacional de Entre Rios | 111 | 2024-05-01 | 2026-09-15 |
| Umbilical Cord Mesenchymal Stem Cell Secretome in Patients With Sjogren's Syndrome Umbilical cord mesenchymal stem cell-derived secretome, Placebo (0.9% sodium chloride) - Sjogren's Syndrome | Phase 1 / Phase 2 | Completed | Universitas Sebelas Maret Hospital | 29 | 2024-05-01 | 2026-11-02 |
| A Clinical Study of JS005 in Patients With Ankylosing Spondylitis Recombinant humanized IL-17A Monoclonal Antibody（JS005）, Placebo（JS005） - Ankylosing Spondylitis | Phase 2 | Completed | Shanghai Junshi Bioscience Co., Ltd. | 265 | 2024-01-13 | 2026-07-20 |
| Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis Autologous Alpha-2 Macroglobulin Rich Plasma (A2MRP) - Osteoarthritis, OA | Phase 1 / Phase 2 | Completed | Mayo Clinic | 20 | 2024-01-09 | 2026-02-12 |
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Arthritis, Rheumatoid (374) · Osteoarthritis (218) · Osteoarthritis, Knee (207) · Gout (55) · Pain (49) · Sjogren's Syndrome (38) · Arthritis, Psoriatic (33) · Spondylitis, Ankylosing (30) · Hyperuricemia (27) · Joint Diseases (25) · Inflammation (18) · Arthritis, Juvenile (16) · Autoimmune Diseases (16) · Musculoskeletal Diseases (14)
Musculoskeletal Diseases (891) · Joint Diseases (880) · Rheumatic Diseases (816) · Skin and Connective Tissue Diseases (475) · Connective Tissue Diseases (436) · Immune System Diseases (432) · Autoimmune Diseases (417) · Pathological Conditions, Signs and Symptoms (140) · Osteoarthritis (130) · Signs and Symptoms (75) · Pathologic Processes (72) · Metabolic Diseases (70) · Nutritional and Metabolic Diseases (70) · Bone Diseases (68)
Methotrexate (49) · Adalimumab (21) · Febuxostat (16) · Rituximab (16) · Hyaluronic Acid (15) · Saline Solution (15) · tofacitinib (15) · Sodium Chloride (14) · Allopurinol (13) · Colchicine (13) · Naproxen (13) · Folic Acid (12) · canakinumab (12) · GLPG0634 (10) · Etanercept (9)
Pfizer (33) · Novartis Pharmaceuticals (24) · Amgen (19) · GlaxoSmithKline (18) · AbbVie (15) · Eli Lilly and Company (15) · Bristol-Myers Squibb (12) · Lakefront Biotherapeutics NV (11) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (11) · Pacira Pharmaceuticals, Inc (10) · Janssen Research & Development, LLC (9) · Takeda (9) · AstraZeneca (8) · Novartis (8) · Sanofi (8)
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