19 completed. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 19 |
Follow Appendicitis: new trials by email Literature Review of Appendicitis trials Research Report on Appendicitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lidocaine VS Hemodynamic, Metabolic and Hormonal Response Intravenous lidocaine, Normal saline infusion - Hemodynamic Response, Acute Appendicitis | Phase 4 | Completed | Medical University of Warsaw | 132 | 2022-03-12 | 2023-10-31 |
| Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy Antibiotics, cefuroxime and metronidazole, No antibiotics, urgent schedule - Appendicitis | Phase 4 | Completed | Helsinki University Central Hospital | 1800 | 2020-05-18 | 2023-07-11 |
| Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy Lidocaine - Acute Appendicitis, Postoperative Pain | Phase 4 | Completed | Medical University of Warsaw | 74 | 2019-03-22 | 2020-05-19 |
| COMPARISON OF TRANSVERSUS ABDOMINIS PLANE BLOCK, LOCAL ANESTHETIC INJECTION TO THE PORT SITES AND INTRAPERITONEAL LOCAL ANESTHESIA APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN PATIENTS WITH LAPAROSCOPIC APPENDECTOMY Bupivacaine - Postoperative Pain | Phase 4 | Completed | Fatih Sultan Mehmet Training and Research Hospital | 3 | 2018-11-01 | 2021-03-23 |
| Acute Appendicitis: Active Observation With and Without Antibiotics Antibiotic treatment (Piperacillin/Tazobactam, 4 gram x 3), followed by 8-10 days of out-hospital oral antibiotic treatment (Ciprofloxacin 500 mgx2,Flagyl 400 mgx3)., Active observation - Appendicitis | Phase 4 | Completed | Göteborg University | 126 | 2018-05-15 | 2022-08-16 |
| Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult Bupivacaine - Appendicitis Acute | Phase 4 | Completed | National Taiwan University Hospital | 47 | 2018-04-23 | 2020-04-27 |
| Optimal Care of Complicated Appendicitis Early Appendectomy, Interval Appendectomy, Antibiotics - Appendicitis, Perforated Appendicitis | Phase 4 | Completed | University of Michigan | 40 | 2017-06-29 | 2023-11-28 |
| Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis Piperacillin, Tazobactam Drug Combination - Perforated Appendicitis, Postoperative Infection | Phase 4 | Completed | Phoenix Children's Hospital | 162 | 2017-05-22 | 2024-01-12 |
| Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children Piperacillin/Tazobactam, Surgical Treatment - Appendicitis | Phase 4 | Completed | NYU Langone Health | 39 | 2016-12-01 | 2022-01-21 |
| Appendicectomy Skin Closure Technique: Changing Paradigms (ASC) Continuous intradermic stitch, Separated stitches - Appendicitis | Phase 4 | Completed | María Valeria Jiménez Baez | 200 | 2015-04-01 | 2016-05-27 |
| Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children Ropivacaine - Pain, Postoperative, Appendicitis | Phase 4 | Completed | Hospital Infantil Albert Sabin | 40 | 2015-01-01 | 2016-12-30 |
| A Comparison of UGBRS Block and Local Infiltration UGBRSB, Local Infiltration - Appendicitis | Phase 4 | Completed | Baylor College of Medicine | 50 | 2011-04-01 | 2015-07-21 |
| Non Operative Treatment for Acute Appendicitis Amoxicillin and Clavulanic Acid - Lower Abdominal Pain, Right Iliac Fossa Pain | Phase 4 | Completed | Maggiore Bellaria Hospital, Bologna | 160 | 2010-01-01 | 2011-07-27 |
| Wound Healing After Emergency Appendicectomy appendicectomy - Appendicitis | Phase 4 | Completed | Tampere University Hospital | 200 | 2009-07-01 | 2010-06-11 |
| Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General Surgeon Morphine - Appendicitis | Phase 4 | Completed | Seoul National University Hospital | 234 | 2008-10-01 | 2011-07-26 |
| Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) tigecycline, ceftriaxone plus metronidazole - Appendicitis, Cholecystitis | Phase 4 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 473 | 2005-10-01 | 2013-02-25 |
| Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection tigecycline, ceftriaxone sodium + metronidazole - Appendicitis, Cholecystitis | Phase 4 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 467 | 2005-09-01 | 2013-02-25 |
| Morphine Analgesia in Patients With Acute Appendicitis Morphine - Appendicitis | Phase 4 | Completed | Tehran University of Medical Sciences | 71 | 2004-01-01 | 2007-05-22 |
| Laparoscopic Versus Open Appendectomy Open appendectomy, Laparoscopic appendectomy - Acute Appendicitis | Phase 4 | Completed | University of Catania | 593 | 2004-01-01 | 2016-08-16 |
Pain, Postoperative (3) · Cholecystitis (2) · Diverticulitis (2) · Peritonitis (2) · Abdominal Abscess (1) · Abscess (1) · Agnosia (1) · Cross Infection (1) · Disease (1) · Intraabdominal Infections (1) · Pain (1) · Pneumoperitoneum (1) · Postoperative Nausea and Vomiting (1) · Recurrence (1)
Cecal Diseases (19) · Digestive System Diseases (19) · Gastroenteritis (19) · Gastrointestinal Diseases (19) · Infections (19) · Intestinal Diseases (19) · Intraabdominal Infections (18) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (7) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Pain (3) · Peritoneal Diseases (3) · Postoperative Complications (3) · Biliary Tract Diseases (2)
Metronidazole (5) · Piperacillin, Tazobactam Drug Combination (4) · Appendectomy (3) · Anti-Bacterial Agents (2) · Bupivacaine (2) · Ceftriaxone (2) · Ciprofloxacin (2) · Morphine (2) · Piperacillin (2) · Tazobactam (2) · Tigecycline (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Anesthesia, Local (1) · Cefuroxime (1) · Lidocaine (1)
Medical University of Warsaw (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · Baylor College of Medicine (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · Göteborg University (1) · Helsinki University Central Hospital (1) · Hospital Infantil Albert Sabin (1) · Maggiore Bellaria Hospital, Bologna (1) · María Valeria Jiménez Baez (1) · NYU Langone Health (1) · National Taiwan University Hospital (1) · Phoenix Children's Hospital (1) · Seoul National University Hospital (1) · Tampere University Hospital (1) · Tehran University of Medical Sciences (1)
United States (5) · Finland (3) · Brazil (2) · Italy (2) · Poland (2) · Taiwan (2) · Turkey (Türkiye) (2) · Argentina (1) · Australia (1) · Canada (1) · Chile (1) · China (1) · Denmark (1) · France (1) · Germany (1)
Andrea Biscardi, MD (1) · Asieh Golozar, MD (1) · Chih-Yang Hsiao, M.D. (1) · Eleonora Giorgini, MD (1) · Franco Baldoni, MD (1) · Gianluca Senatore, MD (1) · Gregorio Tugnoli, MD (1) · Jason Fisher, MD (1) · Justin Lee, MD (1) · Kent Lundholm, Professor (1) · Maria Valeria Jimenez Baez, PhD (1) · Nicola Antonacci, MD (1) · Nicola Clemente, MD (1)
PMID 18723709, PMID 20670293, PMID 22021722, PMID 22439781, PMID 24646528, PMID 27283187, PMID 27582784, PMID 33397287, PMID 34580704, PMID 35982198, PMID 37717589, PMID 39794723, PMID 41226876
2019 (1)