16 completed, 8 recruiting, 7 not yet recruiting, 7 unknown. 14 Phase 4, 10 Not applicable, 6 Phase 3, 1 Phase 2.
Follow Antibiotic Prophylaxis: new trials by email Literature Review of Antibiotic Prophylaxis trials Research Report on Antibiotic Prophylaxis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antibiotics for Kidney Transplant Recipients Trimethoprim-Sulfamethoxazole (TMP-SMX), Usual Care - Kidney Transplant, Urinary Tract Infection(UTI) | Phase 4 | Not yet recruiting | University of California, San Francisco | 50 | 2028-10-01 | 2026-09-11 |
| Prediction and Prevention of Bloodstream Infections After Kidney Transplantation Pivmecillinam, Placebo - Kidney Transplant Infection, Bloodstream Infection | Phase 3 | Not yet recruiting | Susanne Dam Nielsen, MD, DMSc | 180 | 2027-01-01 | 2026-10-16 |
| Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic Diseases Amoxicillin, Placebo - Autoimmune Rheumatic Diseases, Tooth Extraction | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 352 | 2026-10-07 | 2026-10-15 |
| Perioperative Pharmacokinetic/Pharmacodynamic Target Attainment of Piperacillin During Major Hepatic and Pancreatic Surgery Antibiotic Prophylaxis, Pancreatic Surgey | Recruiting | Central Hospital, Nancy, France | 60 | 2026-09-25 | 2026-10-02 | |
| Immunoglobulin Replacement Therapy (IgRT) Versus Antibiotic Prophylaxis (PA) in Patients Treated by CD19-targeted Chimeric Antigen Receptor (CAR)T Cells for a B Cell Acute Lymphoblastic Leukemia or a B Cell Lymphoma Immunoglobulin, antibiotic prophylaxis - Chimeric Antigen Receptor T-cell Therapy, B Cell Acute Lymphoblastic Leukemia (B-ALL) | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 228 | 2026-09-01 | 2026-08-10 |
| Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve Implantation Cefazolin antibiotic prophylaxis - Hydrocephaly, CSF Shunts | Not applicable | Recruiting | University Hospital, Strasbourg, France | 15 | 2026-02-01 | 2026-08-20 |
| Antibiotic Prophylaxis Versus Placebo in Alveolar Bone Grafting: A Randomized Controlled Trial Amoxicillin 500 mg (prophylactic regimen), Placebo Capsule (matched dosing schedule) - Alveolar Ridge Augmentation, Bone Grafting | Not applicable | Not yet recruiting | Agnaldo Rocha de Souza Junior | 150 | 2026-02-01 | 2025-12-29 |
| Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery antibiotic prophylaxis - BPH With Urinary Obstruction, Antibiotic Prophylaxis | Phase 3 | Not yet recruiting | Ohio State University | 250 | 2026-01-01 | 2025-10-06 |
| Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study Premature Rupture of Membranes, Enterobacteriaceae | Not yet recruiting | Centre Hospitalier de Saint-Denis | 250 | 2025-10-01 | 2025-10-01 | |
| Azithromycin and Ampicillin for Late PPROM Intravenous Ampicillin followed by Oral Amoxicillin, Ampicillin/Amoxicillin plus single-dose PO Azithromycin - Pregnancy Complications, Infectious, Premature Birth | Phase 4 | Recruiting | Sheba Medical Center | 311 | 2025-09-10 | 2025-12-18 |
| Infection-related Revision Rates After Single-dose Versus Multiple-dose Antibiotic Prophylaxis in Primary Hip and Knee Arthroplasty: a Comparative Implementation Study. Total Hip Arthroplasty (THA), Antibiotic Prophylaxis | Enrolling by invitation | JointResearch | 70000 | 2025-06-01 | 2025-07-08 | |
| STI Prophylaxis and Emergence of Antimicrobial Resistance Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis | Recruiting | University College, London | 108 | 2025-02-10 | 2025-03-27 | |
| Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO) - Dysbiosis, Gut -microbiota | Phase 4 | Not yet recruiting | Acibadem Maslak Hospital | 60 | 2025-02-01 | 2025-01-24 |
| Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis Pivmecillinam, Amoxicillin clavulanic acid, Amoxicillin - Cystectomy, Bladder Cancer Requiring Cystectomy | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 248 | 2025-01-07 | 2025-01-09 |
| Linezolid or Vancomycin Surgical Site Infection Prophylaxis Vancomycin Injection, Linezolid Injection - Antibiotic Prophylaxis, General Surgery | Phase 4 | Recruiting | Assistance Publique Hopitaux De Marseille | 1160 | 2024-11-12 | 2026-02-05 |
| The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients Cefazolin 1000 MG - Antibiotic Prophylaxis, Wound Infection | Phase 3 | Unknown | University of Aleppo | 200 | 2024-08-01 | 2024-08-28 |
| Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation Ampicillin sulbactam 3 days, Placebo 3 days - Heart Block, CIED Related Infection | Phase 4 | Completed | Universitas Diponegoro | 60 | 2024-04-01 | 2025-02-27 |
| Antibiotic Prophylaxis in Lung-Transplant Recipients Lung-transplant Recipients, Antibiotic Prophylaxis | Completed | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 90 | 2024-01-12 | 2025-01-10 | |
| Prenatal Antibiotics and Breast Milk / Neonatal IgA Antibiotics - Prenatal Exposure Delayed Effects, Antibiotic Prophylaxis | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 82 | 2023-10-08 | 2024-06-26 | |
| Evaluation of the Effect of Antibiotic Prophylaxis (2g Amoxicillin One Hour Before Surgery) on an Inflammatory Factor (PGE2) in Salivary Samples After Third Molars Surgery Amoxicillin, Placebo - Healthy, Third Molar Extraction Surgery | Phase 4 | Completed | Universidad Católica San Antonio de Murcia | 18 | 2023-10-05 | 2024-09-26 |
Showing 20 of 45. Sign in to see all of them.
Surgical Wound Infection (6) · Urinary Tract Infections (4) · Bacterial Infections (2) · Dysbiosis (2) · Infections (2) · Wound Infection (2) · Acute Kidney Injury (1) · Bacteriuria (1) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Fetal Membranes, Premature Rupture (1) · Heart Block (1) · Hernia, Inguinal (1) · Homosexuality (1)
Infections (17) · Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (10) · Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (8) · Female Urogenital Diseases (5) · Male Urogenital Diseases (5) · Postoperative Complications (5) · Urologic Diseases (5) · Wound Infection (5) · Bacterial Infections and Mycoses (3) · Pregnancy Complications (3) · Genital Diseases (2) · Neoplasms (2) · Obstetric Labor Complications (2)
Amoxicillin (6) · Antibiotic Prophylaxis (6) · Cefazolin (6) · Trimethoprim, Sulfamethoxazole Drug Combination (3) · Vancomycin (3) · Amdinocillin Pivoxil (2) · Amoxicillin-Potassium Clavulanate Combination (2) · Anti-Bacterial Agents (2) · Cefuroxime (2) · Ciprofloxacin (2) · Linezolid (2) · Nitrofurantoin (2) · Trimethoprim (2) · Ampicillin (1) · Blood Specimen Collection (1)
Central Hospital, Nancy, France (3) · Hamilton Health Sciences Corporation (2) · University Hospital, Strasbourg, France (2) · Acibadem Maslak Hospital (1) · Agnaldo Rocha de Souza Junior (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Atlantic Health System (1) · Barretos Cancer Hospital (1) · Brigham and Women's Hospital (1) · Centre Hospitalier de Saint-Denis (1) · Copenhagen University Hospital, Rigshospitalet (1) · Duke University (1) · Fabiola Soares Moreira Campos (1) · Federal University of Mato Grosso (1)
France (10) · United States (8) · Brazil (5) · Italy (3) · Denmark (2) · Netherlands (2) · United Kingdom (2) · Canada (1) · Colombia (1) · Czechia (1) · India (1) · Indonesia (1) · Israel (1) · Pakistan (1) · Slovakia (1)
Ahmad Zia Ud Din (1) · Alessandra C Leite, MsC (1) · Alexandra Bicki, MD (1) · Andrea SS Carbone, MsC (1) · Andrew Kirby (1) · Carlo Pietrasanta, MD,PhD (1) · Carolyn Botros, DO (1) · Cassia B Reis, PhD (1) · Daniele Porru, MD (1) · Dominik Mertz, MD, MSc (1) · Dr. Viniyendra Pamecha (1)
PMID 23325435, PMID 30558680, PMID 32698642, PMID 34632426, PMID 35075765, PMID 38494157, PMID 39836173, PMID 39880423, PMID 40722189, PMID 42238679